dbPTM

DAS2_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DAS2_YEAST
UniProt AC	Q12084
Protein Name	Putative uridine kinase DAS2
Gene Name	DAS2
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	232
Subcellular Localization	Cytoplasm . Nucleus .
Protein Description	Putative uridine kinase identified in a screen for mutants with increased levels of rDNA transcription..
Protein Sequence	MDRKAVEEKRIVISIGGGHATGVGAIALDLQNTFKSLYNSINIRVINLDNMIEGNIKSYNNNDYDFDNILNLVYEKHAVTSQNDMIQHDYEDPIDLIIVCGCYALYDKRINEISQLKVFLDSDADKRLISLIKKKNVGSNEQLAQLITEYMDHLRPEMQQYIEPTRTFADLIIPSTNENLGRAVLVDGIVKAIEDTKSQIEGNNTNNKIRPRLWDFEAETMDLEKDRYYDLS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
114	Phosphorylation	DKRINEISQLKVFLD HHHHHHHHCCEEECC	24.23	19795423
197	Ubiquitination	VKAIEDTKSQIEGNN HHHHHHHHHHHCCCC	53.32	23749301
232	Phosphorylation	KDRYYDLS------- CCCCCCCC-------	34.97	21440633

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DAS2_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DAS2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DAS2_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DAS2_YEAST	DAS2	physical	11283351
URK1_YEAST	URK1	physical	11283351
RPAB1_YEAST	RPB5	genetic	27708008
MED6_YEAST	MED6	genetic	27708008
HPC2_YEAST	HPC2	genetic	27708008
BUD2_YEAST	BUD2	genetic	27708008
CDC24_YEAST	CDC24	genetic	27708008
RSP5_YEAST	RSP5	genetic	27708008
CDC4_YEAST	CDC4	genetic	27708008
PRS8_YEAST	RPT6	genetic	27708008
CDC20_YEAST	CDC20	genetic	27708008
SWC4_YEAST	SWC4	genetic	27708008
SDO1_YEAST	SDO1	genetic	27708008
RU1C_YEAST	YHC1	genetic	27708008
HAS1_YEAST	HAS1	genetic	27708008
DYR_YEAST	DFR1	genetic	27708008
BUR1_YEAST	SGV1	genetic	27708008
YAJ9_YEAST	YAR029W	genetic	27708008
AVT5_YEAST	AVT5	genetic	27708008
SWC5_YEAST	SWC5	genetic	27708008
RMD9L_YEAST	YBR238C	genetic	27708008
STE50_YEAST	STE50	genetic	27708008
ATG22_YEAST	ATG22	genetic	27708008
MEI4_YEAST	MEI4	genetic	27708008
VFA1_YEAST	VFA1	genetic	27708008
GUP1_YEAST	GUP1	genetic	27708008
MRM2_YEAST	MRM2	genetic	27708008
ATG1_YEAST	ATG1	genetic	27708008
SAY1_YEAST	SAY1	genetic	27708008
BNA3_YEAST	BNA3	genetic	27708008
REE1_YEAST	REE1	genetic	27708008
URA8_YEAST	URA8	genetic	27708008
ILM1_YEAST	ILM1	genetic	27708008
RS27A_YEAST	RPS27A	genetic	27708008
PXA2_YEAST	PXA2	genetic	27708008
SAC1_YEAST	SAC1	genetic	27708008
ARP6_YEAST	ARP6	genetic	27708008
IDHC_YEAST	IDP2	genetic	27708008
RL37A_YEAST	RPL37A	genetic	27708008
REH1_YEAST	REH1	genetic	27708008
JLP2_YEAST	JLP2	genetic	27708008
PET8_YEAST	PET8	genetic	27708008
CTU2_YEAST	NCS2	genetic	27708008
NM111_YEAST	NMA111	genetic	27708008
AHC1_YEAST	AHC1	genetic	27708008
RL21B_YEAST	RPL21B	genetic	27708008
NIP80_YEAST	NIP100	genetic	27708008
AP1G1_YEAST	APL4	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DAS2_YEAST

Related Literatures of Post-Translational Modification