dbPTM

YKH5_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YKH5_YEAST
UniProt AC	P36083
Protein Name	Uncharacterized protein YKL075C
Gene Name	YKL075C
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	450
Subcellular Localization
Protein Description
Protein Sequence	MAKDLLPKQAANEPSLKDCTCKRCLKLGASKEKKIRRKKKGEEKRERHYGNRRKLTFNFLKHTNMENTNYDVITSVGYLNEKYGLKKSHYIEKFIKCIHRKINIDVSKITDAYVNSLNPWVKVKLFLLLVTLSEKGGPEYWLDKTDGEKNSEASSTDNSLENSTKGADSAGSTALRDEMVKSHKNLFPTLTEQIIQHNINQDFTESTYDEDYVFSSIWANFMEGLINHYLEKVIVPYSEMKVCQQLYKPMMKIISLYNEYNELMVKSEKNGFLPSLQDSENVQGDKGEKESKDDAVSQERLERAQKLLWQAREDIPKTISKELTLLSEMYSTLSADEQDYELDEFVCCAEEYIELEYLPALVDVLFANCGTNNFWKIMLVLEPFFYYIEDVGGDDDEDEDNVDNSEGDEESLLSRNVEGDDNVVERHFKPDPRVITLEKICEVAARQKWI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
90	Phosphorylation	YGLKKSHYIEKFIKC HCCCHHHHHHHHHHH	20.19	28889911
93	Acetylation	KKSHYIEKFIKCIHR CHHHHHHHHHHHHHH	42.71	24489116
140	Phosphorylation	SEKGGPEYWLDKTDG HHCCCCCCEEECCCC	17.88	28889911
145	Phosphorylation	PEYWLDKTDGEKNSE CCCEEECCCCCCCCC	49.23	28889911
154	Phosphorylation	GEKNSEASSTDNSLE CCCCCCCCCCCCCCC	29.71	28889911
155	Phosphorylation	EKNSEASSTDNSLEN CCCCCCCCCCCCCCC	46.99	23749301
156	Phosphorylation	KNSEASSTDNSLENS CCCCCCCCCCCCCCC	36.38	25752575
172	Phosphorylation	KGADSAGSTALRDEM CCCCCCCCHHHHHHH	15.38	28889911
297	Phosphorylation	ESKDDAVSQERLERA CCCCCHHHHHHHHHH	28.22	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YKH5_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YKH5_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YKH5_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FBRL_YEAST	NOP1	physical	16554755
YRA1_YEAST	YRA1	physical	16554755
NST1_YEAST	NST1	physical	16554755
IBD2_YEAST	IBD2	physical	16554755
NST1_YEAST	NST1	physical	18719252
MDM34_YEAST	MDM34	genetic	27708008
GGPPS_YEAST	BTS1	genetic	27708008
APC11_YEAST	APC11	genetic	27708008
CDC37_YEAST	CDC37	genetic	27708008
ACT_YEAST	ACT1	genetic	27708008
PSA7_YEAST	PRE10	genetic	27708008
RPN7_YEAST	RPN7	genetic	27708008
MED10_YEAST	NUT2	genetic	27708008
UFD2_YEAST	UFD2	genetic	27708008
HSP42_YEAST	HSP42	genetic	27708008
PMP3_YEAST	PMP3	genetic	27708008
XRS2_YEAST	XRS2	genetic	27708008
MED5_YEAST	NUT1	genetic	27708008
HUR1_YEAST	HUR1	genetic	27708008
SMI1_YEAST	SMI1	genetic	27708008
FIS1_YEAST	FIS1	genetic	27708008
ICE2_YEAST	ICE2	genetic	27708008
RCY1_YEAST	RCY1	genetic	27708008
CSN12_YEAST	YJR084W	genetic	27708008
ILM1_YEAST	ILM1	genetic	27708008
RHO4_YEAST	RHO4	genetic	27708008
RT109_YEAST	RTT109	genetic	27708008
CHS5_YEAST	CHS5	genetic	27708008
VID22_YEAST	VID22	genetic	27708008
DUS3_YEAST	DUS3	genetic	27708008
SOK2_YEAST	SOK2	genetic	27708008
PALI_YEAST	RIM9	genetic	27708008
IRA2_YEAST	IRA2	genetic	27708008
RRP6_YEAST	RRP6	genetic	27708008
GLO4_YEAST	GLO4	genetic	27708008
YO062_YEAST	YOR062C	genetic	27708008
WHI5_YEAST	WHI5	genetic	27708008
VPS17_YEAST	VPS17	genetic	27708008
PALA_YEAST	RIM20	genetic	27708008
RS10A_YEAST	RPS10A	genetic	27708008
NIP80_YEAST	NIP100	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YKH5_YEAST

Related Literatures of Post-Translational Modification