FAL1_YEAST - dbPTM
FAL1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FAL1_YEAST
UniProt AC Q12099
Protein Name ATP-dependent RNA helicase FAL1
Gene Name FAL1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 399
Subcellular Localization Nucleus, nucleolus .
Protein Description ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA..
Protein Sequence MSFDREEDQKLKFKTSKKLKVSSTFESMNLKDDLLRGIYSYGFEAPSSIQSRAITQIISGKDVIAQAQSGTGKTATFTIGLLQAIDLRKKDLQALILSPTRELASQIGQVVKNLGDYMNVNAFAITGGKTLKDDLKKMQKHGCQAVSGTPGRVLDMIKKQMLQTRNVQMLVLDEADELLSETLGFKQQIYDIFAKLPKNCQVVVVSATMNKDILEVTRKFMNDPVKILVKRDEISLEGIKQYVVNVDKEEWKFDTLCDIYDSLTITQCVIFCNTKKKVDWLSQRLIQSNFAVVSMHGDMKQEERDKVMNDFRTGHSRVLISTDVWARGIDVQQVSLVINYDLPEIIENYIHRIGRSGRFGRKGVAINFITKADLAKLREIEKFYSIKINPMPANFAELS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSFDREEDQ
------CCCCHHHHH		35.5427717283
27PhosphorylationKVSSTFESMNLKDDL
CCCCCHHCCCCCHHH		14.5828889911
180PhosphorylationDEADELLSETLGFKQ
HHHHHHHHHHHCCHH		40.9521082442
182PhosphorylationADELLSETLGFKQQI
HHHHHHHHHCCHHHH		28.8928889911
255PhosphorylationKEEWKFDTLCDIYDS
HHHCCHHCHHHHHHH		32.2127017623
262PhosphorylationTLCDIYDSLTITQCV
CHHHHHHHCEEEEEE		15.5027017623
274PhosphorylationQCVIFCNTKKKVDWL
EEEEEECCHHHHHHH		45.4827017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FAL1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FAL1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FAL1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
BNI1_YEASTBNI1physical
11805826
APN2_YEASTAPN2genetic
20093466
MSH3_YEASTMSH3genetic
20093466
LIC4_YEASTATC1genetic
20093466
YG35_YEASTYGR125Wgenetic
20093466
HTD2_YEASTHTD2genetic
20093466
OSH3_YEASTOSH3genetic
20093466
ATG7_YEASTATG7genetic
20093466
YJ24_YEASTKCH1genetic
20093466
FABG_YEASTOAR1genetic
20093466
ATG10_YEASTATG10genetic
20093466
RSSA2_YEASTRPS0Bgenetic
20093466
ERG3_YEASTERG3genetic
20093466
LIPB_YEASTLIP2genetic
20093466
CHS5_YEASTCHS5genetic
20093466
YM24_YEASTYMR147Wgenetic
20093466
LIPA_YEASTLIP5genetic
20093466
COX10_YEASTCOX10genetic
20093466
AIM3_YEASTAIM3genetic
21035341
SGD1_YEASTSGD1genetic
21576267
SGD1_YEASTSGD1physical
21576267
PRS8_YEASTRPT6genetic
27708008
RPF1_YEASTRPF1genetic
27708008
SEN1_YEASTSEN1genetic
27708008
NOP2_YEASTNOP2genetic
27708008
MOT1_YEASTMOT1genetic
27708008
RXT2_YEASTRXT2genetic
27708008
SDS3_YEASTSDS3genetic
27708008
CDC27_YEASTCDC27genetic
27708008
KRR1_YEASTKRR1genetic
27708008
GPI8_YEASTGPI8genetic
27708008
FCF1_YEASTFCF1genetic
27708008
UTP5_YEASTUTP5genetic
27708008
GPI19_YEASTGPI19genetic
27708008
UTP6_YEASTUTP6genetic
27708008
RSP5_YEASTRSP5genetic
27708008
ESP1_YEASTESP1genetic
27708008
BCD1_YEASTBCD1genetic
27708008
RRP3_YEASTRRP3genetic
27708008
GPI16_YEASTGPI16genetic
27708008
UTP9_YEASTUTP9genetic
27708008
MET30_YEASTMET30genetic
27708008
NUP85_YEASTNUP85genetic
27708008
CDC11_YEASTCDC11genetic
27708008
MIF2_YEASTMIF2genetic
27708008
DCA13_YEASTSOF1genetic
27708008
NEP1_YEASTEMG1genetic
27708008
UTP13_YEASTUTP13genetic
27708008
DBP9_YEASTDBP9genetic
27708008
CDC91_YEASTGAB1genetic
27708008
UTP15_YEASTUTP15genetic
27708008
SPC24_YEASTSPC24genetic
27708008
RRP5_YEASTRRP5genetic
27708008
NAT10_YEASTKRE33genetic
27708008
IPL1_YEASTIPL1genetic
27708008
DIM1_YEASTDIM1genetic
27708008
SWC3_YEASTSWC3genetic
27708008
FUN30_YEASTFUN30genetic
27708008
PAT1_YEASTPAT1genetic
27708008
RT103_YEASTRTT103genetic
27708008
UBX5_YEASTUBX5genetic
27708008
KCC1_YEASTCMK1genetic
27708008
CGR1_YEASTCGR1genetic
27708008
MON1_YEASTMON1genetic
27708008
HTD2_YEASTHTD2genetic
27708008
THP2_YEASTTHP2genetic
27708008
LIPB_YEASTLIP2genetic
27708008
VPS71_YEASTVPS71genetic
27708008
DOM34_YEASTDOM34genetic
27708008
YNO0_YEASTYNL140Cgenetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FAL1_YEAST

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Related Literatures of Post-Translational Modification

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