AGP2_YEAST - dbPTM
AGP2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID AGP2_YEAST
UniProt AC P38090
Protein Name General amino acid permease AGP2
Gene Name AGP2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 596
Subcellular Localization Membrane
Multi-pass membrane protein.
Protein Description General amino acid permease with broad substrate specificity. Can also transport carnitine..
Protein Sequence MTKERMTIDYENDGDFEYDKNKYKTITTRIKSIEPSEGWLEPSGSVGHINTIPEAGDVHVDEHEDRGSSIDDDSRTYLLYFTETRRKLENRHVQLIAISGVIGTALFVAIGKALYRGGPASLLLAFALWCVPILCITVSTAEMVCFFPVSSPFLRLATKCVDDSLAVMASWNFWFLECVQIPFEIVSVNTIIHYWRDDYSAGIPLAVQVVLYLLISICAVKYYGEMEFWLASFKIILALGLFTFTFITMLGGNPEHDRYGFRNYGESPFKKYFPDGNDVGKSSGYFQGFLACLIQASFTIAGGEYISMLAGEVKRPRKVLPKAFKQVFVRLTFLFLGSCLCVGIVCSPNDPDLTAAINEARPGAGSSPYVIAMNNLKIRILPDIVNIALITAAFSAGNAYTYCSSRTFYGMALDGYAPKIFTRCNRHGVPIYSVAISLVWALVSLLQLNSNSAVVLNWLINLITASQLINFVVLCIVYLFFRRAYHVQQDSLPKLPFRSWGQPYTAIIGLVSCSAMILIQGYTVFFPKLWNTQDFLFSYLMVFINIGIYVGYKFIWKRGKDHFKNPHEIDFSKELTEIENHEIESSFEKFQYYSKA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
20UbiquitinationDGDFEYDKNKYKTIT
CCCCCCCCCCEEEEE
55.2123749301
22UbiquitinationDFEYDKNKYKTITTR
CCCCCCCCEEEEEEE
54.5924961812
24UbiquitinationEYDKNKYKTITTRIK
CCCCCCEEEEEEEEE
34.7523749301
45PhosphorylationGWLEPSGSVGHINTI
CCCCCCCCCCEEEEC
29.3019779198
68PhosphorylationDEHEDRGSSIDDDSR
CCCCCCCCCCCCCCC
25.6419779198
69PhosphorylationEHEDRGSSIDDDSRT
CCCCCCCCCCCCCCE
32.6227214570
74PhosphorylationGSSIDDDSRTYLLYF
CCCCCCCCCEEEEEE
33.2528889911
76PhosphorylationSIDDDSRTYLLYFTE
CCCCCCCEEEEEEHH
23.6019779198
77PhosphorylationIDDDSRTYLLYFTET
CCCCCCEEEEEEHHH
8.1319779198
80PhosphorylationDSRTYLLYFTETRRK
CCCEEEEEEHHHHHH
13.0819779198
82PhosphorylationRTYLLYFTETRRKLE
CEEEEEEHHHHHHHC
23.9219779198
586PhosphorylationENHEIESSFEKFQYY
HCCCHHHHHHHHHHH
25.3225371407
595UbiquitinationEKFQYYSKA------
HHHHHHCCC------
41.8323749301

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of AGP2_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of AGP2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of AGP2_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ATC2_YEASTPMC1physical
18467557
MRM2_YEASTMRM2genetic
27708008
GSP2_YEASTGSP2genetic
27708008
MRH1_YEASTMRH1genetic
27708008
CAJ1_YEASTCAJ1genetic
27708008
SHC1_YEASTSHC1genetic
27708008
DCOR_YEASTSPE1genetic
27708008
MKS1_YEASTMKS1genetic
27708008
CPT1_YEASTCPT1genetic
27708008
INO4_YEASTINO4genetic
27708008
YO131_YEASTYOL131Wgenetic
27708008
DIA2_YEASTDIA2genetic
27708008
SYC1_YEASTSYC1genetic
27708008
RS10A_YEASTRPS10Agenetic
27708008
ATG21_YEASTATG21genetic
27708008
AP1G1_YEASTAPL4genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of AGP2_YEAST

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Related Literatures of Post-Translational Modification

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