GGA1_YEAST - dbPTM
GGA1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GGA1_YEAST
UniProt AC Q06336
Protein Name ADP-ribosylation factor-binding protein GGA1
Gene Name GGA1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 557
Subcellular Localization Golgi apparatus, trans-Golgi network.
Protein Description May play a role in the regulation of membrane traffic through the trans-Golgi network..
Protein Sequence MPQRIELTSEPVRKPRSTESSLLRKIQRACRSTLPEPDLGLNLDVADYINSKQGATPREAVLAIEKLVNNGDTQAAVFALSLLDVLVKNCGYSIHLQISRKEFLNDLVKRFPEQPPLRYSKVQQMILEAIEEWYQTICKHASYKDDLQYINDMHKLLKYKGYTFPKVGSENLAVLRPNDQLRTPSELQEEQERAQAAKLEELLRSGKPDDLKEANKLMKIMAGFKDDTKVAVKQAINNELNKLKRKADLFNEMLTSADEPDLENEAIQELYGDLKSAQPKFKKLIEEERDDDALVSNLSKFNDLVIQLLKRYKSIKGMKEEELNVPDTNEPAKELNLIDFDDDTTANTPSVTSPSKSLQPFDDLLGDFNKVSLSSPKSPQENDTVVDILGDAHSKSSGIDLLDFDSQPGESKTALSAYSNSIVLPNGLLNSSSNSKEITAQSQRHILNQSDHLRIDYELTRESMTKLRLVIFYSNISSDPITNFALLVASPKGTTLSLQPQSGNMLQSNSRDGIKQIASVEGISVNLGKPIKLKWKANYCTKGDSKEESGTTSLPTI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
183PhosphorylationRPNDQLRTPSELQEE
CCCCCCCCHHHHHHH		39.5021126336
185PhosphorylationNDQLRTPSELQEEQE
CCCCCCHHHHHHHHH		50.7725752575
225UbiquitinationMKIMAGFKDDTKVAV
HHHHCCCCCCHHHHH		54.5023749301
242UbiquitinationAINNELNKLKRKADL
HHHHHHHHHHHHHHH		68.9323749301
246UbiquitinationELNKLKRKADLFNEM
HHHHHHHHHHHHHHH		44.6724961812
310AcetylationDLVIQLLKRYKSIKG
HHHHHHHHHHHHCCC		63.3724489116
344PhosphorylationLIDFDDDTTANTPSV
CEECCCCCCCCCCCC		34.5022369663
345PhosphorylationIDFDDDTTANTPSVT
EECCCCCCCCCCCCC		25.5522369663
348PhosphorylationDDDTTANTPSVTSPS
CCCCCCCCCCCCCCC		17.9322369663
350PhosphorylationDTTANTPSVTSPSKS
CCCCCCCCCCCCCCC		35.6722369663
352PhosphorylationTANTPSVTSPSKSLQ
CCCCCCCCCCCCCCC		38.9825521595
353PhosphorylationANTPSVTSPSKSLQP
CCCCCCCCCCCCCCC		25.6422369663
355PhosphorylationTPSVTSPSKSLQPFD
CCCCCCCCCCCCCHH		34.3420377248
357PhosphorylationSVTSPSKSLQPFDDL
CCCCCCCCCCCHHHH		36.2522369663
372PhosphorylationLGDFNKVSLSSPKSP
HCCCCCCCCCCCCCC		24.9222369663
374PhosphorylationDFNKVSLSSPKSPQE
CCCCCCCCCCCCCCC		36.7725521595
375PhosphorylationFNKVSLSSPKSPQEN
CCCCCCCCCCCCCCC		41.4625521595
378PhosphorylationVSLSSPKSPQENDTV
CCCCCCCCCCCCCCE		34.8922369663
384PhosphorylationKSPQENDTVVDILGD
CCCCCCCCEEEHHCC		33.7322369663
394PhosphorylationDILGDAHSKSSGIDL
EHHCCCCCCCCCCCE		35.6322369663
396PhosphorylationLGDAHSKSSGIDLLD
HCCCCCCCCCCCEEE		36.4922369663
397PhosphorylationGDAHSKSSGIDLLDF
CCCCCCCCCCCEEEC		43.4322369663
406PhosphorylationIDLLDFDSQPGESKT
CCEEECCCCCCCCHH		37.9629136822
411PhosphorylationFDSQPGESKTALSAY
CCCCCCCCHHHHHHH		41.0222369663
413PhosphorylationSQPGESKTALSAYSN
CCCCCCHHHHHHHCC		41.9530377154
416PhosphorylationGESKTALSAYSNSIV
CCCHHHHHHHCCCEE		23.7730377154
431PhosphorylationLPNGLLNSSSNSKEI
CCCCCCCCCCCCCCC		34.8030377154
432PhosphorylationPNGLLNSSSNSKEIT
CCCCCCCCCCCCCCH		32.2530377154
435PhosphorylationLLNSSSNSKEITAQS
CCCCCCCCCCCHHHH		33.3530377154
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GGA1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GGA1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GGA1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CLH_YEASTCHC1physical
11408593
CLH_YEASTCHC1physical
11689690
ARF1_YEASTARF1physical
11124697
ARF2_YEASTARF2physical
11124697
GGA2_YEASTGGA2genetic
11689690
CLH_YEASTCHC1genetic
11408593
GGA2_YEASTGGA2genetic
11408593
GGA2_YEASTGGA2genetic
10747089
GGA2_YEASTGGA2genetic
17895371
YPT6_YEASTYPT6genetic
19398763
GGA2_YEASTGGA2genetic
19398763
RL19A_YEASTRPL19Bgenetic
20093466
RL19B_YEASTRPL19Bgenetic
20093466
MBA1_YEASTMBA1genetic
20093466
UME6_YEASTUME6genetic
20093466
MED5_YEASTNUT1genetic
20093466
PDK2_YEASTPKP2genetic
20093466
G3P3_YEASTTDH3genetic
20093466
GGA2_YEASTGGA2genetic
20093466
FPS1_YEASTFPS1genetic
20093466
PFD6_YEASTYKE2genetic
20093466
FRE1_YEASTFRE1genetic
20093466
YPT6_YEASTYPT6genetic
20093466
ROM2_YEASTROM2genetic
20093466
SOK2_YEASTSOK2genetic
20093466
SSO2_YEASTSSO2genetic
20093466
CIK1_YEASTCIK1genetic
20093466
SCS7_YEASTSCS7genetic
20093466
NST1_YEASTNST1genetic
20093466
WHI2_YEASTWHI2genetic
20093466
RS10A_YEASTRPS10Agenetic
20093466
LDB19_YEASTLDB19genetic
20093466
KPYK2_YEASTPYK2genetic
20093466
DBP1_YEASTDBP1genetic
20093466
ELP4_YEASTELP4genetic
20093466
RL21B_YEASTRPL21Bgenetic
20093466
YP066_YEASTRGL1genetic
20093466
ARL3_YEASTARL3genetic
20093466
ULA1_YEASTULA1genetic
20093466
SULX_YEASTYPR003Cgenetic
20093466
CSR2_YEASTCSR2genetic
20093466
CHMU_YEASTARO7genetic
20093466
YPR09_YEASTYPR109Wgenetic
20093466
KAR3_YEASTKAR3genetic
20093466
RV161_YEASTRVS161genetic
20526336
RV167_YEASTRVS167genetic
20526336
GGA2_YEASTGGA2genetic
20526336
PER1_YEASTPER1genetic
20526336
SRO77_YEASTSRO77genetic
20526336
KEX2_YEASTKEX2physical
23408788
MON2_YEASTMON2physical
18418388
GGA2_YEASTGGA2genetic
10747088
GGA2_YEASTGGA2genetic
11124697
UBC_HUMANUBCphysical
17494868
PDK2_YEASTPKP2genetic
27708008
CSR2_YEASTCSR2genetic
27708008
RL19A_YEASTRPL19Bgenetic
27708008
RL19B_YEASTRPL19Bgenetic
27708008
EF1A_YEASTTEF2genetic
27708008
AGP2_YEASTAGP2genetic
27708008
MBA1_YEASTMBA1genetic
27708008
RIM15_YEASTRIM15genetic
27708008
MED5_YEASTNUT1genetic
27708008
MED20_YEASTSRB2genetic
27708008
ICE2_YEASTICE2genetic
27708008
DAL81_YEASTDAL81genetic
27708008
VPS53_YEASTVPS53genetic
27708008
FPS1_YEASTFPS1genetic
27708008
UPS1_YEASTUPS1genetic
27708008
YPT6_YEASTYPT6genetic
27708008
ROM2_YEASTROM2genetic
27708008
MSC1_YEASTMSC1genetic
27708008
SOK2_YEASTSOK2genetic
27708008
SSO2_YEASTSSO2genetic
27708008
CYB5_YEASTCYB5genetic
27708008
TLG2_YEASTTLG2genetic
27708008
BUB3_YEASTBUB3genetic
27708008
MKK1_YEASTMKK1genetic
27708008
PALA_YEASTRIM20genetic
27708008
LDB19_YEASTLDB19genetic
27708008
ARL3_YEASTARL3genetic
27708008
YP066_YEASTRGL1genetic
27708008
ELP4_YEASTELP4genetic
27708008
DBP1_YEASTDBP1genetic
27708008
YAR1_YEASTYAR1genetic
27708008
MDL2_YEASTMDL2genetic
27708008
EAF3_YEASTEAF3genetic
27708008
YP098_YEASTYPR098Cgenetic
27708008
KAR3_YEASTKAR3genetic
27708008
GGA2_YEASTGGA2genetic
26786099
SLT2_YEASTSLT2genetic
26786099
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GGA1_YEAST

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-185; SER-350; SER-355;SER-372; SER-374; SER-375; SER-378; THR-384; SER-394; SER-396 ANDSER-397, AND MASS SPECTROMETRY.
"Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases.";
Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.;
Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-375 AND SER-378, ANDMASS SPECTROMETRY.
"Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae.";
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.;
J. Proteome Res. 6:1190-1197(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-348; SER-357 ANDSER-378, AND MASS SPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory