| UniProt ID | GIT1_YEAST | |
|---|---|---|
| UniProt AC | P25346 | |
| Protein Name | Glycerophosphoinositol transporter 1 {ECO:0000303|PubMed:9691030} | |
| Gene Name | GIT1 {ECO:0000303|PubMed:9691030} | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 518 | |
| Subcellular Localization |
Cell membrane Multi-pass membrane protein . |
|
| Protein Description | Glycerophosphodiester transporter that mediates uptake of both glycerophosphoinositol (GroPIns) and glycerophosphocholine (GroPCho) as sources of the nutrients inositol and phosphate. [PubMed: 9691030] | |
| Protein Sequence | MEDKDITSVNEKEVNENTNPRIIKYDAERRATRTETSKKDKWKNIVTIIASGFALISDGYVNGSMSMLNKVFVMEYGKKNYSSKVSTRVSNAALVGIIFGQFFMGIAADYYSRKSCILVATAILVIGSALCAASHGTTVPGMFWMLTVMRGLVGIGVGAEYPTSTLSANESANEYTTTKRGGILVMVTNLPLAFGGPFATIIFLIVYKICSGTKHLEAIWRTVFAIGCFWPLSVFYFRWKTATTEVYEKGRIKRNIPYFLALKFYWKRLLGTCGTWFMYDFVTFPNGIFSSTIISSVIKDQNDLVKVAEWNLLLGVLAVLGVPIGAYLSDRIGRKYTLMFGFSGYIIFGLIIGCAYDQLKKITPLFIIFYAFMNMLGNAGPGDMLGVISSEASATAVRGVFYGLSAVTGKIGSVVGVECFQPIRDNLGARWTFIIAAICGLIGIIITYFFVPHSLESDLMKQDVEFHNYLVSNGWTGKMGFDETDEESMVRTIEVEENGTNCSKKNAEIISVRQVDQS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | Phosphorylation | -MEDKDITSVNEKEV -CCCCCCCCCCHHHC | 36.43 | 28152593 | |
| 8 | Phosphorylation | MEDKDITSVNEKEVN CCCCCCCCCCHHHCC | 24.23 | 28152593 | |
| 80 | N-linked_Glycosylation | VMEYGKKNYSSKVST HHHHCCCCCCCCHHH | 45.46 | - | |
| 81 | Phosphorylation | MEYGKKNYSSKVSTR HHHCCCCCCCCHHHH | 24.17 | 27017623 | |
| 82 | Phosphorylation | EYGKKNYSSKVSTRV HHCCCCCCCCHHHHH | 32.83 | 27017623 | |
| 86 | Phosphorylation | KNYSSKVSTRVSNAA CCCCCCHHHHHHHHH | 17.77 | 27017623 | |
| 360 | Ubiquitination | GCAYDQLKKITPLFI HHHHHHHHHHHHHHH | 36.17 | 17644757 | |
| 361 | Ubiquitination | CAYDQLKKITPLFII HHHHHHHHHHHHHHH | 61.48 | 17644757 | |
| 484 | Phosphorylation | GKMGFDETDEESMVR CCCCCCCCCCHHCEE | 51.02 | 28889911 | |
| 488 | Phosphorylation | FDETDEESMVRTIEV CCCCCCHHCEEEEEE | 22.11 | 28152593 | |
| 492 | Phosphorylation | DEESMVRTIEVEENG CCHHCEEEEEEEECC | 15.30 | 28889911 | |
| 500 | Phosphorylation | IEVEENGTNCSKKNA EEEEECCCCCCCCCC | 44.63 | 28889911 | |
| 503 | Phosphorylation | EENGTNCSKKNAEII EECCCCCCCCCCEEE | 49.05 | 28889911 | |
| 511 | Phosphorylation | KKNAEIISVRQVDQS CCCCEEEEEEEECCC | 19.53 | 22369663 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GIT1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GIT1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GIT1_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| PHO88_YEAST | PHO88 | physical | 16093310 | |
| ASI3_YEAST | ASI3 | physical | 16093310 | |
| DIP5_YEAST | DIP5 | physical | 16093310 | |
| SLM2_YEAST | SLM2 | genetic | 20526336 | |
| CALM_YEAST | CMD1 | genetic | 27708008 | |
| RPB1_YEAST | RPO21 | genetic | 27708008 | |
| ERF3_YEAST | SUP35 | genetic | 27708008 | |
| NEP1_YEAST | EMG1 | genetic | 27708008 | |
| AFG2_YEAST | AFG2 | genetic | 27708008 | |
| MCM1_YEAST | MCM1 | genetic | 27708008 | |
| MED11_YEAST | MED11 | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
