| UniProt ID | THI72_YEAST | |
|---|---|---|
| UniProt AC | Q08579 | |
| Protein Name | Thiamine transporter THI72 | |
| Gene Name | THI72 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 599 | |
| Subcellular Localization |
Membrane Multi-pass membrane protein. |
|
| Protein Description | Low affinity thiamine transporter responsible for intake of thiamine. It is possible that the primary function is the uptake of closely related compounds and that thiamine transport is a secondary activity of these proteins.. | |
| Protein Sequence | MSFGTRISRALRFLEIPVKNRASVNFLRNPDLQPIKSVNQTWGFWSNFAYWGVLSFNVGMWIGGSSALTVGLSYSETIGAFIIADLLTILFALANSCPGYDWKVGFTLAQRFVFGIYGSALGIIIRILMSIVYYGSNAWLGGLCVNMILDSWSHHYLHLPNTLSSKVAMTTKELIGFIIFHILTAFCYFMKPYHMNYILIWSCVGTFFAMLGMVIYLTKSAHGVGDLFTSTHSTVTGSKKAWAWVYTISYWYGSVSPGCTNQSDFSRFGSSNCAIWTGTIVALLIPATLIPVFGIIGASACEKLYGQTFWMPMDIFDNWLTTNYSAGARAATFFCGFCFVMSQISYTISNCGFASGMDLAGLLPKYVDIKRGAIFAACVSWACLPWNFYNSSSTFLTVMSSFGVVMTPIITVMICDNFLIRKRQYSVTNAFVLKGEYYFTKGVNWRAIVAWVCGMAPGLPGIAWEVNNDYFHNTGIINFFYGDSFFSFLISFFVYWGLCLLFPFKITVKHDDKDYYGAFTDEEARKKGMVPYSEISEEEIRAYTLGECFTSGHEYKPESSDDELPELTKTSSENTKVFEIVHQKDNEKESSTSSEKQIA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 533 | Phosphorylation | KKGMVPYSEISEEEI HCCCCCHHHCCHHHH | 23.53 | 28889911 | |
| 560 | Phosphorylation | HEYKPESSDDELPEL CCCCCCCCCCCCCHH | 47.63 | - | |
| 572 | Phosphorylation | PELTKTSSENTKVFE CHHHCCCCCCCEEEE | 39.85 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of THI72_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of THI72_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of THI72_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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