| UniProt ID | SCC4_YEAST | |
|---|---|---|
| UniProt AC | P40090 | |
| Protein Name | MAU2 chromatid cohesion factor homolog | |
| Gene Name | SCC4 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 624 | |
| Subcellular Localization | Nucleus . Associates with chromatin. | |
| Protein Description | Involved in sister chromatid cohesion. [PubMed: 10882066 Forms a complex with SCC2, which is required for the association of the cohesin complex with chromosomes] | |
| Protein Sequence | MENLGDKLSISQVYHLAQEYRDHAYSIANKIGSEEGLKQYYGLMNMSIQMFQLLKTKCTLSVLEDSKVTFEMVELLIQETYNFDLAELYISSLKERLQTHQSDTDLVEEIMRCEFLLLHDLPLMRDSKFHYKIALRNCNELVQYMVNLQDELYQNWASVFQYVGVMLCIKLKQHRRVKTSFHGLLSQCREKSQWKWFLNLCYVNYLLNERFPIPEDALQELRSTELHTVGPELYAWKLALEMVIQLCKDGNITDHLNEFKNFFDTNKQSLVTNEGKGCVIKIMPRIALKVELPMIFHYKELKNILLLLQSVSYIVNCYDEKGNFSRKFLPKVYSTTQKLIKNIAAGGVSMNELDSRIQTYKSILEFCEFYKVWEQTLLKGAVVTTESPKLGPSPGYVRLLQAMKVQFEGGGAVEEYTRLAQSGGTSSEVKMISLLNCYTVQAARVSRCSGDKQGELVEQCNKVWLQVEKLLQETDLQFNPIWECTVTILWLFSHFEPFSWNPLPCSDKQRAEYVSKLREFYSSNKFVAGEAVADNRFKLKKALLLQILVNYLGGRMLEHDLGEIYAISAKCFDMCRQQGGMRKVQYVIGIWHLMNCTVAMRGKDVALTNAKLEALVKQITSVKQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 40 | Phosphorylation | SEEGLKQYYGLMNMS CHHHHHHHHHHHHHH | 9.64 | 28889911 | |
| 41 | Phosphorylation | EEGLKQYYGLMNMSI HHHHHHHHHHHHHHH | 10.99 | 28889911 | |
| 47 | Phosphorylation | YYGLMNMSIQMFQLL HHHHHHHHHHHHHHH | 12.50 | 28889911 | |
| 56 | Phosphorylation | QMFQLLKTKCTLSVL HHHHHHHCCCCHHHH | 31.18 | 28889911 | |
| 180 | Phosphorylation | QHRRVKTSFHGLLSQ HHCCCHHCHHHHHHH | 14.99 | 19779198 | |
| 385 | Phosphorylation | LKGAVVTTESPKLGP CCCCEEECCCCCCCC | 23.90 | 27717283 | |
| 387 | Phosphorylation | GAVVTTESPKLGPSP CCEEECCCCCCCCCC | 25.83 | 23749301 | |
| 393 | Phosphorylation | ESPKLGPSPGYVRLL CCCCCCCCCHHHHHH | 29.20 | 28889911 | |
| 433 | Phosphorylation | SSEVKMISLLNCYTV CHHHHHHHHHCCEEE | 24.25 | 29688323 | |
| 438 | Phosphorylation | MISLLNCYTVQAARV HHHHHCCEEEHHHHH | 14.63 | 29688323 | |
| 439 | Phosphorylation | ISLLNCYTVQAARVS HHHHCCEEEHHHHHH | 14.35 | 29688323 | |
| 446 | Phosphorylation | TVQAARVSRCSGDKQ EEHHHHHHCCCCCCC | 23.24 | 29688323 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SCC4_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SCC4_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SCC4_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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