AIM14_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AIM14_YEAST
• UniProt AC: P53109
• Protein Name: Probable metalloreductase AIM14
• Gene Name: AIM14
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 570
• Subcellular Localization: Membrane; Multi-pass membrane protein.
• Protein Description: Probable cell surface metalloreductase. May be involved in iron or copper homeostasis (By similarity)..
• Protein Sequence: MKESPLITLVKRHSETHFANIKYGYYVLIISLVYLIGLALLRAFGRRTPSRSSSAFKNKIIYRLYDIDPAIHLGILFFAVLIPFYYHYSLTTQSTVYLKRLGRLSYALIPLNLFLTLRPNWFLRKNCTYTDFIPFHKWFSRIITVIGLLHGIFFIIKWAIDDNVSLKQKLILKTFNFAGFIISILVLFLLICSIGPMRRYNYRLFYIVHNLVNVAFILLTPIHSRPGVKFPFLLLNCTLLFIHIINRIVFAKSLMILNKNANYSKTNLVHVRLPRAILPDYFEPGSHIRISPYRRINPLYWLLPSHPYTIASLAEDNSIDLIIKETSTAEPGSQIESLRSNPKSFHLDQEKTYTLINSYPPSVPEECYSQGTNIAIICGGSGISFALPLFRHFFNKENVKYLKMIWLIKDYSEYELVLDYLKTNGLTFEKKLSNNKRISVFISGEYTAETRLDEITTNIDDENSEYEMGSFNNEDEDLSISNFNSENADSNDNTPETSHSPTKENGSMIEVKSKHSFTLSNELKSFNNESAQVNQNETWLFSCGPPSLLQLSKKYCNDERINFVCETYGL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
433	Phosphorylation	LTFEKKLSNNKRISV CCEEEECCCCCCEEE	47.43	28889911
507	Phosphorylation	SPTKENGSMIEVKSK CCCCCCCCEEEEEEC	28.33	27717283

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AIM14_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AIM14_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AIM14_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HAP3_YEAST	HAP3	genetic	20093466
PAT1_YEAST	PAT1	genetic	20093466
SLX5_YEAST	SLX5	genetic	20093466
YOR1_YEAST	YOR1	genetic	20093466
IML2_YEAST	IML2	genetic	20093466
ARP6_YEAST	ARP6	genetic	20093466
VAC14_YEAST	VAC14	genetic	20093466
INO4_YEAST	INO4	genetic	20093466
SUR1_YEAST	SUR1	genetic	20093466
CHL1_YEAST	CHL1	genetic	20093466
YP089_YEAST	YPR089W	genetic	20093466
MCA1_YEAST	MCA1	genetic	22586098
VPS53_YEAST	VPS53	genetic	27708008
RS21B_YEAST	RPS21B	genetic	27708008
SUR1_YEAST	SUR1	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.