| UniProt ID | MDJ1_YEAST | |
|---|---|---|
| UniProt AC | P35191 | |
| Protein Name | DnaJ homolog 1, mitochondrial | |
| Gene Name | MDJ1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 511 | |
| Subcellular Localization | Mitochondrion. | |
| Protein Description | Plays a role in mitochondrial biogenesis and protein folding.. | |
| Protein Sequence | MAFQQGVLSRCSGVFRHHVGHSRHINNILYRHAIAFASIAPRIPKSSFHTSAIRNNEAFKDPYDTLGLKKSATGAEIKKAYYKLAKKYHPDINKEPDAEKKFHDLQNAYEILSDETKRQQYDQFGPAAFGGGGAAGGAGGGSGSPFGSQFHDFSGFTSAGGSPFGGINFEDLFGAAFGGGGRGSGGASRSSSMFRQYRGDPIEIVHKVSFKDAVFGSKNVQLRFSALDPCSTCSGTGMKPNTHKVSCSTCHGTGTTVHIRGGFQMMSTCPTCNGEGTMKRPQDNCTKCHGEGVQVNRAKTITVDLPHGLQDGDVVRIPGQGSYPDIAVEADLKDSVKLSRGDILVRIRVDKDPNFSIKNKYDIWYDKEIPITTAALGGTVTIPTVEGQKIRIKVAPGTQYNQVISIPNMGVPKTSTIRGDMKVQYKIVVKKPQSLAEKCLWEALADVTNDDMAKKTMQPGTAAGTAINEEILKKQKQEEEKHAKKDDDNTLKRLENFITNTFRKIKGDKKN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 38 | Phosphorylation | RHAIAFASIAPRIPK HHHHHHHHHCCCCCH | 16.90 | 28889911 | |
| 207 | Acetylation | DPIEIVHKVSFKDAV CCEEEEEEEEHHHHC | 28.78 | 24489116 | |
| 211 | Acetylation | IVHKVSFKDAVFGSK EEEEEEHHHHCCCCC | 36.95 | 24489116 | |
| 211 | Succinylation | IVHKVSFKDAVFGSK EEEEEEHHHHCCCCC | 36.95 | 23954790 | |
| 248 | Phosphorylation | NTHKVSCSTCHGTGT CCCEEEEEECCCCCC | 26.94 | 27017623 | |
| 253 | Phosphorylation | SCSTCHGTGTTVHIR EEEECCCCCCEEEEC | 14.00 | 27017623 | |
| 271 | Phosphorylation | QMMSTCPTCNGEGTM EEEEECCCCCCCCCC | 22.28 | 27017623 | |
| 277 | Phosphorylation | PTCNGEGTMKRPQDN CCCCCCCCCCCCCCC | 18.41 | 27017623 | |
| 300 | Phosphorylation | VQVNRAKTITVDLPH EECCCCEEEEEECCC | 22.39 | 28889911 | |
| 351 | Acetylation | LVRIRVDKDPNFSIK EEEEEECCCCCCCCC | 72.70 | 24489116 | |
| 356 | Phosphorylation | VDKDPNFSIKNKYDI ECCCCCCCCCCCEEE | 39.01 | 22369663 | |
| 360 | Acetylation | PNFSIKNKYDIWYDK CCCCCCCCEEEEECC | 39.02 | 24489116 | |
| 361 | Phosphorylation | NFSIKNKYDIWYDKE CCCCCCCEEEEECCC | 23.27 | 30377154 | |
| 365 | Phosphorylation | KNKYDIWYDKEIPIT CCCEEEEECCCCCCE | 19.92 | 30377154 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MDJ1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MDJ1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MDJ1_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MDJ1_YEAST | MDJ1 | physical | 11967834 | |
| GRPE_YEAST | MGE1 | physical | 9155010 | |
| HSP77_YEAST | SSC1 | physical | 8943361 | |
| MDJ2_YEAST | MDJ2 | genetic | 9325105 | |
| SCC4_YEAST | SCC4 | physical | 16554755 | |
| HSP77_YEAST | SSC1 | physical | 14605210 | |
| HSP77_YEAST | SSC1 | physical | 20385092 | |
| HOME3_HUMAN | HOMER3 | physical | 27107014 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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