ERG26_YEAST - dbPTM
ERG26_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ERG26_YEAST
UniProt AC P53199
Protein Name Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating
Gene Name ERG26
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 349
Subcellular Localization Endoplasmic reticulum membrane
Peripheral membrane protein .
Protein Description
Protein Sequence MSKIDSVLIIGGSGFLGLHLIQQFFDINPKPDIHIFDVRDLPEKLSKQFTFNVDDIKFHKGDLTSPDDMENAINESKANVVVHCASPMHGQNPDIYDIVNVKGTRNVIDMCKKCGVNILVYTSSAGVIFNGQDVHNADETWPIPEVPMDAYNETKAIAEDMVLKANDPSSDFYTVALRPAGIFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQKLLDPKTRTAVSGETFFITNDTPTYFWALARTVWKADGHIDKHVIVLKRPVAICAGYLSEWVSKMLGKEPGLTPFRVKIVCAYRYHNIAKAKKLLGYTPRVGIEEGINKTLAWMDEGL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
44UbiquitinationDVRDLPEKLSKQFTF
EHHHCCHHHHHCEEE		57.0023749301
47UbiquitinationDLPEKLSKQFTFNVD
HCCHHHHHCEEEEHH		60.9217644757
57UbiquitinationTFNVDDIKFHKGDLT
EEEHHHEEEECCCCC		48.7017644757
77UbiquitinationENAINESKANVVVHC
HHHHHHHHCCEEEEC		37.4917644757
102UbiquitinationIYDIVNVKGTRNVID
CHHEECCCCCHHHHH		49.7317644757
273AcetylationKADGHIDKHVIVLKR
CCCCCCCCEEEEECC		38.8922865919
279UbiquitinationDKHVIVLKRPVAICA
CCEEEEECCCHHHHH		43.7017644757
295UbiquitinationYLSEWVSKMLGKEPG
HHHHHHHHHHCCCCC		28.6417644757
323UbiquitinationYHNIAKAKKLLGYTP
CCHHHHHHHHHCCCC		43.1617644757
324UbiquitinationHNIAKAKKLLGYTPR
CHHHHHHHHHCCCCC		54.5317644757
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ERG26_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ERG26_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ERG26_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SUR2_YEASTSUR2genetic
12006573
ATU2_YEASTCCC2genetic
12006573
MDN1_YEASTMDN1physical
16429126
TBB_YEASTTUB2physical
16429126
TMEDA_YEASTERV25physical
18467557
ORM2_YEASTORM2physical
18467557
DEP1_YEASTDEP1genetic
20093466
YBF9_YEASTYBL059Wgenetic
20093466
RXT2_YEASTRXT2genetic
20093466
MTC3_YEASTMTC3genetic
20093466
TNA1_YEASTTNA1genetic
20093466
SDS3_YEASTSDS3genetic
20093466
YKC3_YEASTYKL023Wgenetic
20093466
IZH3_YEASTIZH3genetic
20093466
YL040_YEASTAFB1genetic
20093466
UPS1_YEASTUPS1genetic
20093466
ENT2_YEASTENT2genetic
20093466
ECM22_YEASTECM22genetic
20093466
CCW14_YEASTCCW14genetic
20093466
RL6B_YEASTRPL6Bgenetic
20093466
PLB2_YEASTPLB2genetic
20093466
PKR1_YEASTPKR1genetic
20093466
SAP30_YEASTSAP30genetic
20093466
APP1_YEASTAPP1genetic
20093466
SIN3_YEASTSIN3genetic
20093466
PHO80_YEASTPHO80genetic
20093466
DIA2_YEASTDIA2genetic
20093466
NPT1_YEASTNPT1genetic
20093466
YP089_YEASTYPR089Wgenetic
20093466
ERG4_YEASTERG4physical
16300994
ERG3_YEASTERG3physical
16300994
ERG6_YEASTERG6physical
16300994
ERG28_YEASTERG28physical
16300994
ERG27_YEASTERG27physical
16300994
MSMO_YEASTERG25physical
16300994
ERG24_YEASTERG24physical
16300994
CP51_YEASTERG11physical
16300994
ERG7_YEASTERG7physical
16300994
ERG1_YEASTERG1physical
16300994
FDFT_YEASTERG9physical
16300994
PHO86_YEASTPHO86genetic
23891562
YPT31_YEASTYPT31genetic
23891562
AP1B1_YEASTAPL2genetic
23891562
PACC_YEASTRIM101genetic
23891562
AYR1_YEASTAYR1genetic
23891562
FEN1_YEASTRAD27genetic
23891562
HMCS_YEASTERG13genetic
23891562
ELO3_YEASTELO3genetic
23891562
CSG2_YEASTCSG2genetic
23891562
THIL_YEASTERG10genetic
23891562
EMC1_YEASTEMC1genetic
23891562
KIME_YEASTERG12genetic
23891562
RAD51_YEASTRAD51genetic
23891562
PSA3_YEASTPRE9genetic
23891562
PRS6B_YEASTRPT3genetic
23891562
PSB5_YEASTPRE2genetic
23891562
PSA4_YEASTPRE6genetic
23891562
HMDH1_YEASTHMG1genetic
23891562
ERG7_YEASTERG7genetic
23891562
BOS1_YEASTBOS1genetic
27708008
NAB3_YEASTNAB3genetic
27708008
TIM22_YEASTTIM22genetic
27708008
RMRP_YEASTSNM1genetic
27708008
FDFT_YEASTERG9genetic
27708008
ESS1_YEASTESS1genetic
27708008
RSC4_YEASTRSC4genetic
27708008
TAD3_YEASTTAD3genetic
27708008
GPI12_YEASTGPI12genetic
27708008
SEC63_YEASTSEC63genetic
27708008
RXT2_YEASTRXT2genetic
27708008
SDS3_YEASTSDS3genetic
27708008
MGA2_YEASTMGA2genetic
27708008
CTK1_YEASTCTK1genetic
27708008
PKR1_YEASTPKR1genetic
27708008
SAP30_YEASTSAP30genetic
27708008
PHO23_YEASTPHO23genetic
27708008
SIN3_YEASTSIN3genetic
27708008
NPT1_YEASTNPT1genetic
27708008
MNE1_YEASTMNE1genetic
27708008
RXT2_YEASTRXT2genetic
29674565
CDC23_YEASTCDC23genetic
29674565
BRE1_YEASTBRE1genetic
29674565
CDC1_YEASTCDC1genetic
29674565
COG3_YEASTCOG3genetic
29674565
SEC4_YEASTSEC4genetic
29674565
ATC7_YEASTNEO1genetic
29674565
SDS3_YEASTSDS3genetic
29674565
PRS7_YEASTRPT1genetic
29674565
PML39_YEASTPML39genetic
29674565
PKR1_YEASTPKR1genetic
29674565
SAP30_YEASTSAP30genetic
29674565
SCS7_YEASTSCS7genetic
29674565
SIN3_YEASTSIN3genetic
29674565
VTS1_YEASTVTS1genetic
29674565
HSP7F_YEASTSSE1genetic
29674565
NAB3_YEASTNAB3genetic
29674565
RPN7_YEASTRPN7genetic
29674565
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ERG26_YEAST

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Related Literatures of Post-Translational Modification

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