| UniProt ID | ROX1_YEAST | |
|---|---|---|
| UniProt AC | P25042 | |
| Protein Name | Repressor ROX1 | |
| Gene Name | ROX1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 368 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Transcription factor that represses the expression of HEM13, COX5B, ANB1, CYC7 or AAC3 (hypoxic function). Binds to the DNA sequence 5'-RRRTAACAAGAG-3'.. | |
| Protein Sequence | MNPKSSTPKIPRPKNAFILFRQHYHRILIDEWTAQGVEIPHNSNISKIIGTKWKGLQPEDKAHWENLAEKEKLEHERKYPEYKYKPVRKSKKKQLLLKEIEQQQQQQQKEQQQQKQSQPQLQQPFNNNIVLMKRAHSLSPSSSVSSSNSYQFQLNNDLKRLPIPSVNTSNYMVSRSLSGLPLTHDKTARDLPQLSSQLNSIPYYSAPHDPSTRHHYLNVAQAQPRANSTPQLPFISSIINNSSQTPVTTTTTSTTTATSSPGKFSSSPNSSVLENNRLNSINNSNQYLPPPLLPSLQDFQLDQYQQLKQMGPTYIVKPLSHTRNNLLSTTTPTHHHIPHIPNQNIPLHQIINSSNTEVTAKTSLVSPK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 5 | Phosphorylation | ---MNPKSSTPKIPR ---CCCCCCCCCCCC | 40.47 | 28889911 | |
| 7 | Phosphorylation | -MNPKSSTPKIPRPK -CCCCCCCCCCCCCC | 35.37 | 30377154 | |
| 137 | Phosphorylation | VLMKRAHSLSPSSSV EEEEECEECCCCCCC | 29.56 | 24961812 | |
| 139 | Phosphorylation | MKRAHSLSPSSSVSS EEECEECCCCCCCCC | 26.25 | 24961812 | |
| 141 | Phosphorylation | RAHSLSPSSSVSSSN ECEECCCCCCCCCCC | 31.69 | 24961812 | |
| 142 | Phosphorylation | AHSLSPSSSVSSSNS CEECCCCCCCCCCCC | 37.84 | 24961812 | |
| 143 | Phosphorylation | HSLSPSSSVSSSNSY EECCCCCCCCCCCCE | 30.29 | 24961812 | |
| 145 | Phosphorylation | LSPSSSVSSSNSYQF CCCCCCCCCCCCEEE | 29.96 | 24961812 | |
| 176 | Phosphorylation | SNYMVSRSLSGLPLT CCCEEEECCCCCCCC | 21.27 | 22369663 | |
| 178 | Phosphorylation | YMVSRSLSGLPLTHD CEEEECCCCCCCCCC | 39.26 | 22369663 | |
| 265 | Phosphorylation | TSSPGKFSSSPNSSV CCCCCCCCCCCCCHH | 33.13 | 22369663 | |
| 266 | Phosphorylation | SSPGKFSSSPNSSVL CCCCCCCCCCCCHHH | 53.61 | 22369663 | |
| 267 | Phosphorylation | SPGKFSSSPNSSVLE CCCCCCCCCCCHHHC | 27.23 | 22369663 | |
| 270 | Phosphorylation | KFSSSPNSSVLENNR CCCCCCCCHHHCCCC | 25.80 | 22369663 | |
| 271 | Phosphorylation | FSSSPNSSVLENNRL CCCCCCCHHHCCCCC | 37.04 | 22369663 | |
| 363 | Phosphorylation | TEVTAKTSLVSPK-- CEEEEEEECCCCC-- | 26.52 | 30377154 | |
| 366 | Phosphorylation | TAKTSLVSPK----- EEEEECCCCC----- | 32.06 | 21440633 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ROX1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ROX1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ROX1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-176, AND MASSSPECTROMETRY. | |
