SULX_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SULX_YEAST
• UniProt AC: P53394
• Protein Name: Putative sulfate transporter YPR003C
• Gene Name: YPR003C
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 754
• Subcellular Localization: Endoplasmic reticulum membrane ; Multi-pass membrane protein .
• Protein Description: Possible sulfate transporter..
• Protein Sequence: MTSNNSLLGRGRMSYSSTAPPRFKRSVDQRDTFSDNFDYDKDSSNRGRTYIAASNSTTGVPPPNNSRSGCTNNTNNTNNTSNTSNTNNNDSVDENTVFETLPYYLPCFSWLPEYTFNKLWGDVIAGISVASFQIPLALSYTTSIAHVPPLCGLYSLAISPFVYGILGSVPQMIVGPESAISLVVGQAVESITLHKENVSLIDISTVITFVSGTILLFSGISRFGFLGNVLSKALLRGFISSVGLVMIINSLISELKLDKFLVSLPQHYHTPFEKILFLIDYAPAQYHIPTAIFSGCCLIVLFLTRLLKRKLMKYHKSAIFFPDILLVVIVTILISMKFNLKHRYGISIIGDFSMDNFDELKNPLTRPRRKLIPDLFSASLIVAMLGFFESTTASKSLGTTYNLTVSSNRELVALGFMNIVISLFGALPAFGGYGRSKINALSGAQSVMSGVFMGVITLITMNLLLQFVHYIPNCVLSVITTIIGISLLEEVPGDIKFHLRCGGFSELFVFAVTFCTTIFYSIEAGICIGCVYSIINIIKHSAKSRIQILARVAGTSNFTNLDDYMMNMKRNSLDVEGTEEIEGCMIVRIPEPLTFTNSEDLKQRLDRIERYGSSKIHPGRKSLRSKDSIKYVIFDLGGMTSIDSSAAQVLEEIITSYKRRNVFIYLVNVSINDKVRRRLFKAGVAASVERAQANNNENNTSNTFSDAGETYSPYFDSIDAALYEIEKMKIKGNNVPNNDSESFMSNTLFNSSLV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MTSNNSLLGRGRM --CCCCCCCCCCCCC	29.26	28152593
14	Phosphorylation	LLGRGRMSYSSTAPP CCCCCCCCCCCCCCC	22.09	23749301
34	Phosphorylation	VDQRDTFSDNFDYDK CCCCCCCCCCCCCCC	33.46	28889911
41	Ubiquitination	SDNFDYDKDSSNRGR CCCCCCCCCCCCCCC	53.96	23749301
49	Phosphorylation	DSSNRGRTYIAASNS CCCCCCCEEEEECCC	23.31	27017623
50	Phosphorylation	SSNRGRTYIAASNST CCCCCCEEEEECCCC	6.29	27017623
54	Phosphorylation	GRTYIAASNSTTGVP CCEEEEECCCCCCCC	23.45	27017623
56	Phosphorylation	TYIAASNSTTGVPPP EEEEECCCCCCCCCC	25.50	27017623
57	Phosphorylation	YIAASNSTTGVPPPN EEEECCCCCCCCCCC	31.64	27017623
58	Phosphorylation	IAASNSTTGVPPPNN EEECCCCCCCCCCCC	35.68	27017623
66	Phosphorylation	GVPPPNNSRSGCTNN CCCCCCCCCCCCCCC	34.17	27017623
231	Phosphorylation	GFLGNVLSKALLRGF HHHHHHHHHHHHHHH	16.17	15665377
740	Phosphorylation	NNVPNNDSESFMSNT CCCCCCCCHHHHHCC	36.94	21440633
742	Phosphorylation	VPNNDSESFMSNTLF CCCCCCHHHHHCCCC	30.15	20377248
745	Phosphorylation	NDSESFMSNTLFNSS CCCHHHHHCCCCCCC	25.34	20377248
747	Phosphorylation	SESFMSNTLFNSSLV CHHHHHCCCCCCCCC	25.97	21440633

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SULX_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SULX_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SULX_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YOP1_YEAST	YOP1	genetic	16269340
GSF2_YEAST	GSF2	genetic	16269340
PMA1_YEAST	PMA1	genetic	16269340
RIC1_YEAST	RIC1	genetic	16269340
RGP1_YEAST	RGP1	genetic	16269340
MKAR_YEAST	IFA38	physical	16093310
DAL5_YEAST	DAL5	physical	16093310
SULX_YEAST	YPR003C	physical	16093310
CDC11_YEAST	CDC11	genetic	27708008
ARPC1_YEAST	ARC40	genetic	27708008
RPB1_YEAST	RPO21	genetic	27708008
NOP14_YEAST	NOP14	genetic	27708008
TSC11_YEAST	TSC11	genetic	27708008
MOB2_YEAST	MOB2	genetic	27708008
CWC16_YEAST	YJU2	genetic	27708008
GFA1_YEAST	GFA1	genetic	27708008
CDC42_YEAST	CDC42	genetic	27708008
PRP24_YEAST	PRP24	genetic	27708008
RPC6_YEAST	RPC34	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.