dbPTM

PHO89_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PHO89_YEAST
UniProt AC	P38361
Protein Name	Phosphate permease PHO89
Gene Name	PHO89
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	574
Subcellular Localization	Membrane Multi-pass membrane protein.
Protein Description	Sodium-phosphate symporter. Active in early growth phase..
Protein Sequence	MALHQFDYIFAIAMLFAFLDAFNIGANDVANSFASSISSRSLKYWQAMVLAGLCEFLGAVLAGARVSGTIKNNIIDSSIFTNDPAVLMLTMTSALIGSSCWLTFATAIGMPVSTTHSIVGGTIGAGIAAGGANGVVWGWSGVSQIIASWFIAPILAGAIAAIVFSISRFSVLEVKSLERSIKNALLLVGVLVFATFSILTMLIVWKGSPNLHLDDLSETETAVSIVLTGAIASIVYFIFFYPFYRRKVLDQDWTLKLIDIFRGPSFYFKSTDDIPPMPEGHQLTIDYYEGRRNLGTTVSVEDEENKAASNSNDSVKNKEDIQEVDLVRTETEPETKLSTKQYWWSLLKQGPKKWPLLFWLVISHGWTQDVIHAQVNDRDMLSGDLKGMYERSKFYDNRVEYIYSVLQAITAATMSFAHGANDVANATGPLSAVYVIWKTNTIGAKSEVPVWVLAYGGVALVIGCWTYGYNIIKNLGNKMILQSPSRGFSIELAVAITTVMATQLGIPTSTTQIAVGGIVAVGLCNKDLKSVNWRMVAWCYSGWFLTLPIAGLIAGIINGIILNAPRFGVEYQMT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
299	Phosphorylation	RNLGTTVSVEDEENK CCCCCEEEECHHHCH	20.07	29650682
309	Phosphorylation	DEENKAASNSNDSVK HHHCHHHCCCCCHHC	45.72	27214570
314	Phosphorylation	AASNSNDSVKNKEDI HHCCCCCHHCCHHHH	38.96	27214570
329	Phosphorylation	QEVDLVRTETEPETK HHHCCEEECCCCCCC	39.52	27017623
331	Phosphorylation	VDLVRTETEPETKLS HCCEEECCCCCCCCC	57.11	17330950
338	Phosphorylation	TEPETKLSTKQYWWS CCCCCCCCHHHHHHH	34.80	27017623
339	Phosphorylation	EPETKLSTKQYWWSL CCCCCCCHHHHHHHH	32.38	27017623

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PHO89_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PHO89_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PHO89_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PHO90_YEAST	PHO90	genetic	11779791
PHO91_YEAST	PHO91	genetic	11779791
SKI7_YEAST	SKI7	genetic	20835226
RL3_YEAST	RPL3	physical	20835226
ERF3_YEAST	SUP35	genetic	20835226
YPT53_YEAST	YPT53	genetic	20526336
AMPD_YEAST	AMD1	genetic	21623372
ATP5E_YEAST	ATP15	genetic	21623372
METC_YEAST	IRC7	genetic	21623372
ALLC_YEAST	DAL2	genetic	21623372
PHO89_YEAST	PHO89	physical	23216645
PHO84_YEAST	PHO84	genetic	25266663
APC11_YEAST	APC11	genetic	27708008
KIN28_YEAST	KIN28	genetic	27708008
CDC53_YEAST	CDC53	genetic	27708008
RPB1_YEAST	RPO21	genetic	27708008
NSE3_YEAST	NSE3	genetic	27708008
SYF1_YEAST	SYF1	genetic	27708008
RSP5_YEAST	RSP5	genetic	27708008
PRP18_YEAST	PRP18	genetic	27708008
SMD1_YEAST	SMD1	genetic	27708008
CDC12_YEAST	CDC12	genetic	27708008
MET30_YEAST	MET30	genetic	27708008
MCM10_YEAST	MCM10	genetic	27708008
ARP4_YEAST	ARP4	genetic	27708008
EXO70_YEAST	EXO70	genetic	27708008
KTHY_YEAST	CDC8	genetic	27708008
PRS7_YEAST	RPT1	genetic	27708008
CDC25_YEAST	CDC25	genetic	27708008
TAD3_YEAST	TAD3	genetic	27708008
DCP2_YEAST	DCP2	genetic	27708008
TYSY_YEAST	CDC21	genetic	27708008
NAB3_YEAST	NAB3	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PHO89_YEAST

Related Literatures of Post-Translational Modification