POG1_YEAST - dbPTM
POG1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID POG1_YEAST
UniProt AC P40473
Protein Name Transcriptional activator POG1
Gene Name POG1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 351
Subcellular Localization Nucleus .
Protein Description Transcriptional activator which promotes cell cycle recovery with CLN2, after pheromone induced G1 arrest, probably inhibiting the ability of STE20 to activate the pheromone response pathway. Binds the promoters of genes that function in cell cycle regulation, cytoskeletal organization, and spindle assembly. May also be involved in stress-resistance..
Protein Sequence MKQEPHRQSEEKEKPKGPMAVEREQHTSLSSGTTVTASTGDESTNSRPVESSQTEKSLSLRIRILKQLGFDDIQELNACDTGLVEQFLNVRLINDTKELEKIRESNLAKLNQIIDKCMESDKISDSTLNKILDMSMNRDTNNDNNNHLTIPSPITTKKRKINASELASPRGHRRYRSDIPTVSEVETGVGYPQIHQQPGAYTLPMPANQWMSNPYMQPPQPQVQQIMPQYLYPPGMGPQAQLPTMSSNSESQTPVMSSQFLSLNQHGLYQQNIGAHPVMSMGPQANIYGQQHQLQPGQERDQSRKSFSHRRSQSANISMANFRSPMRNPQPASSQRPVNFLIHTPKHPPPT
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
9PhosphorylationKQEPHRQSEEKEKPK
CCCCCCCCCCCCCCC		47.9130377154
140PhosphorylationDMSMNRDTNNDNNNH
HHHHCCCCCCCCCCC		32.4629136822
149PhosphorylationNDNNNHLTIPSPITT
CCCCCCCCCCCCCCC		24.2424961812
152PhosphorylationNNHLTIPSPITTKKR
CCCCCCCCCCCCCCC		25.6922369663
155PhosphorylationLTIPSPITTKKRKIN
CCCCCCCCCCCCCCC		35.6322369663
156PhosphorylationTIPSPITTKKRKINA
CCCCCCCCCCCCCCH		34.9822369663
164PhosphorylationKKRKINASELASPRG
CCCCCCHHHHCCCCC		28.7629136822
168PhosphorylationINASELASPRGHRRY
CCHHHHCCCCCCCCC		27.9622369663
312PhosphorylationKSFSHRRSQSANISM
HHHHHHHHHCCCCCC		28.5722369663
314PhosphorylationFSHRRSQSANISMAN
HHHHHHHCCCCCCCC		25.2422369663
318PhosphorylationRSQSANISMANFRSP
HHHCCCCCCCCCCCC		16.2022369663
334PhosphorylationRNPQPASSQRPVNFL
CCCCCCCCCCCCEEE		32.1119779198
344PhosphorylationPVNFLIHTPKHPPPT
CCEEEEECCCCCCCC		27.3419779198
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of POG1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of POG1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of POG1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
POG1_YEASTPOG1physical
11967834
AP18A_YEASTYAP1801physical
18719252
POG1_YEASTPOG1physical
18719252
IES1_YEASTIES1genetic
20959818
CG13_YEASTCLN3genetic
9927449
BCK1_YEASTBCK1genetic
9927449
MSG5_YEASTMSG5genetic
9927449
DMA2_YEASTDMA2physical
25073408
AVT5_YEASTAVT5genetic
27708008
TPS1_YEASTTPS1genetic
27708008
STE50_YEASTSTE50genetic
27708008
NAA38_YEASTMAK31genetic
27708008
PEX19_YEASTPEX19genetic
27708008
WDR59_YEASTMTC5genetic
27708008
MNN10_YEASTMNN10genetic
27708008
YD249_YEASTYDR249Cgenetic
27708008
GET2_YEASTGET2genetic
27708008
BLM10_YEASTBLM10genetic
27708008
GTS1_YEASTGTS1genetic
27708008
PSA3_YEASTPRE9genetic
27708008
SMI1_YEASTSMI1genetic
27708008
YMW4_YEASTYMR074Cgenetic
27708008
SHH3_YEASTSHH3genetic
27708008
ASI1_YEASTASI1genetic
27708008
ALG12_YEASTALG12genetic
27708008
PHO80_YEASTPHO80genetic
27708008
TAT2_YEASTTAT2genetic
27708008
PMG3_YEASTGPM3genetic
27708008
YO012_YEASTYOR012Wgenetic
27708008
LEO1_YEASTLEO1genetic
27708008
SLY41_YEASTSLY41genetic
27708008
CIN1_YEASTCIN1genetic
27708008
ELOC_YEASTELC1genetic
27708008
BEM4_YEASTBEM4genetic
27708008
OXR1_YEASTOXR1genetic
27708008
ATG13_YEASTATG13genetic
27708008
UBC9_HUMANUBE2Iphysical
27107014
RBPMS_HUMANRBPMSphysical
27107014
CA094_HUMANC1orf94physical
27107014
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of POG1_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-152, AND MASSSPECTROMETRY.

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