ERG28_YEAST - dbPTM
ERG28_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ERG28_YEAST
UniProt AC P40030
Protein Name Ergosterol biosynthetic protein 28
Gene Name ERG28
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 148
Subcellular Localization Endoplasmic reticulum membrane
Multi-pass membrane protein .
Protein Description Has a role as a scaffold to help anchor ERG25, ERG26 and ERG27 to the endoplasmic reticulum. May also be responsible for facilitating their interaction..
Protein Sequence MFSLQDVITTTKTTLAAMPKGYLPKWLLFISIVSVFNSIQTYVSGLELTRKVYERKPTETTHLSARTFGTWTFISCVIRFYGAMYLNEPHIFELVFMSYMVALFHFGSELLIFRTCKLGKGFMGPLVVSTTSLVWMYKQREYYTGVAW
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of ERG28_YEAST !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ERG28_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ERG28_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ERG28_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ERG6_YEASTERG6physical
15522820
ERG6_YEASTERG6physical
15995173
ERG1_YEASTERG1physical
15995173
CP51_YEASTERG11physical
15995173
MSMO_YEASTERG25physical
15995173
ERG26_YEASTERG26physical
15995173
ERG27_YEASTERG27physical
15995173
ERG28_YEASTERG28physical
15995173
UPC2_YEASTUPC2genetic
16702413
ECM22_YEASTECM22genetic
16702413
YND1_YEASTYND1genetic
16702413
GDA1_YEASTGDA1genetic
16702413
ERG6_YEASTERG6physical
16300994
ERG28_YEASTERG28physical
16300994
ERG27_YEASTERG27physical
16300994
MSMO_YEASTERG25physical
16300994
CP51_YEASTERG11physical
16300994
TAR1_YEASTTAR1genetic
16702413
PDR10_YEASTPDR10physical
23831759

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ERG28_YEAST

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Related Literatures of Post-Translational Modification

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