dbPTM

GTO1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GTO1_YEAST
UniProt AC	P48239
Protein Name	Glutathione S-transferase omega-like 1
Gene Name	GTO1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	356
Subcellular Localization	Peroxisome .
Protein Description	Active as '1-Cys' thiol transferase against beta-hydroxyethyl disulfide (HED), as dehydroascorbate reductase and as dimethylarsinic acid reductase, while not active against the standard GST substrate 1-chloro-2,4-dinitrobenzene (CDNB)..
Protein Sequence	MSVSYKGTISKTHSVFKPEKGRYYIYGALGCPFTHRAILARSLKKLEPVLGLVLSHWQLDSKGARFLPAPHRPEKYKERFFTATGGIASAKLDESEELGDVNNDSARLFVDGAFDPVENISRLSELYYLNDPKYPGTKFTVPVLWDSKTRKIVNNESGDIIRILNSGVFDEFIQSEETNVIDLVPHDLIDEIDKNIKWVHPKINLGVYKVGLAENGKIYETEVKTLFENLQKMECVLKENYKRLEEQFSGNKQKILAKYFVLGQRLTEADIRLYPSIIRFDVVYVQHFKCNLKTIRDGFPYLHLWLINLYWNYAEFRFTTDFNHIKLFYIRMEVSRNKINQFGIVPLGPKPDISRL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
8	Phosphorylation	MSVSYKGTISKTHSV CCCEEEEEEEECCEE	20.23	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GTO1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GTO1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GTO1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PWP2_YEAST	PWP2	physical	10688190
COA4_YEAST	COA4	genetic	27708008
FAL1_YEAST	FAL1	genetic	27708008
CDC37_YEAST	CDC37	genetic	27708008
SAD1_YEAST	SAD1	genetic	27708008
CDC23_YEAST	CDC23	genetic	27708008
MET30_YEAST	MET30	genetic	27708008
PRP19_YEAST	PRP19	genetic	27708008
ORC1_YEAST	ORC1	genetic	27708008
FUN30_YEAST	FUN30	genetic	27708008
YD061_YEAST	YDR061W	genetic	27708008
OCA6_YEAST	OCA6	genetic	27708008
ARX1_YEAST	ARX1	genetic	27708008
VBA4_YEAST	VBA4	genetic	27708008
ACL4_YEAST	YDR161W	genetic	27708008
BCS1_YEAST	BCS1	genetic	27708008
RLA4_YEAST	RPP2B	genetic	27708008
MON1_YEAST	MON1	genetic	27708008
RL8A_YEAST	RPL8A	genetic	27708008
SODM_YEAST	SOD2	genetic	27708008
SLT2_YEAST	SLT2	genetic	27708008
PIG2_YEAST	PIG2	genetic	27708008
FMC1_YEAST	FMC1	genetic	27708008
RCY1_YEAST	RCY1	genetic	27708008
BFA1_YEAST	BFA1	genetic	27708008
DHOM_YEAST	HOM6	genetic	27708008
ELM1_YEAST	ELM1	genetic	27708008
MDM35_YEAST	MDM35	genetic	27708008
FABG_YEAST	OAR1	genetic	27708008
UBI4P_YEAST	UBI4	genetic	27708008
ATG26_YEAST	ATG26	genetic	27708008
LIPB_YEAST	LIP2	genetic	27708008
YPT7_YEAST	YPT7	genetic	27708008
PET8_YEAST	PET8	genetic	27708008
PMS1_YEAST	PMS1	genetic	27708008
MKT1_YEAST	MKT1	genetic	27708008
CYB5_YEAST	CYB5	genetic	27708008
YNO0_YEAST	YNL140C	genetic	27708008
CY1_YEAST	CYT1	genetic	27708008
DIA2_YEAST	DIA2	genetic	27708008
LIPA_YEAST	LIP5	genetic	27708008
FABD_YEAST	MCT1	genetic	27708008
DGK1_YEAST	DGK1	genetic	27708008
PDE2_YEAST	PDE2	genetic	27708008
GGPPS_YEAST	BTS1	genetic	27708008
YP013_YEAST	CMR3	genetic	27708008
INO4_YEAST	INO4	genetic	27453043
CDC14_YEAST	CDC14	genetic	27453043
SWI6_YEAST	SWI6	genetic	27453043
INO2_YEAST	INO2	genetic	27453043
SSN3_YEAST	SSN3	genetic	27453043

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GTO1_YEAST

Related Literatures of Post-Translational Modification