ERG8_YEAST - dbPTM
ERG8_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ERG8_YEAST
UniProt AC P24521
Protein Name Phosphomevalonate kinase
Gene Name ERG8
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 451
Subcellular Localization Cytoplasm.
Protein Description
Protein Sequence MSELRAFSAPGKALLAGGYLVLDTKYEAFVVGLSARMHAVAHPYGSLQGSDKFEVRVKSKQFKDGEWLYHISPKSGFIPVSIGGSKNPFIEKVIANVFSYFKPNMDDYCNRNLFVIDIFSDDAYHSQEDSVTEHRGNRRLSFHSHRIEEVPKTGLGSSAGLVTVLTTALASFFVSDLENNVDKYREVIHNLAQVAHCQAQGKIGSGFDVAAAAYGSIRYRRFPPALISNLPDIGSATYGSKLAHLVDEEDWNITIKSNHLPSGLTLWMGDIKNGSETVKLVQKVKNWYDSHMPESLKIYTELDHANSRFMDGLSKLDRLHETHDDYSDQIFESLERNDCTCQKYPEITEVRDAVATIRRSFRKITKESGADIEPPVQTSLLDDCQTLKGVLTCLIPGAGGYDAIAVITKQDVDLRAQTANDKRFSKVQWLDVTQADWGVRKEKDPETYLDK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
52AcetylationGSLQGSDKFEVRVKS
CCCCCCCCEEEEEEE		45.1624489116
368PhosphorylationFRKITKESGADIEPP
HHHHHHHCCCCCCCC		40.6229688323
378PhosphorylationDIEPPVQTSLLDDCQ
CCCCCCCCHHHHHHH		22.9029688323
379PhosphorylationIEPPVQTSLLDDCQT
CCCCCCCHHHHHHHH		15.1629688323
386PhosphorylationSLLDDCQTLKGVLTC
HHHHHHHHHHHHHHH		36.4529688323
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ERG8_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ERG8_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ERG8_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RL19A_YEASTRPL19Bgenetic
20093466
RL19B_YEASTRPL19Bgenetic
20093466
TPS1_YEASTTPS1genetic
20093466
CHK1_YEASTCHK1genetic
20093466
ATG9_YEASTATG9genetic
20093466
SLX5_YEASTSLX5genetic
20093466
DHAS_YEASTHOM2genetic
20093466
SAC3_YEASTSAC3genetic
20093466
YDR22_YEASTYDR222Wgenetic
20093466
XRN1_YEASTXRN1genetic
20093466
HUR1_YEASTHUR1genetic
20093466
PCP1_YEASTPCP1genetic
20093466
CCH1_YEASTCCH1genetic
20093466
SAY1_YEASTSAY1genetic
20093466
FSH1_YEASTFSH1genetic
20093466
VHR1_YEASTVHR1genetic
20093466
APQ12_YEASTAPQ12genetic
20093466
DHOM_YEASTHOM6genetic
20093466
SAC1_YEASTSAC1genetic
20093466
DCOR_YEASTSPE1genetic
20093466
FRMSR_YEASTYKL069Wgenetic
20093466
MDM35_YEASTMDM35genetic
20093466
VPS24_YEASTVPS24genetic
20093466
SRL3_YEASTSRL3genetic
20093466
RL8B_YEASTRPL8Bgenetic
20093466
SUB1_YEASTSUB1genetic
20093466
SDHF2_YEASTSDH5genetic
20093466
AIM39_YEASTAIM39genetic
20093466
YORA4_YEASTYOR114Wgenetic
20093466
FABD_YEASTMCT1genetic
20093466
SLY41_YEASTSLY41genetic
20093466
FUMH_YEASTFUM1genetic
20093466
MGR2_YEASTMGR2genetic
20093466
GGPPS_YEASTBTS1genetic
20093466
PMA2_YEASTPMA2genetic
20093466
CHL1_YEASTCHL1genetic
20093466
PRM7_YEASTPRM7genetic
20093466
FDFT_YEASTERG9genetic
21445244
HFA1_YEASTHFA1genetic
21445244
GGPPS_YEASTBTS1genetic
21623372
DCOR_YEASTSPE1genetic
21623372
AATC_YEASTAAT2genetic
21623372
CSG2_YEASTCSG2genetic
21623372
CBS_YEASTCYS4genetic
21623372
THDH_YEASTILV1genetic
21623372
PDX3_YEASTPDX3genetic
21623372
SUR1_YEASTSUR1genetic
21623372
DHOM_YEASTHOM6genetic
21623372
QCR2_YEASTQCR2genetic
21623372
PYRE_YEASTURA5genetic
21623372
CHK1_YEASTCHK1genetic
22282571
MCES_YEASTABD1genetic
27708008
SEC7_YEASTSEC7genetic
27708008
ERF3_YEASTSUP35genetic
27708008
CDC1_YEASTCDC1genetic
27708008
ACT_YEASTACT1genetic
27708008
CDC23_YEASTCDC23genetic
27708008
MCM1_YEASTMCM1genetic
27708008
PROF_YEASTPFY1genetic
27708008
SEC63_YEASTSEC63genetic
27708008
PSB5_YEASTPRE2genetic
27708008
SWI6_YEASTSWI6genetic
27708008
KPC1_YEASTPKC1genetic
27708008
MPS1_YEASTMPS1genetic
27708008
RIFK_YEASTFMN1genetic
27708008
GPI11_YEASTGPI11genetic
27708008
GPI8_YEASTGPI8genetic
27708008
GPI19_YEASTGPI19genetic
27708008
PRP3_YEASTPRP3genetic
27708008
PGTB1_YEASTCDC43genetic
27708008
MPPA_YEASTMAS2genetic
27708008
ATC7_YEASTNEO1genetic
27708008
CDC11_YEASTCDC11genetic
27708008
ORC3_YEASTORC3genetic
27708008
SED5_YEASTSED5genetic
27708008
MED14_YEASTRGR1genetic
27708008
BOS1_YEASTBOS1genetic
27708008
ERG27_YEASTERG27genetic
27708008
CFT2_YEASTCFT2genetic
27708008
SEC22_YEASTSEC22genetic
27708008
POB3_YEASTPOB3genetic
27708008
RNA14_YEASTRNA14genetic
27708008
RPAB3_YEASTRPB8genetic
27708008
CLP1_YEASTCLP1genetic
27708008
TBF1_YEASTTBF1genetic
27708008
PYC2_YEASTPYC2genetic
27708008
RS29B_YEASTRPS29Bgenetic
27708008
S2538_YEASTYDL119Cgenetic
27708008
VPS41_YEASTVPS41genetic
27708008
RRP8_YEASTRRP8genetic
27708008
PUF6_YEASTPUF6genetic
27708008
ECM32_YEASTECM32genetic
27708008
ATG1_YEASTATG1genetic
27708008
OPI1_YEASTOPI1genetic
27708008
HTD2_YEASTHTD2genetic
27708008
LPLA_YEASTAIM22genetic
27708008
MDM35_YEASTMDM35genetic
27708008
FABG_YEASTOAR1genetic
27708008
EF1G2_YEASTTEF4genetic
27708008
CTK1_YEASTCTK1genetic
27708008
ACE2_YEASTACE2genetic
27708008
ARV1_YEASTARV1genetic
27708008
RS29A_YEASTRPS29Agenetic
27708008
LIPA_YEASTLIP5genetic
27708008
GGPPS_YEASTBTS1genetic
27708008
RU2A_YEASTLEA1genetic
27708008
SRO7_YEASTSRO7genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ERG8_YEAST

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Related Literatures of Post-Translational Modification

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