DCAM_YEAST - dbPTM
DCAM_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID DCAM_YEAST
UniProt AC P21182
Protein Name S-adenosylmethionine decarboxylase proenzyme
Gene Name SPE2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 396
Subcellular Localization
Protein Description S-adenosylmethionine decarboxylase is essential for normal growth, sporulation, maintenance of ds-RNA virus, biosynthesis of spermine and spermidine..
Protein Sequence MTVTIKELTNHNYIDHELSATLDSTDAFEGPEKLLEIWFFPHKKSITTEKTLRNIGMDRWIEILKLVKCEVLSMKKTKELDAFLLSESSLFVFDHKLTMKTCGTTTTLFCLEKLFQIVEQELSWAFRTTQGGKYKPFKVFYSRRCFLFPCKQAAIHQNWADEVDYLNKFFDNGKSYSVGRNDKSNHWNLYVTETDRSTPKGKEYIEDDDETFEVLMTELDPECASKFVCGPEASTTALVEPNEDKGHNLGYQMTKNTRLDEIYVNSAQDSDLSFHHDAFAFTPCGYSSNMILAEKYYYTLHVTPEKGWSYASFESNIPVFDISQGKQDNLDVLLHILNVFQPREFSMTFFTKNYQNQSFQKLLSINESLPDYIKLDKIVYDLDDYHLFYMKLQKKI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
88Pyruvic acid (Ser)DAFLLSESSLFVFDH
CEEEECCCCEEEECC		29.03-
88PyruvateDAFLLSESSLFVFDH
CEEEECCCCEEEECC		29.032266128
298PhosphorylationILAEKYYYTLHVTPE
EEEEEEEEEEEECCC		10.3525371407
374AcetylationESLPDYIKLDKIVYD
CCCCCCEEEHHEEEE		44.3924489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of DCAM_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of DCAM_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of DCAM_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PCP1_YEASTPCP1genetic
9442051
SODC_YEASTSOD1genetic
8506320
DCOR_YEASTSPE1genetic
7961484
MRS1_YEASTMRS1physical
16554755
AHA1_YEASTAHA1physical
11283351
FEN2_YEASTFEN2genetic
17284612
RPE_YEASTRPE1genetic
21623372
GGPPS_YEASTBTS1genetic
21623372
DCOR_YEASTSPE1genetic
21623372
THRC_YEASTTHR4genetic
21623372
URA8_YEASTURA8genetic
21623372
MCM1_YEASTMCM1genetic
27708008
CDC37_YEASTCDC37genetic
27708008
CDC1_YEASTCDC1genetic
27708008
SNU56_YEASTSNU56genetic
27708008
MOB2_YEASTMOB2genetic
27708008
SAD1_YEASTSAD1genetic
27708008
CDC12_YEASTCDC12genetic
27708008
NOP56_YEASTNOP56genetic
27708008
AFG2_YEASTAFG2genetic
27708008
TAF11_YEASTTAF11genetic
27708008
SEC12_YEASTSEC12genetic
27708008
PRP4_YEASTPRP4genetic
27708008
CHK1_YEASTCHK1genetic
27708008
TMA64_YEASTTMA64genetic
27708008
LIC4_YEASTATC1genetic
27708008
RL29_YEASTRPL29genetic
27708008
AP3B_YEASTAPL6genetic
27708008
YJH0_YEASTYJL070Cgenetic
27708008
PIR5_YEASTYJL160Cgenetic
27708008
EOS1_YEASTEOS1genetic
27708008
HOL1_YEASTHOL1genetic
27708008
YPK9_YEASTYPK9genetic
27708008
GGPPS_YEASTBTS1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of DCAM_YEAST

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Related Literatures of Post-Translational Modification

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