CCW14_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CCW14_YEAST
• UniProt AC: O13547
• Protein Name: Covalently-linked cell wall protein 14
• Gene Name: CCW14
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 238
• Subcellular Localization: Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Covalently-linked GPI-modified cell wall protein (GPI-CWP).
• Protein Description: Component of the inner layer of the cell wall..
• Protein Sequence: MRATTLLSSVVSLALLSKEVLATPPACLLACVAQVGKSSSTCDSLNQVTCYCEHENSAVKKCLDSICPNNDADAAYSAFKSSCSEQNASLGDSSSSASSSASSSSKASSSTKASSSSASSSTKASSSSASSSTKASSSSAAPSSSKASSTESSSSSSSSTKAPSSEESSSTYVSSSKQASSTSEAHSSSAASSTVSQETVSSALPTSTAVISTFSEGSGNVLEAGKSVFIAAVAAMLI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	RATTLLSSVVSLALL CHHHHHHHHHHHHHH	26.89	28889911
17	Phosphorylation	VVSLALLSKEVLATP HHHHHHHCCHHHCCC	27.85	28889911
61	Acetylation	HENSAVKKCLDSICP CCCHHHHHHHHHHCC	33.17	24489116
65	Phosphorylation	AVKKCLDSICPNNDA HHHHHHHHHCCCCCH	17.09	28132839
87	N-linked_Glycosylation	KSSCSEQNASLGDSS HHHHHHHCCCCCCCC	27.69	-
114	Phosphorylation	ASSSTKASSSSASSS CCCCCCCCCCCCCCC	32.10	19779198
115	Phosphorylation	SSSTKASSSSASSST CCCCCCCCCCCCCCC	32.92	19779198
119	Phosphorylation	KASSSSASSSTKASS CCCCCCCCCCCCCCC	27.11	19779198
126	Phosphorylation	SSSTKASSSSASSST CCCCCCCCCCCCCCC	32.92	19779198
130	Phosphorylation	KASSSSASSSTKASS CCCCCCCCCCCCCCC	27.11	19779198
134	Ubiquitination	SSASSSTKASSSSAA CCCCCCCCCCCCCCC	48.49	23749301
144	Phosphorylation	SSSAAPSSSKASSTE CCCCCCCCCCCCCCC	34.50	19779198
146	Ubiquitination	SAAPSSSKASSTESS CCCCCCCCCCCCCCC	54.99	23749301
161	Ubiquitination	SSSSSSTKAPSSEES CCCCCCCCCCCCCCC	61.31	22106047
217	GPI-anchor	VISTFSEGSGNVLEA EEEEECCCCCCHHHH	39.39	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CCW14_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CCW14_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CCW14_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GAS1_YEAST	GAS1	genetic	16269340
NEM1_YEAST	NEM1	genetic	16269340
RIC1_YEAST	RIC1	genetic	16269340
BGL2_YEAST	BGL2	physical	22940862
GAS1_YEAST	GAS1	genetic	23891562
RPN4_YEAST	RPN4	genetic	27708008
VAM7_YEAST	VAM7	genetic	27708008
RL17B_YEAST	RPL17B	genetic	27708008
SIW14_YEAST	SIW14	genetic	27708008
MKT1_YEAST	MKT1	genetic	27708008
YBS1_YEAST	YBR071W	genetic	27708008
UBC4_YEAST	UBC4	genetic	27708008
CCZ1_YEAST	CCZ1	genetic	27708008
SGF29_YEAST	SGF29	genetic	27708008
SLX5_YEAST	SLX5	genetic	27708008
OST4_YEAST	OST4	genetic	27708008
SWF1_YEAST	SWF1	genetic	27708008
SWI5_YEAST	SWI5	genetic	27708008
MED5_YEAST	NUT1	genetic	27708008
XRN1_YEAST	XRN1	genetic	27708008
ICE2_YEAST	ICE2	genetic	27708008
YJ90_YEAST	YJR120W	genetic	27708008
FEN1_YEAST	RAD27	genetic	27708008
DNM1_YEAST	DNM1	genetic	27708008
RL22A_YEAST	RPL22A	genetic	27708008
PKR1_YEAST	PKR1	genetic	27708008
PFKA2_YEAST	PFK2	genetic	27708008
TDA1_YEAST	TDA1	genetic	27708008
NST1_YEAST	NST1	genetic	27708008
PHO23_YEAST	PHO23	genetic	27708008
BRE5_YEAST	BRE5	genetic	27708008
BUB3_YEAST	BUB3	genetic	27708008
BUD21_YEAST	BUD21	genetic	27708008
DDP1_YEAST	DDP1	genetic	27708008
TBP6_YEAST	YTA6	genetic	27708008
HSP7F_YEAST	SSE1	genetic	27708008
AIM44_YEAST	AIM44	genetic	27708008
CG12_YEAST	CLN2	genetic	27708008
ROX1_YEAST	ROX1	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.