SYSM_YEAST - dbPTM
SYSM_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SYSM_YEAST
UniProt AC P38705
Protein Name Serine--tRNA ligase, mitochondrial
Gene Name DIA4
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 446
Subcellular Localization Mitochondrion matrix .
Protein Description Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)..
Protein Sequence MIIRRLFSISNRSFFLKKPQFDVKKIIEMIPQYQTSIQNRELIEADSIIRSLQLLGERYQNIKEIDKVIADIQIQRKSIEAQIKKDKTKITEYSAALKALKEQYNDQNSKSSELKKKILETCKSLPNTLDPTVPLDAPQIEQWINPLKTHKTSEAQAHVDIMLKKNMLDLQTASNVTGMSWYYLLNDGARLEQALVAYALKKANENGFSSCVPPSITKKELIDACGFNPRDMNNERQIYALQDTNLGLVATAEIPLAGLGANKVLELNSGECSKKLVGVSRCYRAEAGARGKDTKGLYRVHEFTKVELFCWSKPETSAKVLEEIKQFQISVVEELGIPAKVLNMPSNDLGNPAFKKYDIEAWMPGRGKFGEISSASNCTDFQSRRLNTKYRDDNTGKLEYVHTLNGTAMAIPRVIVALVENFYDPSTGKISVPECLREFMNGQRYI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of SYSM_YEAST !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SYSM_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SYSM_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SYSM_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SWC3_YEASTSWC3physical
22875988
KIN3_YEASTKIN3physical
22875988
PAM1_YEASTPAM1physical
22875988
SUM1_YEASTSUM1physical
22875988
SNX41_YEASTSNX41physical
22875988
SPC25_YEASTSPC25physical
22875988
GCN20_YEASTGCN20physical
22875988
NNF2_YEASTNNF2physical
22875988
OKP1_YEASTOKP1physical
22875988
SAE3_YEASTSAE3physical
22875988
LAM4_YEASTYHR080Cphysical
22875988
NNF1_YEASTNNF1physical
22875988
CASP_YEASTCOY1physical
22875988
NTR2_YEASTNTR2physical
22875988
PFD6_YEASTYKE2physical
22875988
STB2_YEASTSTB2physical
22875988
STV1_YEASTSTV1physical
22875988
VPS20_YEASTVPS20physical
22875988
SPC24_YEASTSPC24physical
22875988
NUF2_YEASTNUF2physical
22875988
RGA1_YEASTRGA1physical
22875988
SVL3_YEASTSVL3physical
22875988
TBP6_YEASTYTA6physical
22875988
GYP5_YEASTGYP5physical
22875988
HDA2_YEASTHDA2physical
22875988
SLK19_YEASTSLK19physical
22875988
TCPD_YEASTCCT4genetic
27708008
SMP3_YEASTSMP3genetic
27708008
STU1_YEASTSTU1genetic
27708008
PRP6_YEASTPRP6genetic
27708008
MED8_YEASTMED8genetic
27708008
GLE1_YEASTGLE1genetic
27708008
MAK21_YEASTMAK21genetic
27708008
STN1_YEASTSTN1genetic
27708008
CAB5_YEASTCAB5genetic
27708008
TSC11_YEASTTSC11genetic
27708008
GNA1_YEASTGNA1genetic
27708008
MOB2_YEASTMOB2genetic
27708008
PSA1_YEASTSCL1genetic
27708008
PRS8_YEASTRPT6genetic
27708008
RCC1_YEASTSRM1genetic
27708008
TEL2_YEASTTEL2genetic
27708008
MET30_YEASTMET30genetic
27708008
DPOD2_YEASTPOL31genetic
27708008
CDC11_YEASTCDC11genetic
27708008
SWD2_YEASTSWD2genetic
27708008
SEC22_YEASTSEC22genetic
27708008
TPT1_YEASTTPT1genetic
27708008
HRP1_YEASTHRP1genetic
27708008
XRN2_YEASTRAT1genetic
27708008
DYR_YEASTDFR1genetic
27708008
CLP1_YEASTCLP1genetic
27708008
SYH_YEASTHTS1genetic
27708008
PSB5_YEASTPRE2genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SYSM_YEAST

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Related Literatures of Post-Translational Modification

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