| UniProt ID | GGA2_YEAST | |
|---|---|---|
| UniProt AC | P38817 | |
| Protein Name | ADP-ribosylation factor-binding protein GGA2 | |
| Gene Name | GGA2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 585 | |
| Subcellular Localization | Golgi apparatus, trans-Golgi network. | |
| Protein Description | May play a role in the regulation of membrane traffic through the trans-Golgi network.. | |
| Protein Sequence | MSHPHSHSIYLSELPVRKPQALGNPLLRKIQRACRMSLAEPDLALNLDIADYINEKQGAAPRDAAIALAKLINNRESHVAIFALSLLDVLVKNCGYPFHLQISRKEFLNELVKRFPGHPPLRYSKIQRLILTAIEEWYQTICKHSSYKNDMGYIRDMHRLLKYKGYAFPKISESDLAVLKPSNQLKTASEIQKEQEIAQAAKLEELIRRGKPEDLREANKLMKIMAGFKEDNAVQAKQAISSELNKLKRKADLLNEMLESPDSQNWDNETTQELHSALKVAQPKFQKIIEEEQEDDALVQDLLKFNDTVNQLLEKFNLLKNGDSNAASQIHPSHVSAPLQQSSGALTNEINLIDFNDLDEAPSQGNNNTNGTGTPAAAETSVNDLLGDLTDLSISNPSTANQASFGLGGDIVLGSSQPAPPVTTTNNSNNTLDLLGLSTPQSPTNSQAVNSSGFDLLMGFNPTTGTTTAPARTLVNQSPNLKIEFEISRESNSVIRIKSFFTNLSSSPISNLVFLLAVPKSMSLKLQPQSSNFMIGNAKDGISQEGTIENAPANPSKALKVKWKVNYSVNSTQAEETAVFTLPNV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSHPHSHSI ------CCCCCCCCE | 45.81 | 28889911 | |
| 6 | Phosphorylation | --MSHPHSHSIYLSE --CCCCCCCCEEECC | 24.31 | 24961812 | |
| 8 | Phosphorylation | MSHPHSHSIYLSELP CCCCCCCCEEECCCC | 18.88 | 28889911 | |
| 10 | Phosphorylation | HPHSHSIYLSELPVR CCCCCCEEECCCCCC | 13.74 | 28132839 | |
| 18 | Ubiquitination | LSELPVRKPQALGNP ECCCCCCCCHHHCCH | 41.54 | 23749301 | |
| 37 | Phosphorylation | IQRACRMSLAEPDLA HHHHHHCCCCCCCHH | 12.69 | 21440633 | |
| 70 | Acetylation | DAAIALAKLINNRES HHHHHHHHHHCCCCH | 51.23 | 24489116 | |
| 113 | Acetylation | EFLNELVKRFPGHPP HHHHHHHHHCCCCCC | 62.03 | 24489116 | |
| 148 | Acetylation | ICKHSSYKNDMGYIR HHHCCCCCCCHHHHH | 48.71 | 22865919 | |
| 153 | Phosphorylation | SYKNDMGYIRDMHRL CCCCCHHHHHHHHHH | 6.02 | 28889911 | |
| 170 | Acetylation | YKGYAFPKISESDLA HCCCCCCCCCHHHHE | 53.03 | 24489116 | |
| 180 | Acetylation | ESDLAVLKPSNQLKT HHHHEEECCCHHCCC | 39.54 | 24489116 | |
| 180 | Ubiquitination | ESDLAVLKPSNQLKT HHHHEEECCCHHCCC | 39.54 | 23749301 | |
| 182 | Phosphorylation | DLAVLKPSNQLKTAS HHEEECCCHHCCCHH | 35.30 | 21440633 | |
| 193 | Acetylation | KTASEIQKEQEIAQA CCHHHHHHHHHHHHH | 68.01 | 24489116 | |
| 193 | Ubiquitination | KTASEIQKEQEIAQA CCHHHHHHHHHHHHH | 68.01 | 23749301 | |
| 202 | Acetylation | QEIAQAAKLEELIRR HHHHHHHHHHHHHHC | 60.49 | 24489116 | |
| 229 | Acetylation | MKIMAGFKEDNAVQA HHHHHCCCCCCHHHH | 64.34 | 24489116 | |
| 229 | Ubiquitination | MKIMAGFKEDNAVQA HHHHHCCCCCCHHHH | 64.34 | 23749301 | |
| 237 | Ubiquitination | EDNAVQAKQAISSEL CCCHHHHHHHHHHHH | 24.15 | 23749301 | |
| 246 | Acetylation | AISSELNKLKRKADL HHHHHHHHHHHHHHH | 68.93 | 24489116 | |
| 246 | Ubiquitination | AISSELNKLKRKADL HHHHHHHHHHHHHHH | 68.93 | 23749301 | |
| 248 | Ubiquitination | SSELNKLKRKADLLN HHHHHHHHHHHHHHH | 54.16 | 22817900 | |
| 250 | Ubiquitination | ELNKLKRKADLLNEM HHHHHHHHHHHHHHH | 44.67 | 24961812 | |
| 279 | Ubiquitination | QELHSALKVAQPKFQ HHHHHHHHHHCHHHH | 34.93 | 24961812 | |
| 284 | Ubiquitination | ALKVAQPKFQKIIEE HHHHHCHHHHHHHHH | 48.63 | 22817900 | |
| 287 | Ubiquitination | VAQPKFQKIIEEEQE HHCHHHHHHHHHHHC | 49.11 | 23749301 | |
| 539 | Ubiquitination | NFMIGNAKDGISQEG CEEEEECCCCCCCCC | 61.56 | 17644757 | |
| 557 | Ubiquitination | NAPANPSKALKVKWK CCCCCHHHCEEEEEE | 60.02 | 17644757 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GGA2_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GGA2_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GGA2_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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