MPC54_YEAST - dbPTM
MPC54_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MPC54_YEAST
UniProt AC Q08550
Protein Name Meiotic plaque component protein 54
Gene Name MPC54
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 464
Subcellular Localization Prospore membrane. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Cytoplasm, cytoskeleton, spindle pole. Localizes to the ends of spindle microtubules in cells in meiosis. Localizes to all four spindle pole bodies during m
Protein Description Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation..
Protein Sequence MPEDTSYSNSFEDYYNNSHAISPYKDSFYKEMTPSKPNVRFGDDDVNIFDQRKKVNEINKNNTVKRSIPSSISTTITPNKSSLKSPRGKRASKNSFDNETKLESKNETLKEVNDAVNRCYALCNIPTKHVSINSISDLAQTFETLAVGITHETNRKAECERSKNAIDSLYYHEQLEKKELNEKSLQMAIDHLLKVTKQNLRQADDGNKLKETEALKSFIEEIEEVDDNKISINSLQQQLLEEKTANNILRRDYYKLQERGRRLCHEFQELQDDYSKQMKQKEYEVQKLKNEIKVLLNMNDNLKAEKAHYSQKEKQYFQKYTYIEKYMNHVKEEYNRKEDECKKLNFIIDKSMKKIEHLERSLQTQFTAQNSFSTAMIQEEGPKDAHLKDRYHKVKEFMEQKLQTSKINDPSCSEAEALDNVLCLIESSMKTLDKNSKCYPIATKKCIKYVTDSPRLKENEHVTN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
33PhosphorylationDSFYKEMTPSKPNVR
CCCCCCCCCCCCCCC
26.0427017623
60AcetylationKKVNEINKNNTVKRS
HHHHHHCCCCCCCCC
58.1825381059
65AcetylationINKNNTVKRSIPSSI
HCCCCCCCCCCCCCC
38.0925381059
67PhosphorylationKNNTVKRSIPSSIST
CCCCCCCCCCCCCCC
32.8822890988
70PhosphorylationTVKRSIPSSISTTIT
CCCCCCCCCCCCEEC
38.3422890988
71PhosphorylationVKRSIPSSISTTITP
CCCCCCCCCCCEECC
18.4022890988
73PhosphorylationRSIPSSISTTITPNK
CCCCCCCCCEECCCH
22.8022890988
74PhosphorylationSIPSSISTTITPNKS
CCCCCCCCEECCCHH
22.1322890988
75PhosphorylationIPSSISTTITPNKSS
CCCCCCCEECCCHHH
18.9622890988
77PhosphorylationSSISTTITPNKSSLK
CCCCCEECCCHHHCC
20.7922890988
81PhosphorylationTTITPNKSSLKSPRG
CEECCCHHHCCCCCC
47.7622890988
82PhosphorylationTITPNKSSLKSPRGK
EECCCHHHCCCCCCC
41.2322890988
85PhosphorylationPNKSSLKSPRGKRAS
CCHHHCCCCCCCCCC
25.7322890988
196PhosphorylationIDHLLKVTKQNLRQA
HHHHHHHHHHHHHHC
25.8928889911
404PhosphorylationFMEQKLQTSKINDPS
HHHHHHCCCCCCCCC
42.2828889911
436PhosphorylationMKTLDKNSKCYPIAT
HCCCCCCCCEEECCH
29.8228889911
453PhosphorylationCIKYVTDSPRLKENE
HHHHHCCCCCHHCCC
11.5327214570

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MPC54_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MPC54_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MPC54_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ADY3_YEASTADY3physical
11742972
MPC54_YEASTMPC54physical
10899120
MPC70_YEASTSPO21physical
10899120
NUD1_YEASTNUD1physical
10899120
SPC24_YEASTSPC24physical
10899120
CNM67_YEASTCNM67physical
20826607
MPC70_YEASTSPO21physical
20826607
MPC54_YEASTMPC54physical
20826607
MEI5_YEASTMEI5physical
22875988
YO304_YEASTBIL1physical
22875988
YAJ9_YEASTYAR029Wgenetic
27708008
YCZ2_YEASTYCR102Cgenetic
27708008
MTU1_YEASTSLM3genetic
27708008
GGA1_YEASTGGA1genetic
27708008
RS3A2_YEASTRPS1Bgenetic
27708008
MET8_YEASTMET8genetic
27708008
MNN10_YEASTMNN10genetic
27708008
YFAS1_YEASTYDR262Wgenetic
27708008
RS26B_YEASTRPS26Bgenetic
27708008
GET1_YEASTGET1genetic
27708008
QCR9_YEASTQCR9genetic
27708008
SODM_YEASTSOD2genetic
27708008
DAL81_YEASTDAL81genetic
27708008
YJ24_YEASTKCH1genetic
27708008
CBF1_YEASTCBF1genetic
27708008
NDK_YEASTYNK1genetic
27708008
DBR1_YEASTDBR1genetic
27708008
COX12_YEASTCOX12genetic
27708008
HAP5_YEASTHAP5genetic
27708008
SPP1_YEASTSPP1genetic
27708008
QCR2_YEASTQCR2genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MPC54_YEAST

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Related Literatures of Post-Translational Modification

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