SYFM_YEAST - dbPTM
SYFM_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SYFM_YEAST
UniProt AC P08425
Protein Name Phenylalanine--tRNA ligase, mitochondrial
Gene Name MSF1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 469
Subcellular Localization Mitochondrion matrix .
Protein Description Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation..
Protein Sequence MFLNRMMKTRTGLYRLYSTLKVPHVEINGIKYKTDPQTTNVTDSIIKLTDRSLHLKESHPVGILRDLIEKKLNSVDNTFKIFNNFKPVVTTMENFDSLGFPKDHPGRSKSDTYYINETHLLRTHTSAHELECFQKIRNDSDNIKSGFLISADVYRRDEIDKTHYPVFHQMEGATIWKRTKADVGVKEPMYIEKIREDIRQVENLLNKENVKITVDDDTIPLKENNPKQEYMSDLEVDLCSQHLKRSIELIVSEVFNKKISSMIKNKANNTPKELKVRWINAYFPWTAPSWEIEVWWQGEWLELCGCGLIRQDVLLRAGYKPSETIGWAFGLGLDRIAMLLFEIPDIRLLWSRDERFSRQFSKGLITSFKPYSKHPGSFRDVAFWLPEDKPDIHQVHENDLMEIIRNIAGDLVESVKLVDSFTHPKTGRKSMCYRINYQSMDRNLTNAEVNTLQDMVCSKLVKEYSVELR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
260PhosphorylationEVFNKKISSMIKNKA
HHHHHHHHHHHHHCC		23.8028889911
261PhosphorylationVFNKKISSMIKNKAN
HHHHHHHHHHHHCCC		28.1828889911
270PhosphorylationIKNKANNTPKELKVR
HHHCCCCCCHHHEEE		35.2328889911
369AcetylationKGLITSFKPYSKHPG
CCCHHCCCCCCCCCC		42.7024489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SYFM_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SYFM_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SYFM_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
IF2A_YEASTSUI2genetic
19061648
RU1C_YEASTYHC1genetic
19061648
RRP41_YEASTSKI6genetic
19061648
IF2M_YEASTIFM1genetic
19061648
AEP3_YEASTAEP3genetic
19061648
RFC5_YEASTRFC5genetic
27708008
ACT_YEASTACT1genetic
27708008
CDC14_YEASTCDC14genetic
27708008
PRS8_YEASTRPT6genetic
27708008
NUP57_YEASTNUP57genetic
27708008
TIM44_YEASTTIM44genetic
27708008
SWD2_YEASTSWD2genetic
27708008
HYM1_YEASTHYM1genetic
27708008
CD123_YEASTCDC123genetic
27708008
GEM1_YEASTGEM1genetic
27708008
QRI7_YEASTQRI7genetic
27708008
AVL9_YEASTAVL9genetic
27708008
AEP2_YEASTAEP2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SYFM_YEAST

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Related Literatures of Post-Translational Modification

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