ALG10_YEAST - dbPTM
ALG10_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ALG10_YEAST
UniProt AC P50076
Protein Name Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase
Gene Name DIE2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 525
Subcellular Localization Endoplasmic reticulum membrane
Multi-pass membrane protein .
Protein Description Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol..
Protein Sequence MDAKKNTGEANNDVLEEEAAIQLIAPGIARNLTQEVITGIFCNVVIYPLLLIYFVLTFRYMTTNIVPYEFIDEKFHVGQTLTYLKGKWTQWDPKITTPPGIYILGLINYYCIKPIFKSWSTLTILRLVNLLGGIIVFPILVLRPIFLFNALGFWPVSLMSFPLMTTYYYLFYTDVWSTILILQSLSCVLTLPFGPVKSIWLSAFFAGVSCLFRQTNIIWTGFIMILAVERPAILQKQFNTHTFNNYLKLFIHAIDDFSNLVLPYMINFVLFFIYLIWNRSITLGDKSSHSAGLHIVQIFYCFTFITVFSLPIWISRNFMKLYKLRIKRKPVQTFFEFIGIMLIIRYFTKVHPFLLADNRHYTFYLFRRLIGNKSRLIKYFFMTPIYHFSTFAYLEVMRPNQLTFHPITPLPIKEPVHLPIQLTHVSWTALITCTMVTIVPSPLFEPRYYILPYFFWRIFITCSCEPLIKDLKPAKEGENPITISSTKRLFMEFLWFMLFNVVTLVIFSKVSFPWTTEPYLQRIIW
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
31N-linked_GlycosylationIAPGIARNLTQEVIT
HCHHHHHHCCHHHHH
38.12-
278N-linked_GlycosylationFFIYLIWNRSITLGD
HHHHHHHHCCCCCCC
22.34-
372N-linked_GlycosylationLFRRLIGNKSRLIKY
HHHHHHCCHHHHHHH
31.94-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ALG10_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ALG10_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ALG10_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RPOM_YEASTRPO41genetic
14764870
OST5_YEASTOST5genetic
14764870
OST3_YEASTOST3genetic
14764870
OST5_YEASTOST5genetic
16269340
OST3_YEASTOST3genetic
16269340
HAC1_YEASTHAC1genetic
16269340
OSTB_YEASTWBP1genetic
16269340
IRE1_YEASTIRE1genetic
16269340
OST1_YEASTOST1genetic
16269340
GAS1_YEASTGAS1genetic
16269340
GUP1_YEASTGUP1genetic
16269340
ATC1_YEASTPMR1genetic
16269340
KEI1_YEASTKEI1genetic
16269340
AP3B_YEASTAPL6genetic
16269340
GPI8_YEASTGPI8genetic
16269340
PLMT_YEASTOPI3genetic
16269340
COPE_YEASTSEC28genetic
16269340
ICE2_YEASTICE2genetic
16269340
ILM1_YEASTILM1genetic
16269340
RIC1_YEASTRIC1genetic
16269340
GET1_YEASTGET1genetic
16269340
SCS7_YEASTSCS7genetic
16269340
MDM12_YEASTMDM12genetic
14764870
ALG12_YEASTALG12genetic
19325107
ALG3_YEASTALG3genetic
19325107
ALG5_YEASTALG5genetic
19325107
ALG6_YEASTALG6genetic
19325107
ALG8_YEASTALG8genetic
19325107
ALG9_YEASTALG9genetic
19325107
PLMT_YEASTOPI3genetic
19325107
OST5_YEASTOST5genetic
19325107
SPT4_YEASTSPT4genetic
19325107
VPS1_YEASTVPS1genetic
19325107
CWH43_YEASTCWH43genetic
19325107
ERP1_YEASTERP1genetic
19325107
GDA1_YEASTGDA1genetic
19325107
ITR1_YEASTITR1genetic
19325107
GLU2A_YEASTROT2genetic
19325107
SUM1_YEASTSUM1genetic
19325107
VPS27_YEASTVPS27genetic
19325107
SLP1_YEASTSLP1genetic
19325107
SSH1_YEASTSSH1genetic
19325107
HSP71_YEASTSSA1physical
22940862
HAC1_YEASTHAC1genetic
23891562
IRE1_YEASTIRE1genetic
23891562
STT3_YEASTSTT3genetic
23891562
OST5_YEASTOST5genetic
23891562
OSTB_YEASTWBP1genetic
23891562
OSTD_YEASTSWP1genetic
23891562
OST1_YEASTOST1genetic
23891562
OST3_YEASTOST3genetic
23891562
STE24_YEASTSTE24genetic
23891562
PSD1_YEASTPSD1genetic
23891562
GET2_YEASTGET2genetic
23891562
RIC1_YEASTRIC1genetic
23891562
VPS1_YEASTVPS1genetic
23891562
SRO7_YEASTSRO7genetic
23891562
CSG2_YEASTCSG2genetic
23891562
ICE2_YEASTICE2genetic
23891562
TPS2_YEASTTPS2genetic
27708008
FKS1_YEASTFKS1genetic
27708008
GPI17_YEASTGPI17genetic
27708008
GPI19_YEASTGPI19genetic
27708008
ACT_YEASTACT1genetic
27708008
STT3_YEASTSTT3genetic
27708008
ATC7_YEASTNEO1genetic
27708008
OST1_YEASTOST1genetic
27708008
GRP78_YEASTKAR2genetic
27708008
TAD3_YEASTTAD3genetic
27708008
CDC91_YEASTGAB1genetic
27708008
TAF11_YEASTTAF11genetic
27708008
GPI12_YEASTGPI12genetic
27708008
OST2_YEASTOST2genetic
27708008
SEC63_YEASTSEC63genetic
27708008
MDM10_YEASTMDM10genetic
27708008
HEK2_YEASTHEK2genetic
27708008
PTH2_YEASTPTH2genetic
27708008
GPR1_YEASTGPR1genetic
27708008
OST4_YEASTOST4genetic
27708008
SNF11_YEASTSNF11genetic
27708008
MNN10_YEASTMNN10genetic
27708008
HAC1_YEASTHAC1genetic
27708008
YFK5_YEASTYFR035Cgenetic
27708008
OST5_YEASTOST5genetic
27708008
YGY5_YEASTYGL235Wgenetic
27708008
IRE1_YEASTIRE1genetic
27708008
YJ24_YEASTKCH1genetic
27708008
STE24_YEASTSTE24genetic
27708008
MDM35_YEASTMDM35genetic
27708008
CWP2_YEASTCWP2genetic
27708008
ERG3_YEASTERG3genetic
27708008
CSF1_YEASTCSF1genetic
27708008
ICT1_YEASTICT1genetic
27708008
ARV1_YEASTARV1genetic
27708008
ATP10_YEASTATP10genetic
27708008
UBX2_YEASTUBX2genetic
27708008
OST6_YEASTOST6genetic
27708008
VPS9_YEASTVPS9genetic
27708008
CTK3_YEASTCTK3genetic
27708008
OSW5_YEASTOSW5genetic
27708008
MTQ1_YEASTMTQ1genetic
27708008
TOM70_YEASTTOM70genetic
27708008
OST3_YEASTOST3genetic
27708008
COQ7_YEASTCAT5genetic
27708008
MSC6_YEASTMSC6genetic
27708008
SUR1_YEASTSUR1genetic
27708008
CR3L1_HUMANCREB3L1physical
27107014

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ALG10_YEAST

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Related Literatures of Post-Translational Modification

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