TDA2_YEAST - dbPTM
TDA2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TDA2_YEAST
UniProt AC P40045
Protein Name Topoisomerase I damage affected protein 2
Gene Name TDA2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 126
Subcellular Localization Cytoplasm . Cell projection . Concentrates at cytoplasmic punctate structures and localizes at the mating projection tip.
Protein Description
Protein Sequence MSMQIEIKDGRSDNSPLPERKLVTLIQESYDSLKDDNEINLSTESTSNLLIKLVLEKLEKHSSLYKYIASVTTLNIEGLNEENANFSLKNDIGASWESKKDGIFNYKLEDKNNNECYLITILWLHK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MSMQIEIKD
------CCCEEEEEC
21.2822814378
57AcetylationLIKLVLEKLEKHSSL
HHHHHHHHHHHCCHH
58.7624489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TDA2_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TDA2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TDA2_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
EIF3G_YEASTTIF35physical
16554755
YIP2_YEASTYIL152Wphysical
16554755
AIM21_YEASTAIM21physical
16554755
SSB2_YEASTSSB2physical
16554755
YD366_YEASTYDR366Cphysical
11283351
PFD6_YEASTYKE2physical
11283351
SRS2_YEASTSRS2genetic
21459050
DPM1_YEASTDPM1genetic
23891562
SLX5_YEASTSLX5genetic
27708008
TBP7_YEASTYTA7genetic
27708008
RL37A_YEASTRPL37Agenetic
27708008
LIPB_YEASTLIP2genetic
27708008
RL6B_YEASTRPL6Bgenetic
27708008
SWD1_YEASTSWD1genetic
27708008
YAJ9_YEASTYAR029Wgenetic
27708008
RL23A_YEASTRPL23Agenetic
27708008
RL23B_YEASTRPL23Agenetic
27708008
FAT1_YEASTFAT1genetic
27708008
HPC2_YEASTHPC2genetic
27708008
RV161_YEASTRVS161genetic
27708008
YCY0_YEASTYCR090Cgenetic
27708008
NHP10_YEASTNHP10genetic
27708008
GPR1_YEASTGPR1genetic
27708008
TPS2_YEASTTPS2genetic
27708008
VPS41_YEASTVPS41genetic
27708008
TRM1_YEASTTRM1genetic
27708008
RPA14_YEASTRPA14genetic
27708008
RV167_YEASTRVS167genetic
27708008
UBP6_YEASTUBP6genetic
27708008
MRM2_YEASTMRM2genetic
27708008
RTF1_YEASTRTF1genetic
27708008
OCA5_YEASTOCA5genetic
27708008
CBF1_YEASTCBF1genetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
DHOM_YEASTHOM6genetic
27708008
CANB_YEASTCNB1genetic
27708008
PER33_YEASTPER33genetic
27708008
ARP6_YEASTARP6genetic
27708008
COQ11_YEASTYLR290Cgenetic
27708008
VRP1_YEASTVRP1genetic
27708008
GTR1_YEASTGTR1genetic
27708008
RIM13_YEASTRIM13genetic
27708008
RAD14_YEASTRAD14genetic
27708008
COQ2_YEASTCOQ2genetic
27708008
MSO1_YEASTMSO1genetic
27708008
YOL19_YEASTYOL019Wgenetic
27708008
2A5D_YEASTRTS1genetic
27708008
PT127_YEASTPET127genetic
27708008
BUB3_YEASTBUB3genetic
27708008
IRC23_YEASTIRC23genetic
27708008
ALG8_YEASTALG8genetic
27708008
SFL1_YEASTSFL1genetic
27708008
PMA2_YEASTPMA2genetic
27708008
YP039_YEASTYPL039Wgenetic
27708008
UBP16_YEASTUBP16genetic
27708008
ELP4_YEASTELP4genetic
27708008
BEM4_YEASTBEM4genetic
27708008
FLC1_YEASTFLC1genetic
27708008
TDA2_YEASTTDA2physical
28706108
AIM21_YEASTAIM21physical
28706108
RGS20_HUMANRGS20physical
27107014
K1C15_HUMANKRT15physical
27107014

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TDA2_YEAST

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Related Literatures of Post-Translational Modification

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