ELOC_YEAST - dbPTM
ELOC_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ELOC_YEAST
UniProt AC Q03071
Protein Name Elongin-C
Gene Name ELC1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 99
Subcellular Localization Cytoplasm . Nucleus .
Protein Description Prevents degradation of interacting proteins like PCL6 by the proteasome..
Protein Sequence MSQDFVTLVSKDDKEYEISRSAAMISPTLKAMIEGPFRESKGRIELKQFDSHILEKAVEYLNYNLKYSGVSEDDDEIPEFEIPTEMSLELLLAADYLSI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MSQDFVTLV
------CCCCCEEEE
38.1622814378
2Phosphorylation------MSQDFVTLV
------CCCCCEEEE
38.1622369663
7Phosphorylation-MSQDFVTLVSKDDK
-CCCCCEEEEECCCC
22.8022369663
26PhosphorylationSRSAAMISPTLKAMI
CHHHHHHCHHHHHHH
9.9619779198
28PhosphorylationSAAMISPTLKAMIEG
HHHHHCHHHHHHHHC
33.8219779198
60PhosphorylationILEKAVEYLNYNLKY
HHHHHHHHHHHCCEE
8.1422369663
63PhosphorylationKAVEYLNYNLKYSGV
HHHHHHHHCCEECCC
21.1922369663

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ELOC_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ELOC_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ELOC_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
AAKG_YEASTSNF4physical
10760578
PCL6_YEASTPCL6physical
10760578
YAP4_YEASTCIN5physical
10760578
ELOA1_YEASTELA1physical
10753924
RAD16_YEASTRAD16physical
15226437
RAD7_YEASTRAD7physical
15226437
ELOC_YEASTELC1physical
10430890
RAD18_YEASTRAD18genetic
16705154
RAD52_YEASTRAD52genetic
16705154
MED5_YEASTNUT1genetic
17314980
JHD2_YEASTJHD2genetic
17314980
GCN1_YEASTGCN1genetic
17314980
ACT_YEASTACT1genetic
17314980
BRE5_YEASTBRE5genetic
17314980
COPE_YEASTSEC28genetic
17314980
DOA1_YEASTDOA1genetic
17314980
YPT6_YEASTYPT6genetic
17314980
MFG1_YEASTMFG1genetic
20093466
NHP10_YEASTNHP10genetic
20093466
TPS2_YEASTTPS2genetic
20093466
BLM10_YEASTBLM10genetic
20093466
MSH4_YEASTMSH4genetic
20093466
UBR1_YEASTUBR1genetic
20093466
YIQ6_YEASTYIL166Cgenetic
20093466
PHO86_YEASTPHO86genetic
20093466
ELF1_YEASTELF1genetic
20093466
FABG_YEASTOAR1genetic
20093466
MSC1_YEASTMSC1genetic
20093466
TOM70_YEASTTOM70genetic
20093466
MSH2_YEASTMSH2genetic
20093466
RU2A_YEASTLEA1genetic
20093466
RAD5_YEASTRAD5genetic
16705154
RAD26_YEASTRAD26genetic
16705154
CUL3_YEASTCUL3physical
19920177
RAD7_YEASTRAD7physical
19920177
RAD16_YEASTRAD16physical
19920177
RPB1_YEASTRPO21physical
19920177
VHL_HUMANVHLphysical
11545595
DEF1_YEASTDEF1physical
23993092
ELOA1_YEASTELA1physical
23993092
RPB1_YEASTRPO21physical
23993092
YAP6_YEASTYAP6physical
10760578
CBF1_YEASTCBF1physical
10760578
MDJ1_YEASTMDJ1physical
10760578
VHL_HUMANVHLphysical
10998253
RAD7_YEASTRAD7physical
11805837
NHP10_YEASTNHP10genetic
27708008
GPR1_YEASTGPR1genetic
27708008
TPS2_YEASTTPS2genetic
27708008
RV167_YEASTRVS167genetic
27708008
MSH4_YEASTMSH4genetic
27708008
THIK_YEASTPOT1genetic
27708008
YIQ6_YEASTYIL166Cgenetic
27708008
PHO86_YEASTPHO86genetic
27708008
YJ24_YEASTKCH1genetic
27708008
FABG_YEASTOAR1genetic
27708008
YL415_YEASTYLR415Cgenetic
27708008
MSC1_YEASTMSC1genetic
27708008
HMI1_YEASTHMI1genetic
27708008
MDJ1_YEASTMDJ1genetic
27453043
ERG1_YEASTERG1genetic
27453043
AAD4_YEASTAAD4genetic
27453043
SNF2_YEASTSNF2genetic
27453043
VPS53_YEASTVPS53genetic
27453043
IME1_YEASTIME1genetic
27453043
ESS1_YEASTESS1genetic
27453043
TOR2_YEASTTOR2genetic
27453043
RL11B_YEASTRPL11Bgenetic
29674565
APC11_YEASTAPC11genetic
29674565
COG3_YEASTCOG3genetic
29674565
ICE2_YEASTICE2genetic
29674565
YPK3_YEASTYPK3genetic
29674565
RRP8_YEASTRRP8genetic
29674565
SAC3_YEASTSAC3genetic
29674565
PAD1_YEASTPAD1genetic
29674565
BLM10_YEASTBLM10genetic
29674565
PIB2_YEASTPIB2genetic
29674565
PHB2_YEASTPHB2genetic
29674565
SOL4_YEASTSOL4genetic
29674565
BTN1_YEASTYHC3genetic
29674565
ISY1_YEASTISY1genetic
29674565
CDC11_YEASTCDC11genetic
29674565
LAC1_YEASTLAC1genetic
29674565
ELM1_YEASTELM1genetic
29674565
BCH2_YEASTBCH2genetic
29674565
YCT1_YEASTYCT1genetic
29674565
SCS7_YEASTSCS7genetic
29674565

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ELOC_YEAST

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Related Literatures of Post-Translational Modification

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