OSW5_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: OSW5_YEAST
• UniProt AC: P40219
• Protein Name: Outer spore wall protein 5
• Gene Name: OSW5
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 148
• Subcellular Localization: Membrane; Multi-pass membrane protein.
• Protein Description: Involved in spore wall assembly..
• Protein Sequence: MVSTATFFFFVYLTLFVVIGFFSSLFIIPLLGISFVFAIGVVSFGFCSNMSFKMAQLIYVRADAFLKKVLDKMALQTQPAQLQEPQEPLSTLRPVSNPTIPSPLRQTARPSKFVTEEDVIFEPVSAQSAIARSLETTANKAGNKFQLS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
90	Phosphorylation	QEPQEPLSTLRPVSN CCCCCCHHHCCCCCC	35.79	21440633
91	Phosphorylation	EPQEPLSTLRPVSNP CCCCCHHHCCCCCCC	34.17	23607784
96	Phosphorylation	LSTLRPVSNPTIPSP HHHCCCCCCCCCCCC	39.51	25521595
99	Phosphorylation	LRPVSNPTIPSPLRQ CCCCCCCCCCCCCCC	50.17	21440633
102	Phosphorylation	VSNPTIPSPLRQTAR CCCCCCCCCCCCCCC	32.49	25521595

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of OSW5_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of OSW5_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of OSW5_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SEC66_YEAST	SEC66	genetic	19325107
HOP2_YEAST	HOP2	genetic	19325107
PRPD_YEAST	PDH1	physical	21748599
OM14_YEAST	OM14	physical	21748599
ATPG_YEAST	ATP3	physical	21748599
PEX8_YEAST	PEX8	physical	21748599
TOM22_YEAST	TOM22	physical	21748599
IML2_YEAST	IML2	physical	21748599
HFD1_YEAST	HFD1	physical	21748599
AYR1_YEAST	AYR1	physical	21748599
FMP52_YEAST	FMP52	physical	21748599
GSF2_YEAST	GSF2	physical	21748599
DPM1_YEAST	DPM1	physical	21748599
DIC1_YEAST	DIC1	physical	21748599
DAP1_YEAST	DAP1	physical	21748599
YTP1_YEAST	YTP1	physical	21748599
PEX19_YEAST	PEX19	physical	21748599
DSL1_YEAST	DSL1	physical	21748599
HAC1_YEAST	HAC1	genetic	23891562
OST5_YEAST	OST5	genetic	23891562
MCES_YEAST	ABD1	genetic	27708008
FAD1_YEAST	FAD1	genetic	27708008
SEC7_YEAST	SEC7	genetic	27708008
NUP57_YEAST	NUP57	genetic	27708008
COAD_YEAST	CAB4	genetic	27708008
CWC16_YEAST	YJU2	genetic	27708008
TF2B_YEAST	SUA7	genetic	27708008
HAP5_YEAST	HAP5	genetic	27708008
PSB6_YEAST	PRE7	genetic	27708008
SC61G_YEAST	SSS1	genetic	27708008
PGTB1_YEAST	CDC43	genetic	27708008
CDC3_YEAST	CDC3	genetic	27708008
YCQ6_YEAST	YCR016W	genetic	27708008
RL8A_YEAST	RPL8A	genetic	27708008
BFA1_YEAST	BFA1	genetic	27708008
CTK1_YEAST	CTK1	genetic	27708008
ELO3_YEAST	ELO3	genetic	27708008
SEI1_YEAST	FLD1	genetic	27708008
TDA5_YEAST	TDA5	genetic	27708008
RCF2_YEAST	RCF2	genetic	27708008
SRO7_YEAST	SRO7	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-102, AND MASSSPECTROMETRY.
PubMed: 18407956

"Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases.";
Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.;
Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-102, AND MASSSPECTROMETRY.
PubMed: 17563356