| UniProt ID | GOR1_YEAST | |
|---|---|---|
| UniProt AC | P53839 | |
| Protein Name | Glyoxylate reductase 1 | |
| Gene Name | GOR1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 350 | |
| Subcellular Localization | Cytoplasm. Nucleus. Mitochondrion. | |
| Protein Description | Reversibly reduces glyoxylate to glycolate.. | |
| Protein Sequence | MSKKPIVLKLGKDAFGDQAWGELEKIADVITIPESTTREQFLREVKDPQNKLSQVQVITRTARSVKNTGRFDEELALALPSSVVAVCHTGAGYDQIDVEPFKKRHIQVANVPDLVSNATADTHVFLLLGALRNFGIGNRRLIEGNWPEAGPACGSPFGYDPEGKTVGILGLGRIGRCILERLKPFGFENFIYHNRHQLPSEEEHGCEYVGFEEFLKRSDIVSVNVPLNHNTHHLINAETIEKMKDGVVIVNTARGAVIDEQAMTDALRSGKIRSAGLDVFEYEPKISKELLSMSQVLGLPHMGTHSVETRKKMEELVVENAKNVILTGKVLTIVPELQNEDWPNESKPLV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 12 | Acetylation | PIVLKLGKDAFGDQA CEEEEECCCCCCHHC | 57.21 | 24489116 | |
| 31 | Phosphorylation | EKIADVITIPESTTR HHHHCEEECCCCCCH | 30.26 | 22369663 | |
| 35 | Phosphorylation | DVITIPESTTREQFL CEEECCCCCCHHHHH | 29.71 | 22369663 | |
| 36 | Phosphorylation | VITIPESTTREQFLR EEECCCCCCHHHHHH | 28.36 | 22369663 | |
| 37 | Phosphorylation | ITIPESTTREQFLRE EECCCCCCHHHHHHH | 41.30 | 21440633 | |
| 155 | Phosphorylation | EAGPACGSPFGYDPE CCCCCCCCCCCCCCC | 19.55 | 27017623 | |
| 183 | Acetylation | RCILERLKPFGFENF HHHHHHCCCCCCCCC | 44.51 | 24489116 | |
| 252 | Phosphorylation | DGVVIVNTARGAVID CCEEEEECCCCCCCC | 13.56 | 23749301 | |
| 285 | Acetylation | DVFEYEPKISKELLS CEEECCCCCCHHHHC | 47.90 | 24489116 | |
| 288 | Acetylation | EYEPKISKELLSMSQ ECCCCCCHHHHCHHH | 56.72 | 24489116 | |
| 292 | Phosphorylation | KISKELLSMSQVLGL CCCHHHHCHHHHHCC | 29.07 | 22369663 | |
| 294 | Phosphorylation | SKELLSMSQVLGLPH CHHHHCHHHHHCCCC | 17.48 | 22369663 | |
| 304 | Phosphorylation | LGLPHMGTHSVETRK HCCCCCCCCCHHHHH | 11.91 | 22369663 | |
| 306 | Phosphorylation | LPHMGTHSVETRKKM CCCCCCCCHHHHHHH | 22.83 | 22369663 | |
| 309 | Phosphorylation | MGTHSVETRKKMEEL CCCCCHHHHHHHHHH | 45.71 | 22369663 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GOR1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GOR1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GOR1_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| PT122_YEAST | PET122 | physical | 16554755 | |
| NFT1_YEAST | NFT1 | physical | 16554755 | |
| IMG2_YEAST | IMG2 | genetic | 27708008 | |
| EMC5_YEAST | EMC5 | genetic | 27708008 | |
| TED1_YEAST | TED1 | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-31 AND SER-35, AND MASSSPECTROMETRY. | |
