OM14_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: OM14_YEAST
• UniProt AC: P38325
• Protein Name: Mitochondrial outer membrane protein OM14
• Gene Name: OM14
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 134
• Subcellular Localization: Mitochondrion outer membrane ; Multi-pass membrane protein .
• Protein Sequence: MSATAKHDSNASPNSDSEDGHHHNNKKECAIEYLKARLNSASAVACGYLQAFVSKTQDFAKVCFLELQNPVVLVNLLLHSSVVCYLCNGYANHNARFLKGKPNSTVLATTAGALGLLTLDGIISKKYYSRYDKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	SATAKHDSNASPNSD CCCCCCCCCCCCCCC	33.73	29136822
12	Phosphorylation	AKHDSNASPNSDSED CCCCCCCCCCCCCCC	28.94	17287358
15	Phosphorylation	DSNASPNSDSEDGHH CCCCCCCCCCCCCCC	45.99	19823750
17	Phosphorylation	NASPNSDSEDGHHHN CCCCCCCCCCCCCCC	37.09	29136822
26	Acetylation	DGHHHNNKKECAIEY CCCCCCCHHHHHHHH	56.09	25381059
35	Acetylation	ECAIEYLKARLNSAS HHHHHHHHHHHHHHH	30.47	24489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of OM14_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of OM14_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of OM14_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MIM1_YEAST	MIM1	physical	21825073
VDAC1_YEAST	POR1	physical	22461620
ATPA_YEAST	ATP1	physical	22461620
ATPB_YEAST	ATP2	physical	22461620
ATPG_YEAST	ATP3	physical	22461620
ATP7_YEAST	ATP7	physical	22461620
QCR1_YEAST	COR1	physical	22461620
CY1_YEAST	CYT1	physical	22461620
NDH1_YEAST	NDE1	physical	22461620
QCR2_YEAST	QCR2	physical	22461620
MPCP_YEAST	MIR1	physical	22461620
ADT2_YEAST	PET9	physical	22461620
SFC1_YEAST	SFC1	physical	22461620
YHM2_YEAST	YHM2	physical	22461620
PHB2_YEAST	PHB2	physical	22461620
ATC6_YEAST	SPF1	physical	22461620
RL13A_YEAST	RPL13A	physical	22461620
RL21A_YEAST	RPL21A	physical	22461620
RS14A_YEAST	RPS14A	physical	22461620
OM14_YEAST	OM14	physical	22461620
OM45_YEAST	OM45	physical	22461620
HSP72_YEAST	SSA2	physical	22940862
HSP71_YEAST	SSA1	physical	22940862
NACB1_YEAST	EGD1	physical	25487825
NACA_YEAST	EGD2	physical	25487825
MRM2_YEAST	MRM2	genetic	27708008
SWI6_YEAST	SWI6	genetic	27708008
INO4_YEAST	INO4	genetic	27708008
CSG2_YEAST	CSG2	genetic	27708008
ELO2_YEAST	ELO2	genetic	27708008
ARO1_YEAST	ARO1	genetic	27708008
AROC_YEAST	ARO2	genetic	27708008
MED5_YEAST	NUT1	genetic	27708008
NAM8_YEAST	NAM8	genetic	27708008
IMPX_YEAST	IMP2	genetic	27708008
ASF1_YEAST	ASF1	genetic	27708008
YKH5_YEAST	YKL075C	genetic	27708008
DCOR_YEAST	SPE1	genetic	27708008
SAC1_YEAST	SAC1	genetic	27708008
UTH1_YEAST	UTH1	genetic	27708008
SOK2_YEAST	SOK2	genetic	27708008
PKR1_YEAST	PKR1	genetic	27708008
NST1_YEAST	NST1	genetic	27708008
ATX2_YEAST	ATX2	genetic	27708008
SNU66_YEAST	SNU66	genetic	27708008
CHMU_YEAST	ARO7	genetic	27708008
SPEE_YEAST	SPE3	genetic	27708008
MRL1_YEAST	MRL1	genetic	27708008
MDM36_YEAST	MDM36	genetic	27708008
SAM37_YEAST	SAM37	physical	28109174
TOM70_YEAST	TOM70	physical	28109174

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Analysis of phosphorylation sites on proteins from Saccharomycescerevisiae by electron transfer dissociation (ETD) massspectrometry.";
Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.;
Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-12 AND SER-15, AND MASSSPECTROMETRY.
PubMed: 17287358