IRC23_YEAST - dbPTM
IRC23_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID IRC23_YEAST
UniProt AC Q08416
Protein Name Increased recombination centers protein 23
Gene Name IRC23
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 157
Subcellular Localization Endoplasmic reticulum membrane
Multi-pass membrane protein .
Protein Description Is probably involved in a pathway contributing to genomic integrity..
Protein Sequence MIEALEIVLLLVIQSLQYICRTCIAFLLIPFLGLYAFDLFLYVYRMILYLSQMFNYKRKLGRSKTNNRPHSPRLHKIYSSGDCMDTLIGQVRDLRVFLLSTIHSHSKRFFSTRFQTKSGINSAIDANDVETTSDVSSFTNLHLTRSSEEGYYIAGSI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
132PhosphorylationDANDVETTSDVSSFT
CCCCCCCCCCCHHHC		14.9319779198
133PhosphorylationANDVETTSDVSSFTN
CCCCCCCCCCHHHCC		43.3519779198
137PhosphorylationETTSDVSSFTNLHLT
CCCCCCHHHCCEEEE		35.6219779198
147PhosphorylationNLHLTRSSEEGYYIA
CEEEECCCCCCEEEE		36.0519779198
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of IRC23_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of IRC23_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of IRC23_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ERP4_YEASTERP4genetic
16269340
ALG6_YEASTALG6genetic
16269340
HRD1_YEASTHRD1genetic
16269340
TSC3_YEASTTSC3genetic
16269340
PMA1_YEASTPMA1genetic
16269340
TRM1_YEASTTRM1genetic
20093466
UME6_YEASTUME6genetic
20093466
SGPL_YEASTDPL1genetic
20093466
BL1S4_YEASTCNL1genetic
20093466
YIP4_YEASTYIP4genetic
20093466
MED5_YEASTNUT1genetic
20093466
YG34_YEASTYGR122Wgenetic
20093466
PACC_YEASTRIM101genetic
20093466
RIM13_YEASTRIM13genetic
20093466
ERG2_YEASTERG2genetic
20093466
NST1_YEASTNST1genetic
20093466
EOS1_YEASTEOS1genetic
20093466
GRE2_YEASTGRE2genetic
20093466
RL7B_YEASTRPL7Bgenetic
20093466
YP091_YEASTNVJ2genetic
20093466
GPR1_YEASTGPR1genetic
27708008
RLA1_YEASTRPP1Agenetic
27708008
UME6_YEASTUME6genetic
27708008
SGPL_YEASTDPL1genetic
27708008
MRM2_YEASTMRM2genetic
27708008
MED5_YEASTNUT1genetic
27708008
YIP4_YEASTYIP4genetic
27708008
DAL81_YEASTDAL81genetic
27708008
IME2_YEASTIME2genetic
27708008
ENG2_YEASTACF2genetic
27708008
RIM13_YEASTRIM13genetic
27708008
ERG2_YEASTERG2genetic
27708008
NST1_YEASTNST1genetic
27708008
CPT1_YEASTCPT1genetic
27708008
PALA_YEASTRIM20genetic
27708008
MED1_YEASTMED1genetic
27708008
MDM36_YEASTMDM36genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of IRC23_YEAST

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Related Literatures of Post-Translational Modification

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