SFC1_YEAST - dbPTM
SFC1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SFC1_YEAST
UniProt AC P33303
Protein Name Succinate/fumarate mitochondrial transporter
Gene Name SFC1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 322
Subcellular Localization Mitochondrion inner membrane
Multi-pass membrane protein.
Protein Description Transports cytoplasmic succinate, derived from isocitrate by the action of isocitrate lyase in the cytosol, into the mitochondrial matrix in exchange for fumarate..
Protein Sequence MSQKKKASHPAINLMAGGTAGLFEALCCHPLDTIKVRMQIYRRVAGIEHVKPPGFIKTGRTIYQKEGFLALYKGLGAVVIGIIPKMAIRFSSYEFYRTLLVNKESGIVSTGNTFVAGVGAGITEAVLVVNPMEVVKIRLQAQHLTPSEPNAGPKYNNAIHAAYTIVKEEGVSALYRGVSLTAARQATNQGANFTVYSKLKEFLQNYHQMDVLPSWETSCIGLISGAIGPFSNAPLDTIKTRLQKDKSISLEKQSGMKKIITIGAQLLKEEGFRALYKGITPRVMRVAPGQAVTFTVYEYVREHLENLGIFKKNDTPKPKPLK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
147PhosphorylationQAQHLTPSEPNAGPK
EECCCCCCCCCCCCC		61.5227214570
252AcetylationDKSISLEKQSGMKKI
CCCCCCHHHHCCCHH		55.8725381059
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SFC1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SFC1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SFC1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PEX22_YEASTPEX22genetic
20093466
DEP1_YEASTDEP1genetic
20093466
YSW1_YEASTYSW1genetic
20093466
AIM4_YEASTAIM4genetic
20093466
GDIR_YEASTRDI1genetic
20093466
SNF6_YEASTSNF6genetic
20093466
PDX3_YEASTPDX3genetic
21623372
AATC_YEASTAAT2genetic
21623372
IDH2_YEASTIDH2genetic
21623372
IDH1_YEASTIDH1genetic
21623372
SYSM_YEASTDIA4genetic
21623372
PFKA1_YEASTPFK1genetic
21623372
QCR2_YEASTQCR2genetic
21623372
SSB1_YEASTSSB1physical
22940862
HSP71_YEASTSSA1physical
22940862
HSP72_YEASTSSA2physical
22940862
PEX22_YEASTPEX22genetic
27708008
AIM4_YEASTAIM4genetic
27708008
MRM2_YEASTMRM2genetic
27708008
MED5_YEASTNUT1genetic
27708008
SNF6_YEASTSNF6genetic
27708008
IDH2_YEASTIDH2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SFC1_YEAST

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Related Literatures of Post-Translational Modification

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