| UniProt ID | GDA1_YEAST | |
|---|---|---|
| UniProt AC | P32621 | |
| Protein Name | Guanosine-diphosphatase | |
| Gene Name | GDA1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 518 | |
| Subcellular Localization |
Golgi apparatus membrane Single-pass type II membrane protein . |
|
| Protein Description | After transfer of sugars to endogenous macromolecular acceptors, the enzyme converts nucleoside diphosphates to nucleoside monophosphates which in turn exit the Golgi lumen in a coupled antiporter reaction, allowing entry of additional nucleotide sugar from the cytosol.. | |
| Protein Sequence | MAPIFRNYRFAIGAFAVIMLILLIKTSSIGPPSIARTVTPNASIPKTPEDISILPVNDEPGYLQDSKTEQNYPELADAVKSQTSQTCSEEHKYVIMIDAGSTGSRVHIYKFDVCTSPPTLLDEKFDMLEPGLSSFDTDSVGAANSLDPLLKVAMNYVPIKARSCTPVAVKATAGLRLLGDAKSSKILSAVRDHLEKDYPFPVVEGDGVSIMGGDEEGVFAWITTNYLLGNIGANGPKLPTAAVFDLGGGSTQIVFEPTFPINEKMVDGEHKFDLKFGDENYTLYQFSHLGYGLKEGRNKVNSVLVENALKDGKILKGDNTKTHQLSSPCLPPKVNATNEKVTLESKETYTIDFIGPDEPSGAQCRFLTDEILNKDAQCQSPPCSFNGVHQPSLVRTFKESNDIYIFSYFYDRTRPLGMPLSFTLNELNDLARIVCKGEETWNSVFSGIAGSLDELESDSHFCLDLSFQVSLLHTGYDIPLQRELRTGKKIANKEIGWCLGASLPLLKADNWKCKIQSA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 37 | Phosphorylation | GPPSIARTVTPNASI CCCCCCCCCCCCCCC | 21.51 | 21126336 | |
| 41 | N-linked_Glycosylation | IARTVTPNASIPKTP CCCCCCCCCCCCCCC | 36.63 | - | |
| 81 | Phosphorylation | ELADAVKSQTSQTCS HHHHHHHHHCCCCCC | 31.90 | 28889911 | |
| 110 | Acetylation | GSRVHIYKFDVCTSP CCEEEEEEEEECCCC | 34.19 | 24489116 | |
| 271 | Acetylation | KMVDGEHKFDLKFGD EECCCCEEEEEEECC | 35.95 | 24489116 | |
| 280 | N-linked_Glycosylation | DLKFGDENYTLYQFS EEEECCCCEEEEEEH | 39.57 | - | |
| 310 | Acetylation | VLVENALKDGKILKG HHHHHHHHCCCCCCC | 63.12 | 24489116 | |
| 313 | Acetylation | ENALKDGKILKGDNT HHHHHCCCCCCCCCC | 55.81 | 24489116 | |
| 335 | N-linked_Glycosylation | PCLPPKVNATNEKVT CCCCCCCCCCCCEEE | 47.36 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GDA1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GDA1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GDA1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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