dbPTM

HYM1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HYM1_YEAST
UniProt AC	P32464
Protein Name	Protein HYM1
Gene Name	HYM1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	399
Subcellular Localization
Protein Description
Protein Sequence	MFKKYKNQDLDMAFWWKKNPKTPSDYARLIIEQLNKFSSPSLTQDNKRKVQEECTKYLIGTKHFIVGDTDPHPTPEAIDELYTAMHRADVFYELLLHFVDLEFEARRECMLIFSICLGYSKDNKFVTVDYLVSQPKTISLMLRTAEVALQQKGCQDIFLTVGNMIIECIKYEQLCRIILKDPQLWKFFEFAKLGNFEISTESLQILSAAFTAHPKLVSKEFFSNEINIIRFIKCINKLMAHGSYVTKRQSTKLLASLIVIRSNNALMNIYINSPENLKLIMTLMTDKSKNLQLEAFNVFKVMVANPRKSKPVFDILVKNRDKLLTYFKTFGLDSQDSTFLDEREFIVQEIDSLPRIISSTTEVSNNNASSSNVASITSPSSVMNNQSSILTHSTSPDSR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
380	Phosphorylation	VASITSPSSVMNNQS EEEECCCHHHHCCCC	35.02	28889911
388	Phosphorylation	SVMNNQSSILTHSTS HHHCCCCCCCCCCCC	16.32	19779198
391	Phosphorylation	NNQSSILTHSTSPDS CCCCCCCCCCCCCCC	16.47	19779198
393	Phosphorylation	QSSILTHSTSPDSR- CCCCCCCCCCCCCC-	25.91	19779198
395	Phosphorylation	SILTHSTSPDSR--- CCCCCCCCCCCC---	29.71	21440633
398	Phosphorylation	THSTSPDSR------ CCCCCCCCC------	43.18	21440633

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HYM1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HYM1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HYM1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PEX19_YEAST	PEX19	physical	11805837
KIC1_YEAST	KIC1	physical	11805837
ADH2_YEAST	ADH2	physical	11805837
UFD4_YEAST	UFD4	physical	11805837
FET3_YEAST	FET3	physical	11805837
KIC1_YEAST	KIC1	physical	12972564
SOG2_YEAST	SOG2	physical	12972564
RAS2_YEAST	RAS2	genetic	14871942
CCW12_YEAST	CCW12	genetic	15972461
SIM1_YEAST	SIM1	genetic	15972461
SRL1_YEAST	SRL1	genetic	15972461
ZRG8_YEAST	ZRG8	genetic	15972461
SSD1_YEAST	SSD1	genetic	12454058
BEM1_YEAST	BEM1	genetic	12454058
BEM2_YEAST	BEM2	genetic	12454058
BEM4_YEAST	BEM4	genetic	12454058
BST1_YEAST	BST1	genetic	12454058
GAS1_YEAST	GAS1	genetic	12454058
GOSR1_YEAST	GOS1	genetic	12454058
KRE1_YEAST	KRE1	genetic	12454058
NBP2_YEAST	NBP2	genetic	12454058
SAC7_YEAST	SAC7	genetic	12454058
CBK1_YEAST	CBK1	genetic	16552603
ACE2_YEAST	ACE2	genetic	15947194
DIG2_YEAST	DIG2	physical	18719252
DIG1_YEAST	DIG1	physical	18719252
ATG17_YEAST	ATG17	physical	18719252
SOG2_YEAST	SOG2	physical	18719252
KIC1_YEAST	KIC1	physical	18719252
MDV1_YEAST	MDV1	physical	18719252
CBK1_YEAST	CBK1	genetic	19967545
ACE2_YEAST	ACE2	genetic	19967545
XPO1_YEAST	CRM1	genetic	19967545
MOB2_YEAST	MOB2	genetic	15947194
KIC1_YEAST	KIC1	physical	24205201
TRI27_HUMAN	TRIM27	physical	27107014
IFIT3_HUMAN	IFIT3	physical	27107014
LZTS2_HUMAN	LZTS2	physical	27107014
GOGA2_HUMAN	GOLGA2	physical	27107014
CQ053_HUMAN	C17orf53	physical	27107014
SPERT_HUMAN	SPERT	physical	27107014
TRI55_HUMAN	TRIM55	physical	27107014
TRI69_HUMAN	TRIM69	physical	27107014

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HYM1_YEAST

Related Literatures of Post-Translational Modification