| UniProt ID | IRC21_YEAST | |
|---|---|---|
| UniProt AC | Q04772 | |
| Protein Name | Increased recombination centers protein 21 | |
| Gene Name | IRC21 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 201 | |
| Subcellular Localization | ||
| Protein Description | Involved in resistance to carboplatin and cisplatin. Is probably involved in a pathway contributing to genomic integrity.. | |
| Protein Sequence | MSSDGMNRDVSNSKPNVRFAAPQRLSVAHPAISSPLHMPMSKSSRKPLVRTKIRLDPGHSALDWHSLTSNPANYYTKFVSLQLIQDLLDDPVFQKDNFKFSPSQLKNQLLVQKIPLYKIMPPLRINRKIVKKHCKGEDELWCVINGKVYDISSYLKFHPGGTDILIKHRNSDDLITYFNKYHQWVNYEKLLQVCFIGVVCE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 34 | Phosphorylation | VAHPAISSPLHMPMS CCCCCCCCCCCCCCC | 25.93 | 28889911 | |
| 99 | Acetylation | VFQKDNFKFSPSQLK CCCCCCCCCCHHHHH | 51.71 | 24489116 | |
| 118 | Ubiquitination | VQKIPLYKIMPPLRI EEECCHHHCCCCCCC | 39.96 | 24961812 | |
| 167 | Acetylation | GGTDILIKHRNSDDL CCCEEEEEECCHHHH | 32.82 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of IRC21_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of IRC21_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of IRC21_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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