YL001_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YL001_YEAST
• UniProt AC: Q07895
• Protein Name: FAS1 domain-containing protein YLR001C
• Gene Name: YLR001C
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 862
• Subcellular Localization: Vacuole membrane ; Single-pass type I membrane protein .
• Protein Sequence: MNMAIQTIKYIFWLLPILGLTQALLQNPGDDFPFSTVIDILSENVEFSTFLRIIQKTGHVQYLNELQNFTLFAPINSAFIKGDQTTDQFEEHFHIEDFLIHDRVLQVRDLENGTYLEKRAAKAPLLLRKHERHCFVNEIAVVEPDLLPSFQNASLQGINNLLLIQPQINELLVQLDEETQDLKIFSDFISSFSNYNAYTNSSTVLVPLDVNFRKFFNTIEINYLLDKYNKLGKSNTISQAKWAADRTSLLQELIIDDVYGGILPKELILENKNNRKLFMKSNSEGTSVSVNNSDYSPISNRIFEIGVVHGFSDLDFLRTHIQFDAEKYLHGLNCSEFVKELYFRDLEKFIQNGRKITIFVPQASFNEDRGYTKPSLLYHFVEGKIDLEQDFSSLRPIQYAPTQIYDSAFCSSAKRLGGHCQKFKITRSNKGYYINGRFKILNTKPYEIGNTSIYSIDDDLQLPGDLVLSLAPENHCSISLMLLKELNLLDLPSNHKGYTILLPCMNSWDNNDLTIDYLRSNKTALNLLMRNLIFEDLIYSNNYSISTTVKNLYGNSVSIGVQKIVGSQNLTKISVSTIKESIIIEESSDIFFNQGVIHPIDQLDFPVDLEISLKELIETTGTKEIFDFFNLFYDLSSIIWNNEEYSLLVPTASSIPLSGITANSTNLRKFLELHLIPANVTQNLLDCNGSISTKLGTKLNCRKDHLDNVFVSIQGDWTKEVRVLKTGCTTNLKSSCIFLIDKPISLSWLNSEKYHLRLPGIAVGFGVIIGVTIAISLLFCIIITRGGKVKDKNQRGRNDRATTPLIQHSPIIHNPSYSATAHLSPLSQPTFEGSYSVNAIQTPRDIRRVGSDQKGGRSVSTS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
68	N-linked_Glycosylation	QYLNELQNFTLFAPI HHHHHCCCEEEEEEC	44.49	-
112	N-linked_Glycosylation	LQVRDLENGTYLEKR EEEEECCCCCCHHHH	56.24	-
152	N-linked_Glycosylation	DLLPSFQNASLQGIN HCCHHHHCHHCCCHH	29.50	-
200	N-linked_Glycosylation	SNYNAYTNSSTVLVP CCCCCCCCCCEEEEE	22.68	-
291	N-linked_Glycosylation	EGTSVSVNNSDYSPI CCCEEEECCCCCCCC	34.48	-
333	N-linked_Glycosylation	EKYLHGLNCSEFVKE HHHHCCCCHHHHHHH	31.68	-
348	Acetylation	LYFRDLEKFIQNGRK HHHHCHHHHHHCCCE	55.88	24489116
450	N-linked_Glycosylation	TKPYEIGNTSIYSID CCCEEECCEEEEECC	35.99	-
521	N-linked_Glycosylation	TIDYLRSNKTALNLL CHHHHHCCHHHHHHH	38.98	-
542	N-linked_Glycosylation	EDLIYSNNYSISTTV HHHHHCCCCCEEEEE	26.45	-
569	N-linked_Glycosylation	QKIVGSQNLTKISVS EEECCCCCCEEEEHH	51.91	-
663	N-linked_Glycosylation	PLSGITANSTNLRKF CCCCCCCCCCCHHHH	40.49	-
679	N-linked_Glycosylation	ELHLIPANVTQNLLD HCCEEECCCCCHHHC	31.82	-
688	N-linked_Glycosylation	TQNLLDCNGSISTKL CCHHHCCCCCCHHHC	47.08	-
809	Phosphorylation	TTPLIQHSPIIHNPS CCCEEECCCCCCCCC	11.04	21440633
830	Phosphorylation	LSPLSQPTFEGSYSV ECCCCCCCCCCEEEE	27.04	19779198

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YL001_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YL001_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YL001_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SLX5_YEAST	SLX5	genetic	20093466
SAC7_YEAST	SAC7	genetic	20093466
YOR1_YEAST	YOR1	genetic	20093466
ROY1_YEAST	ROY1	genetic	20093466
RS10A_YEAST	RPS10A	genetic	20093466
SSB1_YEAST	SSB1	physical	22940862
HSP72_YEAST	SSA2	physical	22940862

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.