ATPG_YEAST - dbPTM
ATPG_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ATPG_YEAST
UniProt AC P38077
Protein Name ATP synthase subunit gamma, mitochondrial
Gene Name ATP3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 311
Subcellular Localization Mitochondrion. Mitochondrion inner membrane
Peripheral membrane protein.
Protein Description Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits..
Protein Sequence MLSRIVSNNATRSVMCHQAQVGILYKTNPVRTYATLKEVEMRLKSIKNIEKITKTMKIVASTRLSKAEKAKISAKKMDEAEQLFYKNAETKNLDVEATETGAPKELIVAITSDKGLCGSIHSQLAKAVRRHLNDQPNADIVTIGDKIKMQLLRTHPNNIKLSINGIGKDAPTFQESALIADKLLSVMKAGTYPKISIFYNDPVSSLSFEPSEKPIFNAKTIEQSPSFGKFEIDTDANVPRDLFEYTLANQMLTAMAQGYAAEISARRNAMDNASKNAGDMINRYSILYNRTRQAVITNELVDIITGASSLG
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
85PhosphorylationDEAEQLFYKNAETKN
HHHHHHHHHCCCCCC		16.3625882841
86AcetylationEAEQLFYKNAETKNL
HHHHHHHHCCCCCCC		42.2024489116
90PhosphorylationLFYKNAETKNLDVEA
HHHHCCCCCCCCEEE		23.8727017623
91AcetylationFYKNAETKNLDVEAT
HHHCCCCCCCCEEEC		47.2024489116
98PhosphorylationKNLDVEATETGAPKE
CCCCEEECCCCCCCE		22.1527017623
100PhosphorylationLDVEATETGAPKELI
CCEEECCCCCCCEEE		34.0027017623
122PhosphorylationGLCGSIHSQLAKAVR
CCHHHHHHHHHHHHH		25.8127214570
142PhosphorylationQPNADIVTIGDKIKM
CCCCCEEECCHHHHH		21.4128889911
146AcetylationDIVTIGDKIKMQLLR
CEEECCHHHHHHHHH		38.7324489116
148AcetylationVTIGDKIKMQLLRTH
EECCHHHHHHHHHHC		26.7424489116
176PhosphorylationDAPTFQESALIADKL
CCCCHHHHHHHHHHH		20.0024909858
182AcetylationESALIADKLLSVMKA
HHHHHHHHHHHHHHH		42.1624489116
185PhosphorylationLIADKLLSVMKAGTY
HHHHHHHHHHHHCCC		30.5124909858
219AcetylationEKPIFNAKTIEQSPS
CCCCCCCEECEECCC		51.6524489116
224PhosphorylationNAKTIEQSPSFGKFE
CCEECEECCCCCEEE		15.1027717283
226PhosphorylationKTIEQSPSFGKFEID
EECEECCCCCEEEEC		52.4527214570
229AcetylationEQSPSFGKFEIDTDA
EECCCCCEEEECCCC		37.5024489116
284PhosphorylationAGDMINRYSILYNRT
HHHHHHHHHHHHHHH		8.7922369663
285PhosphorylationGDMINRYSILYNRTR
HHHHHHHHHHHHHHC		11.6822369663
288PhosphorylationINRYSILYNRTRQAV
HHHHHHHHHHHCCCH		10.8322369663
297PhosphorylationRTRQAVITNELVDII
HHCCCHHHHHHHHHH		18.9522369663
305PhosphorylationNELVDIITGASSLG-
HHHHHHHHCHHHCC-		27.3422369663
308PhosphorylationVDIITGASSLG----
HHHHHCHHHCC----		27.6922369663
309PhosphorylationDIITGASSLG-----
HHHHCHHHCC-----		36.2522369663
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ATPG_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ATPG_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ATPG_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CDC37_YEASTCDC37physical
16429126
RL10_YEASTRPL10physical
16429126
IF2A_YEASTSUI2physical
16429126
ATPB_YEASTATP2genetic
16339725
ARP3_YEASTARP3genetic
27708008
ERG3_YEASTERG3genetic
27708008
CDC7_YEASTCDC7genetic
27708008
GLE1_YEASTGLE1genetic
27708008
SLU7_YEASTSLU7genetic
27708008
TCPZ_YEASTCCT6genetic
27708008
GPI8_YEASTGPI8genetic
27708008
UTP5_YEASTUTP5genetic
27708008
TSC11_YEASTTSC11genetic
27708008
MOB2_YEASTMOB2genetic
27708008
ACT_YEASTACT1genetic
27708008
CDC14_YEASTCDC14genetic
27708008
PSA1_YEASTSCL1genetic
27708008
PRS8_YEASTRPT6genetic
27708008
RCC1_YEASTSRM1genetic
27708008
TEL2_YEASTTEL2genetic
27708008
RRP41_YEASTSKI6genetic
27708008
TIM44_YEASTTIM44genetic
27708008
CWC16_YEASTYJU2genetic
27708008
HYM1_YEASTHYM1genetic
27708008
CD123_YEASTCDC123genetic
27708008
ORC1_YEASTORC1genetic
27708008
TAF4_YEASTTAF4genetic
27708008
LCB1_YEASTLCB1genetic
27708008
DBP6_YEASTDBP6genetic
27708008
HRP1_YEASTHRP1genetic
27708008
XRN2_YEASTRAT1genetic
27708008
DIM1_YEASTDIM1genetic
27708008
PSB5_YEASTPRE2genetic
27708008
GEM1_YEASTGEM1genetic
27708008
RIM1_YEASTRIM1genetic
27708008
MTU1_YEASTSLM3genetic
27708008
QRI7_YEASTQRI7genetic
27708008
WWM1_YEASTWWM1genetic
27708008
YHH7_YEASTYSC83genetic
27708008
VPS13_YEASTVPS13genetic
27708008
AVL9_YEASTAVL9genetic
27708008
COQ11_YEASTYLR290Cgenetic
27708008
F16P_YEASTFBP1genetic
27708008
SWS2_YEASTSWS2genetic
27708008
HMI1_YEASTHMI1genetic
27708008
EXO1_YEASTEXO1genetic
27708008
RS10A_YEASTRPS10Agenetic
27708008
PMA2_YEASTPMA2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ATPG_YEAST

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Related Literatures of Post-Translational Modification

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