JSN1_YEAST - dbPTM
JSN1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID JSN1_YEAST
UniProt AC P47135
Protein Name Protein JSN1
Gene Name JSN1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 1091
Subcellular Localization
Protein Description
Protein Sequence MDKSKQMNINNLSNIPEVIDPGITIPIYEEEYENNGESNSQLQQQPQKLGSYRSRAGKFSNTLSNLLPSISAKLHHSKKNSHGKNGAEFSSSNNSSQSTVASKTPRASPSRSKMMESSIDGVTMDRPGSLTPPQDMEKLVHFPDSSNNFLIPAPRGSSDSFNLPHQISRTRNNTMSSQITSISSIAPKPRTSSGIWSSNASANDPMQQHLLQQLQPTTSNNTTNSNTLNDYSTKTAYFDNMVSTSGSQMADNKMNTNNLAIPNSVWSNTRQRSQSNASSIYTDAPLYEQPARASISSHYTIPTQESPLIADEIDPQSINWVTMDPTVPSINQISNLLPTNTISISNVFPLQHQQPQLNNAINLTSTSLATLCSKYGEVISARTLRNLNMALVEFSSVESAVKALDSLQGKEVSMIGAPSKISFAKILPMHQQPPQFLLNSQGLPLGLENNNLQPQPLLQEQLFNGAVTFQQQGNVSIPVFNQQSQQSQHQNHSSGSAGFSNVLHGYNNNNSMHGNNNNSANEKEQCPFPLPPPNVNEKEDLLREIIELFEANSDEYQINSLIKKSLNHKGTSDTQNFGPLPEPLSGREFDPPKLRELRKSIDSNAFSDLEIEQLAIAMLDELPELSSDYLGNTIVQKLFEHSSDIIKDIMLRKTSKYLTSMGVHKNGTWACQKMITMAHTPRQIMQVTQGVKDYCTPLINDQFGNYVIQCVLKFGFPWNQFIFESIIANFWVIVQNRYGARAVRACLEAHDIVTPEQSIVLSAMIVTYAEYLSTNSNGALLVTWFLDTSVLPNRHSILAPRLTKRIVELCGHRLASLTILKVLNYRGDDNARKIILDSLFGNVNAHDSSPPKELTKLLCETNYGPTFVHKVLAMPLLEDDLRAHIIKQVRKVLTDSTQIQPSRRLLEEVGLASPSSTHNKTKQQQQQHHNSSISHMFATPDTSGQHMRGLSVSSVKSGGSKHTTMNTTTTNGSSASTLSPGQPLNANSNSSMGYFSYPGVFPVSGFSGNASNGYAMNNDDLSSQFDMLNFNNGTRLSLPQLSLTNHNNTTMELVNNVGSSQPHTNNNNNNNNTNYNDDNTVFETLTLHSAN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
58AcetylationSYRSRAGKFSNTLSN
HHHHHHHHHHHHHHH
44.6324489116
62PhosphorylationRAGKFSNTLSNLLPS
HHHHHHHHHHHHHHH
30.3021440633
90PhosphorylationGKNGAEFSSSNNSSQ
CCCCCCCCCCCCCCC
25.1022369663
91PhosphorylationKNGAEFSSSNNSSQS
CCCCCCCCCCCCCCC
42.2622369663
92PhosphorylationNGAEFSSSNNSSQST
CCCCCCCCCCCCCCC
38.5422369663
95PhosphorylationEFSSSNNSSQSTVAS
CCCCCCCCCCCCCCC
33.7222369663
96PhosphorylationFSSSNNSSQSTVASK
CCCCCCCCCCCCCCC
30.2122369663
98PhosphorylationSSNNSSQSTVASKTP
CCCCCCCCCCCCCCC
27.1422369663
99PhosphorylationSNNSSQSTVASKTPR
CCCCCCCCCCCCCCC
16.6819795423
102PhosphorylationSSQSTVASKTPRASP
CCCCCCCCCCCCCCC
32.5022369663
104PhosphorylationQSTVASKTPRASPSR
CCCCCCCCCCCCCCH
18.6021440633
108PhosphorylationASKTPRASPSRSKMM
CCCCCCCCCCHHHHH
25.3721551504
110PhosphorylationKTPRASPSRSKMMES
CCCCCCCCHHHHHHH
46.8421440633
112PhosphorylationPRASPSRSKMMESSI
CCCCCCHHHHHHHCC
29.2824961812
117PhosphorylationSRSKMMESSIDGVTM
CHHHHHHHCCCCEEC
18.0722369663
118PhosphorylationRSKMMESSIDGVTMD
HHHHHHHCCCCEECC
16.0522369663
123PhosphorylationESSIDGVTMDRPGSL
HHCCCCEECCCCCCC
20.9122369663
129PhosphorylationVTMDRPGSLTPPQDM
EECCCCCCCCCCHHH
31.5822369663
131PhosphorylationMDRPGSLTPPQDMEK
CCCCCCCCCCHHHHH
34.3222369663
145PhosphorylationKLVHFPDSSNNFLIP
HHHCCCCCCCCEEEE
34.8922369663
146PhosphorylationLVHFPDSSNNFLIPA
HHCCCCCCCCEEEEC
43.0822369663
157PhosphorylationLIPAPRGSSDSFNLP
EEECCCCCCCCCCCC
32.0522369663
158PhosphorylationIPAPRGSSDSFNLPH
EECCCCCCCCCCCCH
39.8522369663
160PhosphorylationAPRGSSDSFNLPHQI
CCCCCCCCCCCCHHH
20.2722369663
168PhosphorylationFNLPHQISRTRNNTM
CCCCHHHHCCCCCCC
22.4922369663
174PhosphorylationISRTRNNTMSSQITS
HHCCCCCCCCCCEEE
23.2123749301
176PhosphorylationRTRNNTMSSQITSIS
CCCCCCCCCCEEEHH
19.6323749301
177PhosphorylationTRNNTMSSQITSISS
CCCCCCCCCEEEHHH
18.1225752575
180PhosphorylationNTMSSQITSISSIAP
CCCCCCEEEHHHCCC
16.6319779198
181PhosphorylationTMSSQITSISSIAPK
CCCCCEEEHHHCCCC
23.3125752575
183PhosphorylationSSQITSISSIAPKPR
CCCEEEHHHCCCCCC
18.5628152593
184PhosphorylationSQITSISSIAPKPRT
CCEEEHHHCCCCCCC
22.5423749301
192PhosphorylationIAPKPRTSSGIWSSN
CCCCCCCCCCCCCCC
28.0427738172
219PhosphorylationQQLQPTTSNNTTNSN
HHHCCCCCCCCCCCC
30.4727738172
244PhosphorylationYFDNMVSTSGSQMAD
HHCCCCCCCCHHHCC
26.2024961812
245PhosphorylationFDNMVSTSGSQMADN
HCCCCCCCCHHHCCC
29.0125752575
247PhosphorylationNMVSTSGSQMADNKM
CCCCCCCHHHCCCCC
19.2924961812
273PhosphorylationWSNTRQRSQSNASSI
HHCCCHHCHHCCCCC
29.6229136822
275PhosphorylationNTRQRSQSNASSIYT
CCCHHCHHCCCCCCC
35.2917330950
278PhosphorylationQRSQSNASSIYTDAP
HHCHHCCCCCCCCCC
22.8629136822
279PhosphorylationRSQSNASSIYTDAPL
HCHHCCCCCCCCCCC
19.7329136822
281PhosphorylationQSNASSIYTDAPLYE
HHCCCCCCCCCCCCC
10.6619779198
282PhosphorylationSNASSIYTDAPLYEQ
HCCCCCCCCCCCCCC
24.8229136822
413PhosphorylationSLQGKEVSMIGAPSK
HCCCCEEEECCCCCC
13.0330377154
419PhosphorylationVSMIGAPSKISFAKI
EEECCCCCCCCCHHH
41.9330377154
913PhosphorylationLEEVGLASPSSTHNK
HHHHCCCCCCCCCCH
30.2922369663
915PhosphorylationEVGLASPSSTHNKTK
HHCCCCCCCCCCHHH
45.4322369663
916PhosphorylationVGLASPSSTHNKTKQ
HCCCCCCCCCCHHHH
36.7522369663
917PhosphorylationGLASPSSTHNKTKQQ
CCCCCCCCCCHHHHH
33.5322369663
939PhosphorylationSISHMFATPDTSGQH
CHHHEECCCCCCCCC
15.4924961812
942PhosphorylationHMFATPDTSGQHMRG
HEECCCCCCCCCCCC
35.6424961812
943PhosphorylationMFATPDTSGQHMRGL
EECCCCCCCCCCCCE
43.7824961812
951PhosphorylationGQHMRGLSVSSVKSG
CCCCCCEEEEEEECC
23.8322369663
953PhosphorylationHMRGLSVSSVKSGGS
CCCCEEEEEEECCCC
26.4922369663
954PhosphorylationMRGLSVSSVKSGGSK
CCCEEEEEEECCCCC
31.2622369663
957PhosphorylationLSVSSVKSGGSKHTT
EEEEEEECCCCCCCE
46.3522369663
960PhosphorylationSSVKSGGSKHTTMNT
EEEECCCCCCCEEEC
25.4522369663

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of JSN1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of JSN1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of JSN1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ARPC3_YEASTARC18physical
16107558
SLX5_YEASTSLX5physical
11283351
RPN5_YEASTRPN5physical
11283351
SAC7_YEASTSAC7physical
11283351
VAC8_YEASTVAC8physical
11283351
CDC26_YEASTCDC26physical
11283351
VATO_YEASTVMA16physical
11283351
DID4_YEASTDID4physical
11283351
FEN1_YEASTRAD27physical
11283351
ORN_YEASTREX2physical
11283351
YL156_YEASTYLR156Wphysical
11283351
YL59W_YEASTYLR156Wphysical
11283351
YL161_YEASTYLR156Wphysical
11283351
PYRC_YEASTURA4physical
11283351
TAF11_YEASTTAF11physical
11283351
UBX4_YEASTUBX4physical
11283351
YN8S_YEASTYNR048Wphysical
11283351
2A5D_YEASTRTS1physical
11283351
TBCA_YEASTRBL2physical
11283351
LCF1_YEASTFAA1physical
11283351
PET20_YEASTPET20physical
11283351
MPT5_YEASTMPT5genetic
18094119
HXKA_YEASTHXK1physical
18094119
EIF3J_YEASTHCR1genetic
19061648
RPB1_YEASTRPO21genetic
19061648
IF5A2_YEASTANB1genetic
19061648
PFD5_YEASTGIM5genetic
19061648
TMA23_YEASTTMA23genetic
19061648
NOT4_YEASTMOT2genetic
19061648
LTV1_YEASTLTV1genetic
19061648
MLP1_YEASTMLP1genetic
19061648
PAP2_YEASTPAP2genetic
19061648
UAF30_YEASTUAF30genetic
19061648
DOA10_YEASTSSM4genetic
19061648
FAF1_YEASTFAF1genetic
19061648
CUS1_YEASTCUS1genetic
19061648
SAP30_YEASTSAP30genetic
19061648
JSN1_YEASTJSN1physical
19345193
RAD59_YEASTRAD59genetic
19547744
RV167_YEASTRVS167genetic
20526336
EAP1_YEASTEAP1physical
20705650
PMP2_YEASTPMP2physical
21685478
RV167_YEASTRVS167genetic
21987634
GABAT_YEASTUGA1genetic
21987634
CHO2_YEASTCHO2genetic
21987634
VPS1_YEASTVPS1genetic
21987634
ARPC3_YEASTARC18genetic
21987634
IRA2_YEASTIRA2genetic
21987634
YCY0_YEASTYCR090Cgenetic
27708008
VPS41_YEASTVPS41genetic
27708008
RPA14_YEASTRPA14genetic
27708008
UBC7_YEASTUBC7genetic
27708008
RE114_YEASTREC114genetic
27708008
PALA_YEASTRIM20genetic
27708008
TBP6_YEASTYTA6genetic
27708008
CDC24_YEASTCDC24genetic
27708008
TAF5_YEASTTAF5genetic
27708008
TRS20_YEASTTRS20genetic
27708008
RMRP_YEASTSNM1genetic
27708008
COG3_YEASTCOG3genetic
27708008
RPF2_YEASTRPF2genetic
27708008
SEC22_YEASTSEC22genetic
27708008
YAP6_YEASTYAP6genetic
27708008
RV167_YEASTRVS167genetic
27708008
YBP2_YEASTYBP2genetic
27708008
HUR1_YEASTHUR1genetic
27708008
SAP4_YEASTSAP4genetic
27708008
VMA21_YEASTVMA21genetic
27708008
SHU1_YEASTSHU1genetic
27708008
GIC1_YEASTGIC1genetic
27708008
LRP1_YEASTLRP1genetic
27708008
YIF5_YEASTYIL055Cgenetic
27708008
IRS4_YEASTIRS4genetic
27708008
DID2_YEASTDID2genetic
27708008
MMM1_YEASTMMM1genetic
27708008
ATG10_YEASTATG10genetic
27708008
CHA4_YEASTCHA4genetic
27708008
PIG1_YEASTPIG1genetic
27708008
COQ11_YEASTYLR290Cgenetic
27708008
LGUL_YEASTGLO1genetic
27708008
GAL80_YEASTGAL80genetic
27708008
PP2B2_YEASTCMP2genetic
27708008
MAC1_YEASTMAC1genetic
27708008
JLP2_YEASTJLP2genetic
27708008
YM71_YEASTYMR226Cgenetic
27708008
RTC1_YEASTRTC1genetic
27708008
WHI5_YEASTWHI5genetic
27708008
KIN4_YEASTKIN4genetic
27708008
SUR1_YEASTSUR1genetic
27708008
BEM3_YEASTBEM3genetic
27708008
TGS1_YEASTTGS1genetic
27708008
VPS4_YEASTVPS4genetic
27708008
ATG13_YEASTATG13genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of JSN1_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-129; THR-131; SER-157;SER-158; SER-160; SER-273; SER-913; SER-916; SER-951 AND SER-954, ANDMASS SPECTROMETRY.
"Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases.";
Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.;
Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-157 AND SER-913, ANDMASS SPECTROMETRY.

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