UniProt ID | GRPE_YEAST | |
---|---|---|
UniProt AC | P38523 | |
Protein Name | GrpE protein homolog, mitochondrial | |
Gene Name | MGE1 | |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
Sequence Length | 228 | |
Subcellular Localization | Mitochondrion matrix . | |
Protein Description | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins and the association of SSC1 with TIM44.. | |
Protein Sequence | MRAFSAATVRATTRKSFIPMAPRTPFVTPSFTKNVGSMRRMRFYSDEAKSEESKENNEDLTEEQSEIKKLESQLSAKTKEASELKDRLLRSVADFRNLQQVTKKDIQKAKDFALQKFAKDLLESVDNFGHALNAFKEEDLQKSKEISDLYTGVRMTRDVFENTLRKHGIEKLDPLGEPFDPNKHEATFELPQPDKEPGTVFHVQQLGFTLNDRVIRPAKVGIVKGEEN | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
|
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
24 | Phosphorylation | FIPMAPRTPFVTPSF CCCCCCCCCCCCCHH | 21.73 | 19779198 | |
30 | Phosphorylation | RTPFVTPSFTKNVGS CCCCCCCHHHCCCCC | 35.86 | 19779198 | |
54 | Acetylation | EAKSEESKENNEDLT HHHCHHHHHCCCCCH | 68.68 | 24489116 | |
65 | Phosphorylation | EDLTEEQSEIKKLES CCCHHHHHHHHHHHH | 44.56 | 27017623 | |
68 | Acetylation | TEEQSEIKKLESQLS HHHHHHHHHHHHHHH | 47.45 | 24489116 | |
72 | Phosphorylation | SEIKKLESQLSAKTK HHHHHHHHHHHHHHH | 47.02 | 22369663 | |
75 | Phosphorylation | KKLESQLSAKTKEAS HHHHHHHHHHHHHHH | 21.78 | 22369663 | |
77 | 2-Hydroxyisobutyrylation | LESQLSAKTKEASEL HHHHHHHHHHHHHHH | 57.67 | - | |
79 | Acetylation | SQLSAKTKEASELKD HHHHHHHHHHHHHHH | 51.05 | 24489116 | |
85 | Succinylation | TKEASELKDRLLRSV HHHHHHHHHHHHHHH | 36.43 | 23954790 | |
85 | Acetylation | TKEASELKDRLLRSV HHHHHHHHHHHHHHH | 36.43 | 24489116 | |
102 | Phosphorylation | FRNLQQVTKKDIQKA HHCHHHHCHHHHHHH | 28.21 | 29734811 | |
103 | Acetylation | RNLQQVTKKDIQKAK HCHHHHCHHHHHHHH | 49.98 | 24489116 | |
103 | Succinylation | RNLQQVTKKDIQKAK HCHHHHCHHHHHHHH | 49.98 | 23954790 | |
110 | 2-Hydroxyisobutyrylation | KKDIQKAKDFALQKF HHHHHHHHHHHHHHH | 61.49 | - | |
116 | Acetylation | AKDFALQKFAKDLLE HHHHHHHHHHHHHHH | 48.41 | 24489116 | |
119 | Acetylation | FALQKFAKDLLESVD HHHHHHHHHHHHHHH | 52.63 | 25381059 | |
136 | Acetylation | GHALNAFKEEDLQKS HHHHHHHCHHHHHHC | 58.76 | 25381059 | |
144 | Acetylation | EEDLQKSKEISDLYT HHHHHHCHHHHHHHH | 67.13 | 24489116 | |
155 | Sulfoxidation | DLYTGVRMTRDVFEN HHHHHHHHHHHHHHH | 3.15 | 25428986 | |
171 | Acetylation | LRKHGIEKLDPLGEP HHHCCCCCCCCCCCC | 57.16 | 24489116 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GRPE_YEAST !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GRPE_YEAST !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GRPE_YEAST !! |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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