HGH1_YEAST - dbPTM
HGH1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HGH1_YEAST
UniProt AC P48362
Protein Name Protein HGH1
Gene Name HGH1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 394
Subcellular Localization
Protein Description
Protein Sequence MTSQLNELVEFLHSPQPAVRQIAIDNLVGFSAGPTSKVFKNDSYRPIKDIIKMIMDPEHGTRVIIQQGVTILVNLSEDKLVRNIILSDDKKFLKFLVWKIVDLTNPNADIMCILLSNLAKDDGILAVLNIKRNSSGEEVDDGLKLAALNKEVFKSLRAMDCLMDCFVKGYDKKLTKYASFNYLAFFFADISRFKLGRMYFIEEQEYDGVVPISKLLVFTEKYDAKVRREGVASTIKNSLFDSETHERLLKDEKINLLPYILLPIASAKDSEIDEEDMFNLPDELQLLPEDKERDPIPAIICCHLESILLLCTTHAGREYLRDKSVYPLVRELHKNVENEDIGELCYRIVNMLMRGEPGAGAVEEMPSKNAEEEEEEESEEEEDDDEEDEIVEVA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MTSQLNELV
------CCHHHHHHH		25.7722814378
37AcetylationFSAGPTSKVFKNDSY
CCCCCCCHHCCCCCC		54.9224489116
48AcetylationNDSYRPIKDIIKMIM
CCCCCCHHHHHHHHH		45.6224489116
91AcetylationIILSDDKKFLKFLVW
EECCCCHHHHHHHHH		64.0224489116
144AcetylationEEVDDGLKLAALNKE
CCCCHHHHHHHHCHH		41.4224489116
221AcetylationKLLVFTEKYDAKVRR
HEEEEECCCCHHHHH		45.4324489116
234PhosphorylationRREGVASTIKNSLFD
HHHHHHHHHHHHHCC		26.6619779198
238PhosphorylationVASTIKNSLFDSETH
HHHHHHHHHCCHHHH		25.9719779198
334AcetylationPLVRELHKNVENEDI
HHHHHHHHCCCCCCH		75.2724489116
378PhosphorylationEEEEEEESEEEEDDD
HHHHHHHHHCCCCCC		54.2928152593
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HGH1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HGH1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HGH1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
EF2_YEASTEFT2physical
14759368
HGH1_YEASTHGH1physical
14759368
EF2_YEASTEFT2physical
16554755
TCPZ_YEASTCCT6physical
16429126
DEP1_YEASTDEP1genetic
27708008
RS8A_YEASTRPS8Agenetic
27708008
RS8B_YEASTRPS8Agenetic
27708008
SWC5_YEASTSWC5genetic
27708008
ATU1_YEASTPCA1genetic
27708008
GIT1_YEASTGIT1genetic
27708008
FADH_YEASTSFA1genetic
27708008
TRS85_YEASTTRS85genetic
27708008
PMP3_YEASTPMP3genetic
27708008
IPK1_YEASTIPK1genetic
27708008
EF2_YEASTEFT2genetic
27708008
COG7_YEASTCOG7genetic
27708008
MED20_YEASTSRB2genetic
27708008
SDS3_YEASTSDS3genetic
27708008
VPS53_YEASTVPS53genetic
27708008
CYP7_YEASTCPR7genetic
27708008
CYT2_YEASTCYT2genetic
27708008
MSC3_YEASTMSC3genetic
27708008
ROM2_YEASTROM2genetic
27708008
COG8_YEASTCOG8genetic
27708008
HSC82_YEASTHSC82genetic
27708008
SCS7_YEASTSCS7genetic
27708008
COG6_YEASTCOG6genetic
27708008
MAS5_YEASTYDJ1genetic
27708008
SIN3_YEASTSIN3genetic
27708008
STI1_YEASTSTI1genetic
27708008
IDH2_YEASTIDH2genetic
27708008
RUD3_YEASTRUD3genetic
27708008
LHX4_HUMANLHX4physical
27107014
SRTD1_HUMANSERTAD1physical
27107014
MDM10_YEASTMDM10genetic
29674565
KPC1_YEASTPKC1genetic
29674565
THRC_YEASTTHR4genetic
29674565
PP2C1_YEASTPTC1genetic
29674565
SLX5_YEASTSLX5genetic
29674565
RS16A_YEASTRPS16Bgenetic
29674565
RS16B_YEASTRPS16Bgenetic
29674565
KIN28_YEASTKIN28genetic
29674565
RPC10_YEASTRPC11genetic
29674565
STN1_YEASTSTN1genetic
29674565
TRS23_YEASTTRS23genetic
29674565
SEM1_YEASTSEM1genetic
29674565
EF2_YEASTEFT2genetic
29674565
SAC7_YEASTSAC7genetic
29674565
EMI1_YEASTEMI1genetic
29674565
TSC11_YEASTTSC11genetic
29674565
COG7_YEASTCOG7genetic
29674565
MMS2_YEASTMMS2genetic
29674565
VAM7_YEASTVAM7genetic
29674565
RTG2_YEASTRTG2genetic
29674565
DPH1_YEASTDPH1genetic
29674565
ARP4_YEASTARP4genetic
29674565
CYP7_YEASTCPR7genetic
29674565
YJ9I_YEASTYJR141Wgenetic
29674565
FRMSR_YEASTYKL069Wgenetic
29674565
DPH2_YEASTDPH2genetic
29674565
IRS4_YEASTIRS4genetic
29674565
DPH6_YEASTDPH6genetic
29674565
RS30A_YEASTRPS30Agenetic
29674565
RS30B_YEASTRPS30Agenetic
29674565
COG8_YEASTCOG8genetic
29674565
PRP24_YEASTPRP24genetic
29674565
LCB1_YEASTLCB1genetic
29674565
PET8_YEASTPET8genetic
29674565
COG6_YEASTCOG6genetic
29674565
MAS5_YEASTYDJ1genetic
29674565
DCP2_YEASTDCP2genetic
29674565
CAP_YEASTSRV2genetic
29674565
PFD4_YEASTGIM3genetic
29674565
BRE5_YEASTBRE5genetic
29674565
SIN3_YEASTSIN3genetic
29674565
STI1_YEASTSTI1genetic
29674565
HSP7F_YEASTSSE1genetic
29674565
BEM4_YEASTBEM4genetic
29674565
ORC4_YEASTORC4genetic
29674565
MED10_YEASTNUT2genetic
29674565
COG3_YEASTCOG3genetic
29674565
SIC1_YEASTSIC1genetic
29674565
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HGH1_YEAST

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Related Literatures of Post-Translational Modification

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