dbPTM

SOL4_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SOL4_YEAST
UniProt AC	P53315
Protein Name	6-phosphogluconolactonase 4
Gene Name	SOL4
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	255
Subcellular Localization	Cytoplasm. Nucleus.
Protein Description	Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate..
Protein Sequence	MVKLQRFSEKKSLIHEFGKFILEKQESALTGDADAVFNIAISGGSMNQALYESLVNDKNIFPHIKWPQWRIFFCDERLVPFEDPQSNYGQFKKTVLDPLVHQGNQLNLGPTVYTINESLIGGGETANRKIAEEYASMLPASFDLILLGCGEDGHTCSLFPGVEFNYLVEEMDRKVLWCNNSPKAPKDRITFTLAVVAEAKSVCFLVRGAAKKAIMHDVLIVKNSELPSVLVNEMVGTKVTWFLDDEAGALIPENC

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	QRFSEKKSLIHEFGK CCHHHHHHHHHHHHH	43.56	20377248
19	Acetylation	SLIHEFGKFILEKQE HHHHHHHHHHHHHHH	34.25	24489116
174	Ubiquitination	LVEEMDRKVLWCNNS HHHHCCCCEEEECCC	37.10	23749301

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SOL4_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SOL4_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SOL4_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ROD1_YEAST	ROD1	physical	16554755
DEP1_YEAST	DEP1	genetic	20093466
CHL4_YEAST	CHL4	genetic	20093466
SSD1_YEAST	SSD1	genetic	20093466
PT122_YEAST	PET122	genetic	20093466
COX23_YEAST	COX23	genetic	20093466
SOL3_YEAST	SOL3	genetic	20093466
YJ24_YEAST	KCH1	genetic	20093466
AP2S_YEAST	APS2	genetic	20093466
DHOM_YEAST	HOM6	genetic	20093466
SAC1_YEAST	SAC1	genetic	20093466
HAP4_YEAST	HAP4	genetic	20093466
LHS1_YEAST	LHS1	genetic	20093466
NAH1_YEAST	NHA1	genetic	20093466
VRP1_YEAST	VRP1	genetic	20093466
MSS1_YEAST	MSS1	genetic	20093466
PFKA2_YEAST	PFK2	genetic	20093466
ODP2_YEAST	LAT1	genetic	20093466
COX5A_YEAST	COX5A	genetic	20093466
ATG3_YEAST	ATG3	genetic	20093466
ATP23_YEAST	ATP23	genetic	20093466
CYC2_YEAST	CYC2	genetic	20093466
G3P1_YEAST	TDH1	genetic	21623372
COQ2_YEAST	COQ2	genetic	21623372
ADE_YEAST	AAH1	genetic	21623372
ATP10_YEAST	ATP10	genetic	27708008
TFB1_YEAST	TFB1	genetic	27708008
FIP1_YEAST	FIP1	genetic	27708008
YJ9I_YEAST	YJR141W	genetic	27708008
SNF1_YEAST	SNF1	genetic	27708008
COX23_YEAST	COX23	genetic	27708008
SOL3_YEAST	SOL3	genetic	27708008
SDS3_YEAST	SDS3	genetic	27708008
LPLA_YEAST	AIM22	genetic	27708008
YJ24_YEAST	KCH1	genetic	27708008
DHOM_YEAST	HOM6	genetic	27708008
HAP4_YEAST	HAP4	genetic	27708008
SAC1_YEAST	SAC1	genetic	27708008
RIC1_YEAST	RIC1	genetic	27708008
PUS5_YEAST	PUS5	genetic	27708008
VRP1_YEAST	VRP1	genetic	27708008
RCF1_YEAST	RCF1	genetic	27708008
MAC1_YEAST	MAC1	genetic	27708008
MSS1_YEAST	MSS1	genetic	27708008
SAP30_YEAST	SAP30	genetic	27708008
COX5A_YEAST	COX5A	genetic	27708008
ODP2_YEAST	LAT1	genetic	27708008
ATP23_YEAST	ATP23	genetic	27708008
CYC2_YEAST	CYC2	genetic	27708008
GLO4_YEAST	GLO4	genetic	27708008
FABD_YEAST	MCT1	genetic	27708008
MNE1_YEAST	MNE1	genetic	27708008
HAP5_YEAST	HAP5	genetic	27708008
MSS18_YEAST	MSS18	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SOL4_YEAST

Related Literatures of Post-Translational Modification