| UniProt ID | HSL1_YEAST | |
|---|---|---|
| UniProt AC | P34244 | |
| Protein Name | Probable serine/threonine-protein kinase HSL1 | |
| Gene Name | HSL1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 1518 | |
| Subcellular Localization | Bud neck . | |
| Protein Description | ||
| Protein Sequence | MTGHVSKTSHVPKGRPSSLAKKAAKRAMAKVNSNPKRASGHLERVVQSVNDATKRLSQPDSTVSVATKSSKRKSRDTVGPWKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHPLIKKYDDLPVNKVLRKMRKDNMARGKSNSDLHLLNNVSPSIVTLHSKGEIDESILRSLQILWHGVSRELITAKLLQKPMSEEKLFYSLLLQYKQRHSISLSSSSENKKSATESSVNEPRIEYASKTANNTGLRSENNDVKTLHSLEIHSEDTSTVNQNNAITGVNTEINAPVLAQKSQFSINTLSQPESDKAEAEAVTLPPAIPIFNASSSRIFRNSYTSISSRSRRSLRLSNSRLSLSASTSRETVHDNEMPLPQLPKSPSRYSLSRRAIHASPSTKSIHKSLSRKNIAATVAARRTLQNSASKRSLYSLQSISKRSLNLNDLLVFDDPLPSKKPASENVNKSEPHSLESDSDFEILCDQILFGNALDRILEEEEDNEKERDTQRQRQNDTKSSADTFTISGVSTNKENEGPEYPTKIEKNQFNMSYKPSENMSGLSSFPIFEKENTLSSSYLEEQKPKRAALSDITNSFNKMNKQEGMRIEKKIQREQLQKKNDRPSPLKPIQHQELRVNSLPNDQGKPSLSLDPRRNISQPVNSKVESLLQGLKFKKEPASHWTHERGSLFMSEHVEDEKPVKASDVSIESSYVPLTTVATSSRDPSVLAESSTIQKPMLSLPSSFLNTSMTFKNLSQILADDGDDKHLSVPQNQSRSVAMSHPLRKQSAKISLTPRSNLNANLSVKRNQGSPGSYLSNDLDGISDMTFAMEIPTNTFTAQAIQLMNNDTDNNKINTSPKASSFTKEKVIKSAAYISKEKEPDNSDTNYIPDYTIPNTYDEKAINIFEDAPSDEGSLNTSSSESDSRASVHRKAVSIDTMATTNVLTPATNVRVSLYWNNNSSGIPRETTEEILSKLRLSPENPSNTHMQKRFSSTRGSRDSNALGISQSLQSMFKDLEEDQDGHTSQADILESSMSYSKRRPSEESVNPKQRVTMLFDEEEEESKKVGGGKIKEEHTKLDNKISEESSQLVLPVVEKKENANNTENNYSKIPKPSTIKVTKDTAMESNTQTHTKKPILKSVQNVEVEEAPSSDKKNWFVKLFQNFSSHNNATKASKNHVTNISFDDAHMLTLNEFNKNSIDYQLKNLDHKFGRKVVEYDCKFVKGNFKFKIKITSTPNASTVITVKKRSKHSNTSSNKAFEKFNDDVERVIRNAGRS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 39 | Phosphorylation | NSNPKRASGHLERVV CCCHHHHHHHHHHHH | 30.67 | 24961812 | |
| 48 | Phosphorylation | HLERVVQSVNDATKR HHHHHHHHHHHHHHH | 15.98 | 25704821 | |
| 54 | Ubiquitination | QSVNDATKRLSQPDS HHHHHHHHHHCCCCC | 53.73 | 17644757 | |
| 57 | Phosphorylation | NDATKRLSQPDSTVS HHHHHHHCCCCCCEE | 43.64 | 22369663 | |
| 61 | Phosphorylation | KRLSQPDSTVSVATK HHHCCCCCCEEEEEC | 37.07 | 22369663 | |
| 62 | Phosphorylation | RLSQPDSTVSVATKS HHCCCCCCEEEEECC | 24.95 | 22369663 | |
| 64 | Phosphorylation | SQPDSTVSVATKSSK CCCCCCEEEEECCCC | 13.21 | 22369663 | |
| 67 | Phosphorylation | DSTVSVATKSSKRKS CCCEEEEECCCCCCC | 29.33 | 22369663 | |
| 68 | Ubiquitination | STVSVATKSSKRKSR CCEEEEECCCCCCCC | 42.89 | 17644757 | |
| 69 | Phosphorylation | TVSVATKSSKRKSRD CEEEEECCCCCCCCC | 36.42 | 20377248 | |
| 70 | Phosphorylation | VSVATKSSKRKSRDT EEEEECCCCCCCCCC | 37.73 | 20377248 | |
| 130 | Phosphorylation | NNGTVPNSYSSSMVT CCCCCCCCCCCCCEE | 21.96 | 23749301 | |
| 131 | Phosphorylation | NGTVPNSYSSSMVTS CCCCCCCCCCCCEEC | 21.15 | 23749301 | |
| 133 | Phosphorylation | TVPNSYSSSMVTSNV CCCCCCCCCCEECCC | 17.77 | 23749301 | |
| 134 | Phosphorylation | VPNSYSSSMVTSNVS CCCCCCCCCEECCCC | 16.01 | 19779198 | |
| 141 | Phosphorylation | SMVTSNVSSPSIASR CCEECCCCCCCHHCC | 40.56 | 23749301 | |
| 142 | Phosphorylation | MVTSNVSSPSIASRE CEECCCCCCCHHCCC | 20.55 | 23749301 | |
| 151 | Phosphorylation | SIASREHSNHSQTNP CHHCCCCCCCCCCCC | 31.33 | 23749301 | |
| 154 | Phosphorylation | SREHSNHSQTNPYGI CCCCCCCCCCCCCCC | 42.84 | 23749301 | |
| 156 | Phosphorylation | EHSNHSQTNPYGIER CCCCCCCCCCCCCCH | 40.97 | 27738172 | |
| 273 | Phosphorylation | LPNKLLKTSCGSPHY CCHHHHHCCCCCCCC | 29.26 | 18768748 | |
| 331 | Ubiquitination | LLKVQSGKYQMPSNL HHHHHCCCCCCCCCC | 37.24 | 23749301 | |
| 332 | Phosphorylation | LKVQSGKYQMPSNLS HHHHCCCCCCCCCCC | 17.36 | 26447709 | |
| 336 | Phosphorylation | SGKYQMPSNLSSEAR CCCCCCCCCCCHHHH | 45.09 | 26447709 | |
| 339 | Phosphorylation | YQMPSNLSSEARDLI CCCCCCCCHHHHHHH | 30.31 | 26447709 | |
| 340 | Phosphorylation | QMPSNLSSEARDLIS CCCCCCCHHHHHHHH | 38.14 | 26447709 | |
| 347 | Phosphorylation | SEARDLISKILVIDP HHHHHHHHHHCCCCH | 22.42 | 26447709 | |
| 356 | Ubiquitination | ILVIDPEKRITTQEI HCCCCHHHCCCHHHH | 55.26 | 23749301 | |
| 393 | Ubiquitination | KDNMARGKSNSDLHL HCCCCCCCCHHHHHH | 40.69 | 17644757 | |
| 394 | Phosphorylation | DNMARGKSNSDLHLL CCCCCCCCHHHHHHH | 44.37 | 21440633 | |
| 396 | Phosphorylation | MARGKSNSDLHLLNN CCCCCCHHHHHHHHC | 48.95 | 21440633 | |
| 405 | Phosphorylation | LHLLNNVSPSIVTLH HHHHHCCCCCEEEEC | 18.30 | 24961812 | |
| 407 | Phosphorylation | LLNNVSPSIVTLHSK HHHCCCCCEEEECCC | 23.37 | 25752575 | |
| 410 | Phosphorylation | NVSPSIVTLHSKGEI CCCCCEEEECCCCCC | 19.65 | 21440633 | |
| 413 | Phosphorylation | PSIVTLHSKGEIDES CCEEEECCCCCCCHH | 45.53 | 28889911 | |
| 414 | Ubiquitination | SIVTLHSKGEIDESI CEEEECCCCCCCHHH | 50.22 | 17644757 | |
| 447 | Phosphorylation | KLLQKPMSEEKLFYS HHHCCCCCHHHHHHH | 51.65 | 28889911 | |
| 481 | Phosphorylation | KKSATESSVNEPRIE HHCCCCCCCCCHHHH | 23.80 | 21440633 | |
| 492 | Ubiquitination | PRIEYASKTANNTGL HHHHHCHHHCCCCCC | 43.41 | 15699485 | |
| 501 | Phosphorylation | ANNTGLRSENNDVKT CCCCCCCCCCCCCCE | 50.12 | 23749301 | |
| 507 | Ubiquitination | RSENNDVKTLHSLEI CCCCCCCCEEEEEEE | 48.51 | 15699485 | |
| 508 | Phosphorylation | SENNDVKTLHSLEIH CCCCCCCEEEEEEEE | 29.56 | 21440633 | |
| 511 | Phosphorylation | NDVKTLHSLEIHSED CCCCEEEEEEEECCC | 30.70 | 25752575 | |
| 516 | Phosphorylation | LHSLEIHSEDTSTVN EEEEEEECCCCCCCC | 42.71 | 21440633 | |
| 519 | Phosphorylation | LEIHSEDTSTVNQNN EEEECCCCCCCCCCC | 23.42 | 21551504 | |
| 520 | Phosphorylation | EIHSEDTSTVNQNNA EEECCCCCCCCCCCC | 42.55 | 21551504 | |
| 521 | Phosphorylation | IHSEDTSTVNQNNAI EECCCCCCCCCCCCC | 26.10 | 23749301 | |
| 544 | Phosphorylation | APVLAQKSQFSINTL HHHHHCCCCEEEECC | 25.11 | 19779198 | |
| 547 | Phosphorylation | LAQKSQFSINTLSQP HHCCCCEEEECCCCC | 13.80 | 28889911 | |
| 550 | Phosphorylation | KSQFSINTLSQPESD CCCEEEECCCCCCCC | 26.56 | 21551504 | |
| 556 | Phosphorylation | NTLSQPESDKAEAEA ECCCCCCCCHHHHHH | 51.61 | 19779198 | |
| 576 | Phosphorylation | AIPIFNASSSRIFRN CCCCCCCCCCCHHHC | 29.92 | 29734811 | |
| 584 | Phosphorylation | SSRIFRNSYTSISSR CCCHHHCCCCCCCCC | 26.07 | 22369663 | |
| 585 | Phosphorylation | SRIFRNSYTSISSRS CCHHHCCCCCCCCCC | 14.19 | 22369663 | |
| 586 | Phosphorylation | RIFRNSYTSISSRSR CHHHCCCCCCCCCCC | 21.29 | 22369663 | |
| 587 | Phosphorylation | IFRNSYTSISSRSRR HHHCCCCCCCCCCCH | 16.55 | 22369663 | |
| 589 | Phosphorylation | RNSYTSISSRSRRSL HCCCCCCCCCCCHHH | 21.33 | 23749301 | |
| 590 | Phosphorylation | NSYTSISSRSRRSLR CCCCCCCCCCCHHHH | 32.38 | 22369663 | |
| 595 | Phosphorylation | ISSRSRRSLRLSNSR CCCCCCHHHHHCCCC | 19.41 | 27017623 | |
| 599 | Phosphorylation | SRRSLRLSNSRLSLS CCHHHHHCCCCEEEC | 26.73 | 27017623 | |
| 601 | Phosphorylation | RSLRLSNSRLSLSAS HHHHHCCCCEEECCC | 31.09 | 23749301 | |
| 604 | Phosphorylation | RLSNSRLSLSASTSR HHCCCCEEECCCCCC | 21.11 | 23749301 | |
| 606 | Phosphorylation | SNSRLSLSASTSRET CCCCEEECCCCCCCC | 19.46 | 23749301 | |
| 608 | Phosphorylation | SRLSLSASTSRETVH CCEEECCCCCCCCCC | 24.44 | 23749301 | |
| 609 | Phosphorylation | RLSLSASTSRETVHD CEEECCCCCCCCCCC | 31.36 | 23749301 | |
| 610 | Phosphorylation | LSLSASTSRETVHDN EEECCCCCCCCCCCC | 26.14 | 25752575 | |
| 613 | Phosphorylation | SASTSRETVHDNEMP CCCCCCCCCCCCCCC | 23.25 | 23749301 | |
| 626 | Ubiquitination | MPLPQLPKSPSRYSL CCCCCCCCCCCCCCC | 81.32 | 15699485 | |
| 627 | Phosphorylation | PLPQLPKSPSRYSLS CCCCCCCCCCCCCCH | 26.60 | 25752575 | |
| 629 | Phosphorylation | PQLPKSPSRYSLSRR CCCCCCCCCCCCHHH | 51.44 | 20377248 | |
| 631 | Phosphorylation | LPKSPSRYSLSRRAI CCCCCCCCCCHHHHH | 20.50 | 23749301 | |
| 632 | Phosphorylation | PKSPSRYSLSRRAIH CCCCCCCCCHHHHHH | 20.82 | 28889911 | |
| 634 | Phosphorylation | SPSRYSLSRRAIHAS CCCCCCCHHHHHHCC | 17.49 | 24961812 | |
| 641 | Phosphorylation | SRRAIHASPSTKSIH HHHHHHCCCCCHHHH | 12.76 | 23749301 | |
| 643 | Phosphorylation | RAIHASPSTKSIHKS HHHHCCCCCHHHHHH | 46.07 | 25533186 | |
| 644 | Phosphorylation | AIHASPSTKSIHKSL HHHCCCCCHHHHHHH | 31.99 | 28152593 | |
| 646 | Phosphorylation | HASPSTKSIHKSLSR HCCCCCHHHHHHHCH | 29.98 | 28152593 | |
| 652 | Phosphorylation | KSIHKSLSRKNIAAT HHHHHHHCHHHHHHH | 48.58 | 21440633 | |
| 654 | Acetylation | IHKSLSRKNIAATVA HHHHHCHHHHHHHHH | 49.70 | 24489116 | |
| 654 | Ubiquitination | IHKSLSRKNIAATVA HHHHHCHHHHHHHHH | 49.70 | 17644757 | |
| 659 | Phosphorylation | SRKNIAATVAARRTL CHHHHHHHHHHHHHH | 11.14 | 25521595 | |
| 669 | Phosphorylation | ARRTLQNSASKRSLY HHHHHHCCCCCHHHH | 22.43 | 20377248 | |
| 671 | Phosphorylation | RTLQNSASKRSLYSL HHHHCCCCCHHHHHH | 28.55 | 20377248 | |
| 674 | Phosphorylation | QNSASKRSLYSLQSI HCCCCCHHHHHHHHH | 35.08 | 19779198 | |
| 677 | Phosphorylation | ASKRSLYSLQSISKR CCCHHHHHHHHHCCC | 25.81 | 21440633 | |
| 680 | Phosphorylation | RSLYSLQSISKRSLN HHHHHHHHHCCCCCC | 33.84 | 24961812 | |
| 682 | Phosphorylation | LYSLQSISKRSLNLN HHHHHHHCCCCCCHH | 27.54 | 20377248 | |
| 683 | Ubiquitination | YSLQSISKRSLNLND HHHHHHCCCCCCHHH | 44.32 | 17644757 | |
| 685 | Phosphorylation | LQSISKRSLNLNDLL HHHHCCCCCCHHHCE | 25.91 | 22369663 | |
| 747 | Ubiquitination | EEEEDNEKERDTQRQ HHHHHCHHHHHHHHH | 65.39 | 23749301 | |
| 765 | Phosphorylation | DTKSSADTFTISGVS HCCCCCCEEEEEECC | 23.53 | 28889911 | |
| 769 | Phosphorylation | SADTFTISGVSTNKE CCCEEEEEECCCCCC | 30.04 | 24961812 | |
| 772 | Phosphorylation | TFTISGVSTNKENEG EEEEEECCCCCCCCC | 29.77 | 23749301 | |
| 773 | Phosphorylation | FTISGVSTNKENEGP EEEEECCCCCCCCCC | 48.15 | 21440633 | |
| 782 | Phosphorylation | KENEGPEYPTKIEKN CCCCCCCCCCCCCCC | 21.24 | 27017623 | |
| 795 | Phosphorylation | KNQFNMSYKPSENMS CCCCCCCCCCCCCCC | 19.02 | 21440633 | |
| 802 | Phosphorylation | YKPSENMSGLSSFPI CCCCCCCCCCCCCCE | 48.43 | 21440633 | |
| 812 | Ubiquitination | SSFPIFEKENTLSSS CCCCEECCCCCCCHH | 45.58 | 17644757 | |
| 815 | Phosphorylation | PIFEKENTLSSSYLE CEECCCCCCCHHHHH | 29.16 | 28889911 | |
| 817 | Phosphorylation | FEKENTLSSSYLEEQ ECCCCCCCHHHHHHH | 18.39 | 19795423 | |
| 818 | Phosphorylation | EKENTLSSSYLEEQK CCCCCCCHHHHHHHC | 26.56 | 28889911 | |
| 819 | Phosphorylation | KENTLSSSYLEEQKP CCCCCCHHHHHHHCC | 30.29 | 23749301 | |
| 820 | Phosphorylation | ENTLSSSYLEEQKPK CCCCCHHHHHHHCCH | 21.78 | 24961812 | |
| 825 | Ubiquitination | SSYLEEQKPKRAALS HHHHHHHCCHHHHHH | 56.65 | 17644757 | |
| 827 | Ubiquitination | YLEEQKPKRAALSDI HHHHHCCHHHHHHHH | 62.80 | 17644757 | |
| 832 | Phosphorylation | KPKRAALSDITNSFN CCHHHHHHHHHHHHH | 23.41 | 24961812 | |
| 835 | Phosphorylation | RAALSDITNSFNKMN HHHHHHHHHHHHHHH | 29.78 | 21440633 | |
| 837 | Phosphorylation | ALSDITNSFNKMNKQ HHHHHHHHHHHHHHH | 22.88 | 21440633 | |
| 840 | Ubiquitination | DITNSFNKMNKQEGM HHHHHHHHHHHHHHH | 41.67 | 17644757 | |
| 860 | Ubiquitination | IQREQLQKKNDRPSP HHHHHHHHHCCCCCC | 63.24 | 17644757 | |
| 861 | Ubiquitination | QREQLQKKNDRPSPL HHHHHHHHCCCCCCC | 51.63 | 17644757 | |
| 866 | Phosphorylation | QKKNDRPSPLKPIQH HHHCCCCCCCCCCCC | 43.70 | 23749301 | |
| 869 | Ubiquitination | NDRPSPLKPIQHQEL CCCCCCCCCCCCCEE | 43.38 | 17644757 | |
| 880 | Phosphorylation | HQELRVNSLPNDQGK CCEEECCCCCCCCCC | 42.20 | 22369663 | |
| 887 | Ubiquitination | SLPNDQGKPSLSLDP CCCCCCCCCCCCCCC | 26.29 | 17644757 | |
| 891 | Phosphorylation | DQGKPSLSLDPRRNI CCCCCCCCCCCCCCC | 34.76 | 28889911 | |
| 899 | Phosphorylation | LDPRRNISQPVNSKV CCCCCCCCCCCHHHH | 31.79 | 21440633 | |
| 904 | Phosphorylation | NISQPVNSKVESLLQ CCCCCCHHHHHHHHH | 38.01 | 23749301 | |
| 905 | Ubiquitination | ISQPVNSKVESLLQG CCCCCHHHHHHHHHH | 44.83 | 17644757 | |
| 914 | Ubiquitination | ESLLQGLKFKKEPAS HHHHHHCCCCCCCCC | 63.06 | 17644757 | |
| 929 | Phosphorylation | HWTHERGSLFMSEHV CCCCCCCCCCCCCCC | 25.34 | 25704821 | |
| 945 | Phosphorylation | DEKPVKASDVSIESS CCCCCCHHHCEEECC | 32.59 | 24961812 | |
| 948 | Phosphorylation | PVKASDVSIESSYVP CCCHHHCEEECCEEC | 26.15 | 28889911 | |
| 951 | Phosphorylation | ASDVSIESSYVPLTT HHHCEEECCEECCEE | 25.87 | 21551504 | |
| 952 | Phosphorylation | SDVSIESSYVPLTTV HHCEEECCEECCEEE | 19.84 | 27017623 | |
| 963 | Phosphorylation | LTTVATSSRDPSVLA CEEEECCCCCHHHHH | 36.03 | 21551504 | |
| 967 | Phosphorylation | ATSSRDPSVLAESST ECCCCCHHHHHCCCC | 33.77 | 21551504 | |
| 990 | Phosphorylation | PSSFLNTSMTFKNLS CHHHCCCCCCCCCHH | 18.10 | 21440633 | |
| 992 | Phosphorylation | SFLNTSMTFKNLSQI HHCCCCCCCCCHHHH | 31.09 | 21440633 | |
| 994 | Ubiquitination | LNTSMTFKNLSQILA CCCCCCCCCHHHHHC | 48.05 | 17644757 | |
| 997 | Phosphorylation | SMTFKNLSQILADDG CCCCCCHHHHHCCCC | 25.27 | ||
| 1007 | Ubiquitination | LADDGDDKHLSVPQN HCCCCCCCCCCCCCC | 51.70 | 17644757 | |
| 1010 | Phosphorylation | DGDDKHLSVPQNQSR CCCCCCCCCCCCCCC | 31.32 | 25704821 | |
| 1027 | Ubiquitination | AMSHPLRKQSAKISL HHCCCCHHCCCCEEC | 57.18 | 17644757 | |
| 1033 | Phosphorylation | RKQSAKISLTPRSNL HHCCCCEECCCCCCC | 26.03 | 22369663 | |
| 1035 | Phosphorylation | QSAKISLTPRSNLNA CCCCEECCCCCCCCC | 15.18 | 22369663 | |
| 1038 | Phosphorylation | KISLTPRSNLNANLS CEECCCCCCCCCCEE | 47.04 | 19684113 | |
| 1045 | Phosphorylation | SNLNANLSVKRNQGS CCCCCCEEEECCCCC | 25.96 | 19684113 | |
| 1097 | Phosphorylation | TDNNKINTSPKASSF CCCCCCCCCCCCCCC | 50.29 | 27717283 | |
| 1098 | Phosphorylation | DNNKINTSPKASSFT CCCCCCCCCCCCCCC | 21.66 | 27717283 | |
| 1100 | Acetylation | NKINTSPKASSFTKE CCCCCCCCCCCCCHH | 61.75 | 22865919 | |
| 1100 | Ubiquitination | NKINTSPKASSFTKE CCCCCCCCCCCCCHH | 61.75 | 23749301 | |
| 1103 | Phosphorylation | NTSPKASSFTKEKVI CCCCCCCCCCHHHHH | 41.62 | 23749301 | |
| 1111 | Ubiquitination | FTKEKVIKSAAYISK CCHHHHHHHHHHCCC | 36.71 | 23749301 | |
| 1120 | Ubiquitination | AAYISKEKEPDNSDT HHHCCCCCCCCCCCC | 77.58 | 23749301 | |
| 1125 | Phosphorylation | KEKEPDNSDTNYIPD CCCCCCCCCCCCCCC | 53.87 | 28889911 | |
| 1129 | Phosphorylation | PDNSDTNYIPDYTIP CCCCCCCCCCCCCCC | 18.87 | 21440633 | |
| 1173 | Ubiquitination | SRASVHRKAVSIDTM CCHHHHHHCEEHHCC | 37.96 | 23749301 | |
| 1176 | Phosphorylation | SVHRKAVSIDTMATT HHHHHCEEHHCCCCC | 21.43 | 25752575 | |
| 1195 | Phosphorylation | PATNVRVSLYWNNNS CCCCEEEEEEECCCC | 12.74 | 19779198 | |
| 1202 | Phosphorylation | SLYWNNNSSGIPRET EEEECCCCCCCCCHH | 31.87 | 19779198 | |
| 1203 | Phosphorylation | LYWNNNSSGIPRETT EEECCCCCCCCCHHH | 42.75 | 25752575 | |
| 1209 | Phosphorylation | SSGIPRETTEEILSK CCCCCCHHHHHHHHH | 40.56 | 22369663 | |
| 1210 | Phosphorylation | SGIPRETTEEILSKL CCCCCHHHHHHHHHH | 27.20 | 22369663 | |
| 1215 | Phosphorylation | ETTEEILSKLRLSPE HHHHHHHHHHCCCCC | 34.99 | 22369663 | |
| 1220 | Phosphorylation | ILSKLRLSPENPSNT HHHHHCCCCCCCCCC | 24.59 | 19823750 | |
| 1225 | Phosphorylation | RLSPENPSNTHMQKR CCCCCCCCCCHHHHH | 66.98 | 20377248 | |
| 1227 | Phosphorylation | SPENPSNTHMQKRFS CCCCCCCCHHHHHHH | 24.06 | 27017623 | |
| 1231 | Ubiquitination | PSNTHMQKRFSSTRG CCCCHHHHHHHCCCC | 48.08 | 17644757 | |
| 1234 | Phosphorylation | THMQKRFSSTRGSRD CHHHHHHHCCCCCCC | 34.53 | 24961812 | |
| 1235 | Phosphorylation | HMQKRFSSTRGSRDS HHHHHHHCCCCCCCH | 21.29 | 24961812 | |
| 1236 | Phosphorylation | MQKRFSSTRGSRDSN HHHHHHCCCCCCCHH | 37.54 | 24961812 | |
| 1239 | Phosphorylation | RFSSTRGSRDSNALG HHHCCCCCCCHHHHH | 29.62 | 24961812 | |
| 1242 | Phosphorylation | STRGSRDSNALGISQ CCCCCCCHHHHHHHH | 23.92 | 24961812 | |
| 1248 | Phosphorylation | DSNALGISQSLQSMF CHHHHHHHHHHHHHH | 16.36 | 28889911 | |
| 1250 | Phosphorylation | NALGISQSLQSMFKD HHHHHHHHHHHHHHC | 22.91 | 28152593 | |
| 1253 | Phosphorylation | GISQSLQSMFKDLEE HHHHHHHHHHHCHHH | 31.32 | 24961812 | |
| 1266 | Phosphorylation | EEDQDGHTSQADILE HHCCCCCCCHHHHHH | 28.23 | 21440633 | |
| 1267 | Phosphorylation | EDQDGHTSQADILES HCCCCCCCHHHHHHH | 20.07 | 28889911 | |
| 1277 | Phosphorylation | DILESSMSYSKRRPS HHHHHHCCCCCCCCC | 28.36 | 27017623 | |
| 1279 | Phosphorylation | LESSMSYSKRRPSEE HHHHCCCCCCCCCCC | 16.63 | 27017623 | |
| 1284 | Phosphorylation | SYSKRRPSEESVNPK CCCCCCCCCCCCCHH | 52.78 | 25521595 | |
| 1287 | Phosphorylation | KRRPSEESVNPKQRV CCCCCCCCCCHHHHE | 24.12 | 19823750 | |
| 1325 | Phosphorylation | TKLDNKISEESSQLV HHHCHHCCHHHHHCE | 36.60 | 22369663 | |
| 1328 | Phosphorylation | DNKISEESSQLVLPV CHHCCHHHHHCEEEE | 21.23 | 22369663 | |
| 1329 | Phosphorylation | NKISEESSQLVLPVV HHCCHHHHHCEEEEE | 30.71 | 22369663 | |
| 1339 | Ubiquitination | VLPVVEKKENANNTE EEEEEEHHHCCCCCC | 42.57 | 23749301 | |
| 1359 | Acetylation | IPKPSTIKVTKDTAM CCCCCEEEECCCCHH | 43.89 | 25381059 | |
| 1362 | Ubiquitination | PSTIKVTKDTAMESN CCEEEECCCCHHHCC | 56.95 | 23749301 | |
| 1364 | Phosphorylation | TIKVTKDTAMESNTQ EEEECCCCHHHCCCC | 29.47 | 28889911 | |
| 1368 | Phosphorylation | TKDTAMESNTQTHTK CCCCHHHCCCCCCCC | 31.90 | 23749301 | |
| 1380 | Ubiquitination | HTKKPILKSVQNVEV CCCCCCHHEEEEEEC | 49.66 | 17644757 | |
| 1395 | Ubiquitination | EEAPSSDKKNWFVKL EECCCCCCCCHHHHH | 50.37 | 17644757 | |
| 1396 | Ubiquitination | EAPSSDKKNWFVKLF ECCCCCCCCHHHHHH | 65.48 | 17644757 | |
| 1401 | Ubiquitination | DKKNWFVKLFQNFSS CCCCHHHHHHHHHHC | 33.82 | 17644757 | |
| 1407 | Phosphorylation | VKLFQNFSSHNNATK HHHHHHHHCCCCCCH | 37.93 | 20377248 | |
| 1408 | Phosphorylation | KLFQNFSSHNNATKA HHHHHHHCCCCCCHH | 26.54 | 20377248 | |
| 1414 | Ubiquitination | SSHNNATKASKNHVT HCCCCCCHHHHCCCC | 48.53 | 17644757 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
| 1220 | S | Phosphorylation | Kinase | HOG1 | P32485 | GPS |
| - | K | Ubiquitination | E3 ubiquitin ligase | CDC20 | P26309 | PMID:22199232 |
| - | K | Ubiquitination | E3 ubiquitin ligase | CDC4 | P07834 | PMID:22199232 |
| - | K | Ubiquitination | E3 ubiquitin ligase | CDH1 | P53197 | PMID:22199232 |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HSL1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HSL1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-57; THR-273; SER-511;SER-610; SER-948; SER-1203; SER-1220; SER-1248; SER-1284; SER-1287 ANDSER-1325, AND MASS SPECTROMETRY. | |
| "Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-57; SER-1284; SER-1287;SER-1325; SER-1328 AND SER-1329, AND MASS SPECTROMETRY. | |
| "Analysis of phosphorylation sites on proteins from Saccharomycescerevisiae by electron transfer dissociation (ETD) massspectrometry."; Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.; Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-629; SER-643; SER-1220;SER-1284 AND SER-1287, AND MASS SPECTROMETRY. | |
