| UniProt ID | CMR1_YEAST | |
|---|---|---|
| UniProt AC | Q12510 | |
| Protein Name | DNA damage-binding protein CMR1 {ECO:0000305|PubMed:22367945} | |
| Gene Name | CMR1 {ECO:0000303|PubMed:22367945} | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 522 | |
| Subcellular Localization | Cytoplasm . Nucleus . | |
| Protein Description | DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA in vitro. [PubMed: 22367945 May be involved in DNA-metabolic processes] | |
| Protein Sequence | MPELTEFQKKRLENIKRNNDLLKKLHLSGVASQIKHEAGVLEKSRAPAKKKQKTTNTRATKSASPTLPTRRSRRLRGESADDVKGIPNVNDNQLLKMGSPDGQDKNFIDAIKEKPVIGDVKLSDLIKDEDESALLEKFKRFNNGNFSSGDFFEEIKKRQGDVTGMDEFDLDLYDVFQPNEIKITYERISATYFHPAMEKKLIIAGDTSGTVGFWNVRDEPLADSEEDRMEEPDITRVKLFTKNVGRIDCFPADTSKILLTSYDGSIRSVHLNNLQSEEVLTLKNEYDDSLGISDCQFSYENPNVLFLTTLGGEFTTFDTRVKKSEYNLRRLADKKIGSMAINPMRPYEIATGSLDRTLKIWDTRNLVKKPEWSQYEDYPSHEIVSTYDSRLSVSAVSYSPTDGTLVCNGYDDTIRLFDVKSRDHLSAKLEPKLTIQHNCQTGRWTSILKARFKPNKNVFAIANMKRAIDIYNSEGQQLAHLPTATVPAVISWHPLRNWIAGGNSSGKIFLFTDDSGTIKQEE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 5 | Phosphorylation | ---MPELTEFQKKRL ---CCCHHHHHHHHH | 29734811 | ||
| 62 | Phosphorylation | TNTRATKSASPTLPT CCCCCCCCCCCCCCC | 27214570 | ||
| 64 | Phosphorylation | TRATKSASPTLPTRR CCCCCCCCCCCCCHH | 24930733 | ||
| 66 | Phosphorylation | ATKSASPTLPTRRSR CCCCCCCCCCCHHHH | 29688323 | ||
| 69 | Phosphorylation | SASPTLPTRRSRRLR CCCCCCCCHHHHCCC | 17287358 | ||
| 79 | Phosphorylation | SRRLRGESADDVKGI HHCCCCCCHHHCCCC | 27214570 | ||
| 99 | Phosphorylation | NQLLKMGSPDGQDKN HHEEECCCCCCCCCC | 17287358 | ||
| 137 | Acetylation | DESALLEKFKRFNNG CHHHHHHHHHHHCCC | 24489116 | ||
| 147 | Phosphorylation | RFNNGNFSSGDFFEE HHCCCCCCCHHHHHH | 19779198 | ||
| 148 | Phosphorylation | FNNGNFSSGDFFEEI HCCCCCCCHHHHHHH | 19779198 | ||
| 224 | Phosphorylation | RDEPLADSEEDRMEE CCCCCCCCHHHHCCC | 27214570 | ||
| 426 | Phosphorylation | VKSRDHLSAKLEPKL CCCCCCCCCCCCCCE | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CMR1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CMR1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CMR1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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