| UniProt ID | CD123_YEAST | |
|---|---|---|
| UniProt AC | Q05791 | |
| Protein Name | Cell division cycle protein 123 | |
| Gene Name | CDC123 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 360 | |
| Subcellular Localization | Cytoplasm . | |
| Protein Description | Regulates the cell cycle in a nutrient dependent manner. Accumulates in presence of nutrients and directs the destabilization of DMA1 and DMA2, whose accumulation results in a G1 block. Regulates also the abundance of GCD11 an essential component of the translational initiation factor 2.. | |
| Protein Sequence | MSSQEYTTFIDIPVTRAQVEHCSYSFWSSLYPKYVPKSIVLKSLPKKFIQYLEQDGIKLPQEENSRSVYTEEIIRNEDNDYSDWEDDEDTATEFVQEVEPLIDFPELHQKLKDALNELGAVAPKLNWSAPRDATWILPNNTMKCNEVNELYLLLNASNYIMHDLQRAFKGCVDGDDIKGLKFDLVLRQWCDMNPALEFRVFVKNAHIVGATQRDLNYYDYLDELSDTFKDLIDEIVHDVVLPKFPDKSFVLDVYIPRPFNKIFIVDINPFARKTDSLLFSWNEIAAIAPPKNDVEDYELRLVTRHNTGRFASKEHSENHVPQDLVEASLNPEAIRELTQKWKELLSQQAKEESSDSENET | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSSQEYTTF ------CCCCCEEEE | 40.50 | 30377154 | |
| 6 | Phosphorylation | --MSSQEYTTFIDIP --CCCCCEEEEEECC | 11.93 | 30377154 | |
| 8 | Phosphorylation | MSSQEYTTFIDIPVT CCCCCEEEEEECCCC | 20.07 | 30377154 | |
| 65 | Phosphorylation | KLPQEENSRSVYTEE CCCCCCCCCCCCHHH | 29.25 | 19823750 | |
| 67 | Phosphorylation | PQEENSRSVYTEEII CCCCCCCCCCHHHHH | 21.21 | 19823750 | |
| 69 | Phosphorylation | EENSRSVYTEEIIRN CCCCCCCCHHHHHCC | 15.07 | 19823750 | |
| 70 | Phosphorylation | ENSRSVYTEEIIRNE CCCCCCCHHHHHCCC | 25.61 | 19823750 | |
| 81 | Phosphorylation | IRNEDNDYSDWEDDE HCCCCCCCCCCCCCC | 18.13 | 19823750 | |
| 82 | Phosphorylation | RNEDNDYSDWEDDED CCCCCCCCCCCCCCC | 38.83 | 28747907 | |
| 90 | Phosphorylation | DWEDDEDTATEFVQE CCCCCCCHHHHHHHH | 33.17 | 19823750 | |
| 92 | Phosphorylation | EDDEDTATEFVQEVE CCCCCHHHHHHHHHH | 31.86 | 19823750 | |
| 346 | Phosphorylation | QKWKELLSQQAKEES HHHHHHHHHHHHHHC | 32.63 | 19795423 | |
| 353 | Phosphorylation | SQQAKEESSDSENET HHHHHHHCCCCCCCC | 40.30 | 22369663 | |
| 354 | Phosphorylation | QQAKEESSDSENET- HHHHHHCCCCCCCC- | 48.73 | 22369663 | |
| 356 | Phosphorylation | AKEESSDSENET--- HHHHCCCCCCCC--- | 44.24 | 22369663 | |
| 360 | Phosphorylation | SSDSENET------- CCCCCCCC------- | 56.33 | 22369663 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CD123_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CD123_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CD123_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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