| UniProt ID | YET3_YEAST | |
|---|---|---|
| UniProt AC | Q07451 | |
| Protein Name | Endoplasmic reticulum transmembrane protein 3 | |
| Gene Name | YET3 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 203 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Multi-pass membrane protein . |
|
| Protein Description | May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in invertase secretion.. | |
| Protein Sequence | MSLYYTLVFAILVVEIFMFSILALPIPSRYRRPLTLLLLKPFKSSTVQVAIKCVLGFILLLFIDCINRVYSIDKELQLSSASQNNGAIIAQDRIEVLSRKFFAQRNMYLTGITLFLTFVVVRTFGLVIELLTMKDIYRASPPVASSDVKKNDSVTAEAAAQSGASKDDHGDEKNFELLKKIQDIDDEIARLKEKSESLQEEIN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 44 | Phosphorylation | LLLKPFKSSTVQVAI EEECCCCCCHHHHHH | 31.46 | 21126336 | |
| 137 | Phosphorylation | LLTMKDIYRASPPVA HHCHHHHHHHCCCCC | 15.40 | 28152593 | |
| 140 | Phosphorylation | MKDIYRASPPVASSD HHHHHHHCCCCCCCC | 22.27 | 28152593 | |
| 145 | Phosphorylation | RASPPVASSDVKKND HHCCCCCCCCCCCCC | 27.57 | 24961812 | |
| 146 | Phosphorylation | ASPPVASSDVKKNDS HCCCCCCCCCCCCCC | 36.36 | 27214570 | |
| 149 | Ubiquitination | PVASSDVKKNDSVTA CCCCCCCCCCCCHHH | 51.34 | 23749301 | |
| 150 | Ubiquitination | VASSDVKKNDSVTAE CCCCCCCCCCCHHHH | 66.87 | 23749301 | |
| 153 | Phosphorylation | SDVKKNDSVTAEAAA CCCCCCCCHHHHHHH | 30.66 | 28889911 | |
| 155 | Phosphorylation | VKKNDSVTAEAAAQS CCCCCCHHHHHHHHH | 23.80 | 24961812 | |
| 162 | Phosphorylation | TAEAAAQSGASKDDH HHHHHHHHCCCCCCC | 31.44 | 24961812 | |
| 165 | Phosphorylation | AAAQSGASKDDHGDE HHHHHCCCCCCCCCH | 39.89 | 28889911 | |
| 173 | Acetylation | KDDHGDEKNFELLKK CCCCCCHHHHHHHHH | 72.22 | 24489116 | |
| 194 | Ubiquitination | EIARLKEKSESLQEE HHHHHHHHHHHHHHH | 58.92 | 23749301 | |
| 195 | Phosphorylation | IARLKEKSESLQEEI HHHHHHHHHHHHHHH | 33.24 | 22369663 | |
| 197 | Phosphorylation | RLKEKSESLQEEIN- HHHHHHHHHHHHHC- | 42.30 | 22369663 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of YET3_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of YET3_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of YET3_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SEC63_YEAST | SEC63 | genetic | 16269340 | |
| GOSR1_YEAST | GOS1 | genetic | 16269340 | |
| SCS2_YEAST | SCS2 | genetic | 16269340 | |
| ATC3_YEAST | DRS2 | genetic | 16269340 | |
| RIC1_YEAST | RIC1 | genetic | 16269340 | |
| DGK1_YEAST | DGK1 | genetic | 16269340 | |
| USA1_YEAST | USA1 | physical | 18719252 | |
| YET1_YEAST | YET1 | physical | 20378542 | |
| SEC63_YEAST | SEC63 | physical | 20378542 | |
| SC61A_YEAST | SEC61 | physical | 20378542 | |
| SEC63_YEAST | SEC63 | genetic | 20378542 | |
| SEC66_YEAST | SEC66 | genetic | 19325107 | |
| SCS2_YEAST | SCS2 | genetic | 21372176 | |
| INO1_YEAST | INO1 | genetic | 21372176 | |
| YET3_YEAST | YET3 | physical | 22940862 | |
| HSP71_YEAST | SSA1 | physical | 22940862 | |
| SSB1_YEAST | SSB1 | physical | 22940862 | |
| RL2A_YEAST | RPL2A | physical | 22940862 | |
| RL2B_YEAST | RPL2A | physical | 22940862 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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