| UniProt ID | ESL2_YEAST | |
|---|---|---|
| UniProt AC | P36168 | |
| Protein Name | EST/SMG-like protein 2 {ECO:0000303|PubMed:23893744} | |
| Gene Name | ESL2 {ECO:0000303|PubMed:23893744} | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 1195 | |
| Subcellular Localization | Cytoplasm . Nucleus . Peroxisome . A fraction of the protein co-localizes with peroxisomes. | |
| Protein Description | May be involved in the regulation of gene expression responses of environment-sensing pathways.. | |
| Protein Sequence | MPETSVQNPLRLSENENTRSMFLSASQQQRPSATPSFPRLVRNTTANLSLSDFQVLNPSSKRQNSNSVYDDINSSKRRISRPRFSDIEGKNNDHTYPERTTVKESEKNPSPRYVSSSKRALKRENSVGITQSSALISKSFSENGGSIAHEKWSPENMIKPLNVSQNSLAFVDAGSDEQSKSEIVGGFQRKSNNSQEINDKDNSARDQDFNNSGNNNNNNNHSSNNNDNNNNNNDDNNNNNNSNSRDNNNNSDDSNEREENDSCKPASNKRSGIALIQKLQELYKVIVKQEIELQERCSQLTNSQTTELKSLWTIYKINTDLVNNYVTFITTALLPSQPPHDLVIGQEIVEIYRIERRLWVYGTITFLDVLKNFSNFMDPEVCCQFITHVFVSLSTMISDIPSKYSITWLQRLGDLSRMAIALYPSSFIDWKLSAEHWYTEAMKYIYNHGKLYYHMSTVQQNTLEAFVNLGKSVFCQETFTPSPQYMQLVIDNIYQRAFVERNNGNLRNSLLIEYLKHSEAMLLPSFLESPDLQNVVLSYFIEKFGIDANGCNIFNAEDMFVQNPDFFKYFFRHGPSFAQSHILQIVGFGEPKNPFAILFELPKYLKERKDKKERKKSSNNDSSVTESSTGNSRNDNEDDDEIMSSTTSISDHDLLAEFFNDIDTLRRPILPSMLTNEAWLETLKFLNMTSLKCGIIVLRKFLHGPLGIALPHILPWIYFIISICLKSSQLSDPVSKEFWMIIVKRAFPWDTMVTFMNVLIVYLLDNQTSNSIIGDLCDDYDKLSLSELLELFNEGEELPEILGCWGTLWFDTICEKNTHSISSEDNFQEIGIKDYMALDSPTDGIIFDEKDENGEKFWKRACRTIFLFRELSRSFPIGVIIRNDPLIYRSSFQNTNILGSLVFKLEPLCNIHNNIPVLGALESIIDISEARSENNTDLHAVPELSVNEGDNIFHYVGYKKLRADYTCFDKNGEFLSASLYTTWYVPNSNNTNIEDNINYNSEKENEGLFLECIKSDYPEIDFKTTYFVFDATSWLRHSARIFKLAQNRLLRFAICLTTFQELRFLRKSKDENVMEAATRGIITIRQLYYENKVLPLRFTGNVATHIEENLEFEEQITWRTHVDEFVIESVMKAQEKLESASEPRLSPRRFNYVVLISDDDAMKKKAEEKEIKTLSTRFVFSLCTKLGEQRHLCTD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 65 | Phosphorylation | PSSKRQNSNSVYDDI CCCCCCCCCCHHHCC | 19823750 | ||
| 67 | Phosphorylation | SKRQNSNSVYDDINS CCCCCCCCHHHCCHH | 21551504 | ||
| 69 | Phosphorylation | RQNSNSVYDDINSSK CCCCCCHHHCCHHHC | 21551504 | ||
| 74 | Phosphorylation | SVYDDINSSKRRISR CHHHCCHHHCCCCCC | 19823750 | ||
| 75 | Phosphorylation | VYDDINSSKRRISRP HHHCCHHHCCCCCCC | 19823750 | ||
| 126 | Phosphorylation | RALKRENSVGITQSS HHHHHHCCCCCCHHH | 20377248 | ||
| 137 | Phosphorylation | TQSSALISKSFSENG CHHHHHHHHHHHCCC | 30377154 | ||
| 141 | Phosphorylation | ALISKSFSENGGSIA HHHHHHHHCCCCCCC | 21440633 | ||
| 146 | Phosphorylation | SFSENGGSIAHEKWS HHHCCCCCCCCCCCC | 21551504 | ||
| 164 | Phosphorylation | MIKPLNVSQNSLAFV CCCCCCCCCCCEEEE | 28889911 | ||
| 175 | Phosphorylation | LAFVDAGSDEQSKSE EEEEECCCCHHCHHH | 28889911 | ||
| 191 | Phosphorylation | VGGFQRKSNNSQEIN HCCEECCCCCCCCCC | 30377154 | ||
| 194 | Phosphorylation | FQRKSNNSQEINDKD EECCCCCCCCCCCCC | 17563356 | ||
| 251 | Phosphorylation | SRDNNNNSDDSNERE CCCCCCCCCCCCHHH | 28889911 | ||
| 284 | Ubiquitination | QKLQELYKVIVKQEI HHHHHHHHHHHHHHH | 24961812 | ||
| 617 | Phosphorylation | DKKERKKSSNNDSSV CHHHHHHCCCCCCCC | 28889911 | ||
| 623 | Phosphorylation | KSSNNDSSVTESSTG HCCCCCCCCCCCCCC | 28889911 | ||
| 628 | Phosphorylation | DSSVTESSTGNSRND CCCCCCCCCCCCCCC | 28889911 | ||
| 645 | Phosphorylation | DDDEIMSSTTSISDH CCHHHHHCCCCCCCH | 19779198 | ||
| 648 | Phosphorylation | EIMSSTTSISDHDLL HHHHCCCCCCCHHHH | 19779198 | ||
| 818 | Phosphorylation | DTICEKNTHSISSED HHHHCCCCCCCCCCC | 22890988 | ||
| 820 | Phosphorylation | ICEKNTHSISSEDNF HHCCCCCCCCCCCCC | 22890988 | ||
| 822 | Phosphorylation | EKNTHSISSEDNFQE CCCCCCCCCCCCCHH | 22890988 | ||
| 823 | Phosphorylation | KNTHSISSEDNFQEI CCCCCCCCCCCCHHC | 22890988 | ||
| 890 | Phosphorylation | NDPLIYRSSFQNTNI CCCCEECCCCCCCCC | 30377154 | ||
| 895 | Phosphorylation | YRSSFQNTNILGSLV ECCCCCCCCCCHHHE | 30377154 | ||
| 1141 | Phosphorylation | QEKLESASEPRLSPR HHHHHHCCCCCCCCC | 27017623 | ||
| 1146 | Phosphorylation | SASEPRLSPRRFNYV HCCCCCCCCCCCCEE | 27017623 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ESL2_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ESL2_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ESL2_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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