ARI1_YEAST - dbPTM
ARI1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ARI1_YEAST
UniProt AC P53111
Protein Name NADPH-dependent aldehyde reductase ARI1
Gene Name ARI1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 347
Subcellular Localization Cytoplasm . Nucleus .
Protein Description NADPH-dependent aldehyde reductase involved in the detoxification of aldehyde inhibitors derived from lignocellulosic biomass conversion. Reduces commonly detected inhibitors in biomass conversion hydrolysates such as furfural, 5-hydroxymethylfurfural (HMF), cinnamic aldehyde, benzaldehyde, phenylacetaldehyde, and anisaldehyde..
Protein Sequence MTTDTTVFVSGATGFIALHIMNDLLKAGYTVIGSGRSQEKNDGLLKKFNNNPKLSMEIVEDIAAPNAFDEVFKKHGKEIKIVLHTASPFHFETTNFEKDLLTPAVNGTKSILEAIKKYAADTVEKVIVTSSTAALVTPTDMNKGDLVITEESWNKDTWDSCQANAVAAYCGSKKFAEKTAWEFLKENKSSVKFTLSTINPGFVFGPQMFADSLKHGINTSSGIVSELIHSKVGGEFYNYCGPFIDVRDVSKAHLVAIEKPECTGQRLVLSEGLFCCQEIVDILNEEFPQLKGKIATGEPATGPSFLEKNSCKFDNSKTKKLLGFQFYNLKDCIVDTAAQMLEVQNEA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
40AcetylationGSGRSQEKNDGLLKK
CCCCCCCCCCCHHHH		53.3424489116
98AcetylationFETTNFEKDLLTPAV
EECCCCCHHCCCHHH		49.9224489116
178AcetylationGSKKFAEKTAWEFLK
CCHHHHHHHHHHHHH		39.8624489116
185AcetylationKTAWEFLKENKSSVK
HHHHHHHHHCCCCCE		65.6424489116
259AcetylationAHLVAIEKPECTGQR
EEEEEEECCCCCCCE		39.7524489116
308UbiquitinationTGPSFLEKNSCKFDN
CCCCHHHCCCCCCCC		57.2023749301
308AcetylationTGPSFLEKNSCKFDN
CCCCHHHCCCCCCCC		57.2024489116
317UbiquitinationSCKFDNSKTKKLLGF
CCCCCCHHHHHCCCC		71.2922817900
319UbiquitinationKFDNSKTKKLLGFQF
CCCCHHHHHCCCCEE		45.2022817900
320UbiquitinationFDNSKTKKLLGFQFY
CCCHHHHHCCCCEEE		54.9323749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ARI1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ARI1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ARI1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
DPO4_YEASTPOL4physical
16554755
ROK1_YEASTROK1physical
16554755
YMS4_YEASTYMR034Cphysical
16554755
CMR1_YEASTCMR1genetic
22842922
PFKA2_YEASTPFK2genetic
27708008
LDB17_YEASTLDB17genetic
27708008
RLA4_YEASTRPP2Bgenetic
27708008
STB5_YEASTSTB5genetic
27708008
VPS53_YEASTVPS53genetic
27708008
PIR5_YEASTYJL160Cgenetic
27708008
YJ24_YEASTKCH1genetic
27708008
YPT7_YEASTYPT7genetic
27708008
PLB2_YEASTPLB2genetic
27708008
GBLP_YEASTASC1genetic
27708008
RM44_YEASTMRPL44genetic
27708008
MKS1_YEASTMKS1genetic
27708008
BRE5_YEASTBRE5genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ARI1_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory