UniProt ID | H1_YEAST | |
---|---|---|
UniProt AC | P53551 | |
Protein Name | Histone H1 | |
Gene Name | HHO1 | |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
Sequence Length | 258 | |
Subcellular Localization | Nucleus . Chromosome . | |
Protein Description | Could act as an H1-type linker histone. Has been shown to bind DNA.. | |
Protein Sequence | MAPKKSTTKTTSKGKKPATSKGKEKSTSKAAIKKTTAKKEEASSKSYRELIIEGLTALKERKGSSRPALKKFIKENYPIVGSASNFDLYFNNAIKKGVEAGDFEQPKGPAGAVKLAKKKSPEVKKEKEVSPKPKQAATSVSATASKAKAASTKLAPKKVVKKKSPTVTAKKASSPSSLTYKEMILKSMPQLNDGKGSSRIVLKKYVKDTFSSKLKTSSNFDYLFNSAIKKCVENGELVQPKGPSGIIKLNKKKVKLST | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
26 | Phosphorylation | TSKGKEKSTSKAAIK CCCCCCCCCCHHHHH | 38.72 | 21440633 | |
27 | Phosphorylation | SKGKEKSTSKAAIKK CCCCCCCCCHHHHHH | 45.36 | 21440633 | |
28 | Phosphorylation | KGKEKSTSKAAIKKT CCCCCCCCHHHHHHH | 27.64 | 21440633 | |
47 | Phosphorylation | EEASSKSYRELIIEG HHHCCHHHHHHHHHH | 16.31 | 21440633 | |
64 | Phosphorylation | ALKERKGSSRPALKK HHHHCCCCCCHHHHH | 26.64 | 19823750 | |
65 | Phosphorylation | LKERKGSSRPALKKF HHHCCCCCCHHHHHH | 51.45 | 21551504 | |
82 | Phosphorylation | ENYPIVGSASNFDLY HCCCCCCCCCCCHHH | 20.03 | 30377154 | |
96 | Acetylation | YFNNAIKKGVEAGDF HHCHHHHCCCCCCCC | 63.17 | 24489116 | |
127 | Acetylation | SPEVKKEKEVSPKPK CHHHHCCCCCCCCCC | 72.75 | 25381059 | |
130 | Phosphorylation | VKKEKEVSPKPKQAA HHCCCCCCCCCCHHH | 28.44 | 19823750 | |
138 | Phosphorylation | PKPKQAATSVSATAS CCCCHHHHHHHHHHH | 32.45 | 30377154 | |
141 | Phosphorylation | KQAATSVSATASKAK CHHHHHHHHHHHHHH | 21.48 | 23749301 | |
143 | Phosphorylation | AATSVSATASKAKAA HHHHHHHHHHHHHHH | 24.77 | 30377154 | |
145 | Phosphorylation | TSVSATASKAKAAST HHHHHHHHHHHHHHC | 28.88 | 30377154 | |
164 | Phosphorylation | KKVVKKKSPTVTAKK HHHCCCCCCCCEECC | 34.38 | 28889911 | |
166 | Phosphorylation | VVKKKSPTVTAKKAS HCCCCCCCCEECCCC | 37.26 | 27717283 | |
168 | Phosphorylation | KKKSPTVTAKKASSP CCCCCCCEECCCCCC | 34.93 | 27717283 | |
173 | Phosphorylation | TVTAKKASSPSSLTY CCEECCCCCCCCCCH | 52.22 | 22369663 | |
174 | Phosphorylation | VTAKKASSPSSLTYK CEECCCCCCCCCCHH | 33.39 | 22369663 | |
176 | Phosphorylation | AKKASSPSSLTYKEM ECCCCCCCCCCHHHH | 39.67 | 22890988 | |
177 | Phosphorylation | KKASSPSSLTYKEMI CCCCCCCCCCHHHHH | 28.28 | 22890988 | |
179 | Phosphorylation | ASSPSSLTYKEMILK CCCCCCCCHHHHHHH | 34.20 | 22890988 | |
180 | Phosphorylation | SSPSSLTYKEMILKS CCCCCCCHHHHHHHH | 15.39 | 28132839 | |
186 | Acetylation | TYKEMILKSMPQLND CHHHHHHHHCCCCCC | 33.51 | 24489116 | |
207 | Acetylation | IVLKKYVKDTFSSKL EEEEHHHHHHHHHHC | 48.22 | 22865919 | |
213 | Acetylation | VKDTFSSKLKTSSNF HHHHHHHHCCCCCCH | 53.45 | 22865919 | |
216 | Phosphorylation | TFSSKLKTSSNFDYL HHHHHCCCCCCHHHH | 48.07 | 30377154 | |
217 | Phosphorylation | FSSKLKTSSNFDYLF HHHHCCCCCCHHHHH | 23.00 | 30377154 | |
218 | Phosphorylation | SSKLKTSSNFDYLFN HHHCCCCCCHHHHHH | 46.91 | 30377154 | |
222 | Phosphorylation | KTSSNFDYLFNSAIK CCCCCHHHHHHHHHH | 14.73 | 30377154 | |
226 | Phosphorylation | NFDYLFNSAIKKCVE CHHHHHHHHHHHHHH | 24.84 | 30377154 | |
229 | Acetylation | YLFNSAIKKCVENGE HHHHHHHHHHHHCCC | 39.58 | 24489116 | |
248 | Acetylation | KGPSGIIKLNKKKVK CCCCCEEEECCCCCC | 44.05 | 25381059 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of H1_YEAST !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of H1_YEAST !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of H1_YEAST !! |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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Phosphorylation | |
Reference | PubMed |
"A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-174, AND MASSSPECTROMETRY. | |
"Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-174, AND MASSSPECTROMETRY. | |
"Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae."; Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.; J. Proteome Res. 6:1190-1197(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-174, AND MASSSPECTROMETRY. |