IDHC_YEAST - dbPTM
IDHC_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID IDHC_YEAST
UniProt AC P41939
Protein Name Isocitrate dehydrogenase [NADP] cytoplasmic
Gene Name IDP2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 412
Subcellular Localization Cytoplasm.
Protein Description May function in the production of NADPH for fatty acid and sterol synthesis..
Protein Sequence MTKIKVANPIVEMDGDEQTRIIWHLIRDKLVLPYLDVDLKYYDLSVEYRDQTNDQVTVDSATATLKYGVAVKCATITPDEARVEEFHLKKMWKSPNGTIRNILGGTVFREPIIIPRIPRLVPQWEKPIIIGRHAFGDQYKATDVIVPEEGELRLVYKSKSGTHDVDLKVFDYPEHGGVAMMMYNTTDSIEGFAKASFELAIERKLPLYSTTKNTILKKYDGKFKDVFEAMYARSYKEKFESLGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVESDIVAQGFGSLGLMTSVLITPDGKTFESEAAHGTVTRHFRQHQQGKETSTNSIASIFAWTRGIIQRGKLDNTPDVVKFGQILESATVNTVQEDGIMTKDLALILGKSERSAYVTTEEFIDAVESRLKKEFEAAAL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
41PhosphorylationYLDVDLKYYDLSVEY
EECCEEEEEEEEEEE		14.9827214570
45PhosphorylationDLKYYDLSVEYRDQT
EEEEEEEEEEEECCC		15.2527214570
48PhosphorylationYYDLSVEYRDQTNDQ
EEEEEEEEECCCCCE		19.8227214570
77PhosphorylationAVKCATITPDEARVE
EEEEEEECCCHHHHH		21.9727214570
93AcetylationFHLKKMWKSPNGTIR
HHHHHHCCCCCCCCC		53.1625381059
126UbiquitinationRLVPQWEKPIIIGRH
CCCCCCCCCEEEEEC		38.2624961812
126AcetylationRLVPQWEKPIIIGRH
CCCCCCCCCEEEEEC		38.2625381059
162PhosphorylationVYKSKSGTHDVDLKV
EEECCCCCCEEEEEE		23.2229734811
260AcetylationDMVAQMLKSKGGYII
HHHHHHHHHCCCEEE		44.7924489116
354UbiquitinationDNTPDVVKFGQILES
CCCCCCCHHHHHHHH		43.5619722269
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of IDHC_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of IDHC_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of IDHC_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
IDHH_YEASTIDP3genetic
16941010
IDH1_YEASTIDH1genetic
21623372
CBS_YEASTCYS4genetic
21623372
IDH2_YEASTIDH2genetic
21623372
SYSM_YEASTDIA4genetic
21623372
RM01_YEASTMRPL1genetic
27708008
INO4_YEASTINO4genetic
27708008
SHE1_YEASTSHE1genetic
27708008
CSG2_YEASTCSG2genetic
27708008
ECM8_YEASTECM8genetic
27708008
SIF2_YEASTSIF2genetic
27708008
SEC66_YEASTSEC66genetic
27708008
SWC5_YEASTSWC5genetic
27708008
RV161_YEASTRVS161genetic
27708008
RIM1_YEASTRIM1genetic
27708008
TPS2_YEASTTPS2genetic
27708008
RPA14_YEASTRPA14genetic
27708008
GNTK_YEASTYDR248Cgenetic
27708008
YPS7_YEASTYPS7genetic
27708008
RLA4_YEASTRPP2Bgenetic
27708008
SHE9_YEASTSHE9genetic
27708008
AIM11_YEASTAIM11genetic
27708008
PDR1_YEASTPDR1genetic
27708008
AAKG_YEASTSNF4genetic
27708008
XRN1_YEASTXRN1genetic
27708008
VAM7_YEASTVAM7genetic
27708008
GTR2_YEASTGTR2genetic
27708008
GLPK_YEASTGUT1genetic
27708008
MED20_YEASTSRB2genetic
27708008
SDHX_YEASTYJL045Wgenetic
27708008
MOG1_YEASTMOG1genetic
27708008
MDM35_YEASTMDM35genetic
27708008
CBT1_YEASTCBT1genetic
27708008
COX12_YEASTCOX12genetic
27708008
ATP18_YEASTATP18genetic
27708008
RCO1_YEASTRCO1genetic
27708008
OCA2_YEASTOCA2genetic
27708008
SWS2_YEASTSWS2genetic
27708008
MKT1_YEASTMKT1genetic
27708008
RRP6_YEASTRRP6genetic
27708008
YO08A_YEASTYOR008C-Agenetic
27708008
VPS21_YEASTVPS21genetic
27708008
IDH2_YEASTIDH2genetic
27708008
LGE1_YEASTLGE1genetic
27708008
RL21B_YEASTRPL21Bgenetic
27708008
TGS1_YEASTTGS1genetic
27708008
AIM44_YEASTAIM44genetic
27708008
NCBP2_YEASTCBC2genetic
27708008
MED1_YEASTMED1genetic
27708008
YP089_YEASTYPR089Wgenetic
27708008
MSS18_YEASTMSS18genetic
27708008
URN1_YEASTURN1genetic
27708008
CTK3_YEASTCTK3genetic
27453043
RTG1_YEASTRTG1genetic
27453043
SWI4_YEASTSWI4genetic
27453043
GCR2_YEASTGCR2genetic
27453043
DCAM_YEASTSPE2genetic
27453043
DCOR_YEASTSPE1genetic
27453043
SNF2_YEASTSNF2genetic
27453043
ERG26_YEASTERG26genetic
27453043
VPS53_YEASTVPS53genetic
27453043
CTK2_YEASTCTK2genetic
27453043
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of IDHC_YEAST

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Related Literatures of Post-Translational Modification

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