YET3_YEAST - dbPTM
YET3_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID YET3_YEAST
UniProt AC Q07451
Protein Name Endoplasmic reticulum transmembrane protein 3
Gene Name YET3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 203
Subcellular Localization Endoplasmic reticulum membrane
Multi-pass membrane protein .
Protein Description May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in invertase secretion..
Protein Sequence MSLYYTLVFAILVVEIFMFSILALPIPSRYRRPLTLLLLKPFKSSTVQVAIKCVLGFILLLFIDCINRVYSIDKELQLSSASQNNGAIIAQDRIEVLSRKFFAQRNMYLTGITLFLTFVVVRTFGLVIELLTMKDIYRASPPVASSDVKKNDSVTAEAAAQSGASKDDHGDEKNFELLKKIQDIDDEIARLKEKSESLQEEIN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
44PhosphorylationLLLKPFKSSTVQVAI
EEECCCCCCHHHHHH
31.4621126336
137PhosphorylationLLTMKDIYRASPPVA
HHCHHHHHHHCCCCC
15.4028152593
140PhosphorylationMKDIYRASPPVASSD
HHHHHHHCCCCCCCC
22.2728152593
145PhosphorylationRASPPVASSDVKKND
HHCCCCCCCCCCCCC
27.5724961812
146PhosphorylationASPPVASSDVKKNDS
HCCCCCCCCCCCCCC
36.3627214570
149UbiquitinationPVASSDVKKNDSVTA
CCCCCCCCCCCCHHH
51.3423749301
150UbiquitinationVASSDVKKNDSVTAE
CCCCCCCCCCCHHHH
66.8723749301
153PhosphorylationSDVKKNDSVTAEAAA
CCCCCCCCHHHHHHH
30.6628889911
155PhosphorylationVKKNDSVTAEAAAQS
CCCCCCHHHHHHHHH
23.8024961812
162PhosphorylationTAEAAAQSGASKDDH
HHHHHHHHCCCCCCC
31.4424961812
165PhosphorylationAAAQSGASKDDHGDE
HHHHHCCCCCCCCCH
39.8928889911
173AcetylationKDDHGDEKNFELLKK
CCCCCCHHHHHHHHH
72.2224489116
194UbiquitinationEIARLKEKSESLQEE
HHHHHHHHHHHHHHH
58.9223749301
195PhosphorylationIARLKEKSESLQEEI
HHHHHHHHHHHHHHH
33.2422369663
197PhosphorylationRLKEKSESLQEEIN-
HHHHHHHHHHHHHC-
42.3022369663

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of YET3_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of YET3_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of YET3_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SEC63_YEASTSEC63genetic
16269340
GOSR1_YEASTGOS1genetic
16269340
SCS2_YEASTSCS2genetic
16269340
ATC3_YEASTDRS2genetic
16269340
RIC1_YEASTRIC1genetic
16269340
DGK1_YEASTDGK1genetic
16269340
USA1_YEASTUSA1physical
18719252
YET1_YEASTYET1physical
20378542
SEC63_YEASTSEC63physical
20378542
SC61A_YEASTSEC61physical
20378542
SEC63_YEASTSEC63genetic
20378542
SEC66_YEASTSEC66genetic
19325107
SCS2_YEASTSCS2genetic
21372176
INO1_YEASTINO1genetic
21372176
YET3_YEASTYET3physical
22940862
HSP71_YEASTSSA1physical
22940862
SSB1_YEASTSSB1physical
22940862
RL2A_YEASTRPL2Aphysical
22940862
RL2B_YEASTRPL2Aphysical
22940862

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of YET3_YEAST

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Related Literatures of Post-Translational Modification

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