QDR3_YEAST - dbPTM
QDR3_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID QDR3_YEAST
UniProt AC P38227
Protein Name Quinidine resistance protein 3
Gene Name QDR3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 689
Subcellular Localization Cell membrane
Multi-pass membrane protein .
Protein Description Multidrug resistance transporter involved in resistance and adaptation to quinidine and to the herbicide barban (4-chloro-2-butynyl [3-chlorophenyl] carbamate)..
Protein Sequence MQAQGSQSNVGSLRSNCSDNSLPNNHVMMHCDESSGSPHSEHNDYSYEKTNLESTASNSREHRDNQLSRLKSEEYVVPKNQRRGLLPQLAIIPEFKDARDYPPMMKKMIVFLIAFSSMMGPMGTSIIFPAINSITTEFKTSVIMVNVSIGVYLLSLGVFPLWWSSLSELEGRRTTYITSFALLFAFNIGSALAPDINSFIALRMLCGAASASVQSVGAGTVADLYISEDRGKNLSYYYLGPLLAPLLSPIFGSLLVNRWPWRSTQWFMVILSGCNVILLTVLLPETLRKQDSKGAIAQILAERRIQVDNNERGEIQEDYQRGEDETDRIENQVATLSTEKHNYVGEVRDQDSLDLESHSSPNTYDGRAGETQLQRIYTEASRSLYEYQLDDSGIDATTAQVTRIRSTDPKLARSIRENSLRKLQTNLEEQVKKVLSSNGGEIAPKQVSAVRKVWDTFFVYFIKPLKSLHFLEYPPVALAITFSAISFSTVYFVNMTVEYKYSRPPYNFKPLYIGLLYIPNSVTYFFASIYGGRWVDMLLKRYKEKYGILAPEARISWNVVTSVISFPIALLIFGWCLDKKCHWVTPLIGTALFGYAAMMTIGATLSYLVDSLPGKGATGVALNNLIRQILAATAVFVTTPMLNGMGTGWAFTMLAFIVLGASSVLIILKKHGDYWRENYDLQKLYDKID
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
50PhosphorylationNDYSYEKTNLESTAS
CCCCCCCCCCCCCCC		32.8521126336
54PhosphorylationYEKTNLESTASNSRE
CCCCCCCCCCCCCHH		32.2324961812
55PhosphorylationEKTNLESTASNSREH
CCCCCCCCCCCCHHH		25.4028889911
57PhosphorylationTNLESTASNSREHRD
CCCCCCCCCCHHHHC		35.1125533186
59PhosphorylationLESTASNSREHRDNQ
CCCCCCCCHHHHCHH		36.2328889911
72PhosphorylationNQLSRLKSEEYVVPK
HHHHHCCCCCCCCCH		40.0123749301
326PhosphorylationYQRGEDETDRIENQV
HHCCCCHHHHHHHHH		42.7928889911
340UbiquitinationVATLSTEKHNYVGEV
HHCCCCCCCCCCCCC		36.9223749301
352PhosphorylationGEVRDQDSLDLESHS
CCCCCCCCCCCCCCC		20.3923749301
359PhosphorylationSLDLESHSSPNTYDG
CCCCCCCCCCCCCCC		57.6927214570
371PhosphorylationYDGRAGETQLQRIYT
CCCCCCHHHHHHHHH		33.3928889911
378PhosphorylationTQLQRIYTEASRSLY
HHHHHHHHHHHHHHE		23.7819779198
381PhosphorylationQRIYTEASRSLYEYQ
HHHHHHHHHHHEEEE		19.0319779198
383PhosphorylationIYTEASRSLYEYQLD
HHHHHHHHHEEEECC		32.5719779198
385PhosphorylationTEASRSLYEYQLDDS
HHHHHHHEEEECCCC		17.5219779198
392PhosphorylationYEYQLDDSGIDATTA
EEEECCCCCCCCCCE		37.0027017623
422AcetylationIRENSLRKLQTNLEE
HHHHHHHHHHHCHHH		50.6817397211
425PhosphorylationNSLRKLQTNLEEQVK
HHHHHHHHCHHHHHH		52.8124930733
436PhosphorylationEQVKKVLSSNGGEIA
HHHHHHHHCCCCCCC		25.4128152593
437PhosphorylationQVKKVLSSNGGEIAP
HHHHHHHCCCCCCCH		35.0223749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of QDR3_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of QDR3_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of QDR3_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PDR12_YEASTPDR12physical
18467557
CHO2_YEASTCHO2physical
16093310
TOR2_YEASTTOR2genetic
20526336
YCZ2_YEASTYCR102Cgenetic
27708008
PP2C1_YEASTPTC1genetic
27708008
SLX5_YEASTSLX5genetic
27708008
RLA1_YEASTRPP1Agenetic
27708008
TFS2_YEASTDST1genetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
CY1_YEASTCYT1genetic
27708008
WHI5_YEASTWHI5genetic
27708008
MET8_YEASTMET8genetic
27708008
RV161_YEASTRVS161genetic
27708008
PER1_YEASTPER1genetic
27708008
PUT2_YEASTPUT2genetic
27708008
MED20_YEASTSRB2genetic
27708008
DAL81_YEASTDAL81genetic
27708008
SMY1_YEASTSMY1genetic
27708008
KTI12_YEASTKTI12genetic
27708008
MEH1_YEASTMEH1genetic
27708008
TPO1_YEASTTPO1genetic
27708008
ACE2_YEASTACE2genetic
27708008
PEX12_YEASTPEX12genetic
27708008
CMC1_YEASTSAL1genetic
27708008
PDR10_YEASTPDR10genetic
27708008
FRE3_YEASTFRE3genetic
27708008
KES1_YEASTKES1genetic
27708008
FUMH_YEASTFUM1genetic
27708008
KAR3_YEASTKAR3genetic
27708008
NPR3_YEASTNPR3genetic
29674565
LST8_YEASTLST8genetic
29674565
WDR59_YEASTMTC5genetic
29674565
CDC23_YEASTCDC23genetic
29674565
FUMH_YEASTFUM1genetic
29674565
ORC4_YEASTORC4genetic
29674565
THRC_YEASTTHR4genetic
29674565
SWR1_YEASTSWR1genetic
29674565
LSM6_YEASTLSM6genetic
29674565
GET2_YEASTGET2genetic
29674565
RL11B_YEASTRPL11Bgenetic
29674565
NMD2_YEASTNMD2genetic
29674565
RPE_YEASTRPE1genetic
29674565
HIR3_YEASTHIR3genetic
29674565
SIC1_YEASTSIC1genetic
29674565
RS30A_YEASTRPS30Agenetic
29674565
RS30B_YEASTRPS30Agenetic
29674565
NIP80_YEASTNIP100genetic
29674565
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of QDR3_YEAST

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-57, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory